目的:探讨尾加压素Ⅱ受体拮抗剂Urantide对动脉粥样硬化(atherosclerosis,AS)大鼠脂肪肝组织中信号转导与转录激活因子3(signal transducer and activator of transcription 3,STAT3)表达的影响。方法:30只雄性Wistar大鼠随机分为正常组...
supported by grants from the National Natural Science Foundation of China(81370379 and 30900526 to SHZ);the Natural Science Foundation of Shaanxi Province(2017BSHQYXMZZ18 to YFL,2012KJXX-07,2014JQ4137 to SHZ and 2014FWPT07 to EQL);the Fundamental Research Fund for the Central Universities(SHZ).
Increasing levels of plasma urotensin II(UII)are positively associated with atherosclerosis.In this study we investigated the role of macrophage-secreted UII in atherosclerosis progression,and evaluated the therapeuti...