supported by the National Natural Science Foundation of China(21871090,21725203);the National Key Research and Development Program of China(2020YFA0710200);the Shanghai Science and Technology Innovation Action Plan(20JC1416900);the Innovation Program of Shanghai Municipal Education Commission(2023ZKZD37);the Fundamental Research Funds for the Central Universities.
We report a tandem asymmetric Cu-catalyzed propargylic amination(ACPA)/Ag-catalyzed carboxylative cyclization(SCC)with CO_(2) to 5-methylidene-2-oxazolidinones;even with tetrasubstituted stereocenters.By varying pyrid...
supported by the National Natural Science Foundation of China(22172048,22072042).
Upcycling of plastic waste into N-containing compound is a novel and attractive strategy for its disposal and will opens up a promising direction for the production of value-added amines.Herein,an efficient strategy f...
supported by the National Natural Science Foundation of China(22188101);Sichuan Science and Technology Program(2021YJ0561)。
An efficient catalytic asymmetric dearomatizing amination of 2-naphthols and phenols catalyzed by N,N′-dioxide-copper(I)complex as a chiral catalyst was presented.A variety of optically activeβ-naphthalenone compoun...
supported by the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (18KJA350001);the Priority Academic Program Development of the Jiangsu Higher Education Institutes (PAPD)。
Catalytic amination of alkenes is one of the most attractive reactions for the construction of complex heterocycles with nitrogen centers. Herein, we present that synergistic photoredox and cobaloxime catalysis allows...
supported by the National Natural Science Foundation of China(21772085,21971107,2201101);China Postdoctoral Science Foundation(2021T140309,2021M691511)。
Alkylamines are important motifs in pharmaceutical and material sciences.The existing reports of C-H amination are limited to ammonia,diazo and azide nitrogen sources.This work describes a rapid construction of C-N bo...
the National Natural Science Foundation of China(21602028);Beijing National Laboratory for Molecular Sciences(BNLMS201913);the Recruitment Program of Global Experts;Fuzhou University。
Nitrogen-containing motifs are widely present in natural products, bioactive molecules, and drugs. Accordingly, effective synthetic methods with high efficiency and diversity are highly desirable. Here, we present the...
supported by the Deutsche Forschungsgemeinschaft(ME 1805/15-1)。
Chiral β-amino alcohols are important building blocks for the synthesis of drugs, natural products, chiral auxiliaries, chiral ligands and chiral organocatalysts. The catalytic asymmetric β-amination of alcohols off...
supported by the National Natural Science Foundation of China (21535004, 91753111, 21605097, 21775092, 21390411);the Key Research and Development Program of Shandong Province (2018YFJH0502);the Natural Science Foundation of Shandong Province of China (ZR2016BQ01, ZR2018JL008);the China Postdoctoral Science Foundation (2017M610442)
A novel Ag(Ⅰ)-catalyzed benzylic amination reaction with in situ generation of NH-1,2,3-triazoles for N^2-substituted 1,2,3 triazole scaffolds is described. This protocol is achieved with easily accessible substrate,...
supported by the National Natural Science Foundation of China (21102005);Program for Innovative Research Team of Science and Technology in the University of Henan Province (18IRTSTHN004)
A method for Cu(Ⅱ)-catalyzed dehydrogenative amidation of azoarene using air as the terminal oxidant was developed. Various amides, such as arylamides, alkylamides, lactams, and imides, are all effective amidation re...
financially supported by the National Natural Science Foundation of China(21172033,21372041,21302017)
A novel copper-catalyzed direct C–N formation reaction of simple arenes with cheap and pharmacological saccharin derivatives under relatively mild conditions was developed with arenes as limiting reagents.This work p...