目的探讨三阴型乳腺癌(triple-negative breast cancer,TNBC)中VISTA及Foxp3表达的临床病理意义。方法应用GEPIA2基于生物信息数据库TCGA分析VISTA mRNA、Foxp3 mRNA在TNBC中的表达量及与患者预后的关系。收集160例TNBC及160例正常乳腺...
supported by grants from the National Natural Science Foundation of China (U1904147,U20A20369);Shenzhen Science and Technology Program (KQTD20190929173853397,China);“Pearl River Talent Plan”Innovation and Entrepreneurship Team Project of Guangdong Province (2019ZT08Y464,China)。
Developing new therapeutic agents for cancer immunotherapy is highly demanding due to the low response ratio of PD-1/PD-L1 blockade in cancer patients.Here,we discovered that the novel immune checkpoint VISTA is highl...