the National Natural Science Foundation of China(Nos.22307009,82374155,82073997,82104376);the Sichuan Science and Technology Program(Nos.2023NSFSC1108,2024NSFTD0023);the Postdoctoral Research Project of Sichuan Province;the Xinglin Scholar Research Promotion Project of Chengdu University of TCM.
Background:Triple-negative breast cancer(TNBC),characterized by its lack of traditional hormone receptors and HER2,presents a significant challenge in oncology due to its poor response to conventional therapies.Autoph...
Supported by the National Natural Science Foundation of China,No.82272996;the Science and Technology Program of Guangzhou,No.202206010081.
Colorectal cancer(CRC)ranks third in the number of cancers mainly because of the inability to diagnose it at an early stage.The pathogenesis of CRC is complicated,which is the result of the complex interaction of mult...
This work was supported by the National Natural Science Foundation of China(Nos.82022022,32371018 and 82071274);a Project Funded by Jiangsu Key Laboratory of Neuropsychiatric Diseases(BM2013003,China);a Key Project of Natural Science Foundation of Jiangsu Provincial Higher Education Institutions(23KJA310005,China);a Project Funded by the Interdisciplinary Basic Frontier Innovation Program of Suzhou Medical College of Soochow University(MP13202823,China);a Project Funded by the Suzhou International Joint Laboratory for Diagnosis and Treatment of Brain Diseases,and a Project Funded by the Priority Academic Program Development of the Jiangsu Higher Education Institutes(PAPD).J.H.M.P.was supported Science Foundation Ireland(17/COEN/3474,17/JPND/3455);Q.M.is a recipient of an RCSI International StAR Ph.D.scholarship.N.L.was supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province.K.Y.T.,was supported by the financial support from the Science and Technology Development Fund,Macao SAR(File no.0062/2021/A,China);University of Macao(File no.MYRG2022-00171-FHS,China).
Growing evidences indicate that dysfunction of autophagy contributes to the disease pathogenesis of amyotrophic lateral sclerosis(ALS)and frontotemporal dementia(FTD),two neurodegenerative disorders.The GGGGCC·GGCCCC...