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CD23 mediated the induction of pro-inflammatory cytokines Interleukin-1 beta and tumor necrosis factors-alpha in Aspergillus fumigatus keratitis被引量：2
《Chinese Medical Journal》2021年第8期1001-1003,共3页Hai-Jing Yan Nan Jiang Li-Ting Hu Qiang Xu Xu-Dong Peng Hua Yang Wen-Yi Zhao Le-Yu Lyu Li-Mei Wang Cheng-Ye Che 
To the Editor:Fungal keratitis is primarily caused by pathogenic fungi species,such as Fusarium solani and Aspergillus fumigatus.The incidence of A.fumigatus has been increased worldwide.[1]Although new therapies have...
关键词：DRUGS diagnosis CD23 
Lysosomal-associated protein transmembrane-4 beta: a novel potential biomarker for cancer therapy with multiple functions
《Chinese Medical Journal》2021年第1期38-40,共3页Xi-Chao Xu Jian-Guo Feng Li-Ling Tang 
supported by the grants from the Natural Science Foundation of China(No.31670952);the Fundamental Research Funds for the Central Universities(No.106112017CDJXSYY0001);Graduate Research and Innovation Foundation of Chongqing(No.CYB19043)。
LAPTM4B,which is a proto-oncogene,plays important roles in cancer progression,including clinical stages and pathologic grades.[1]The LAPTM4B gene encodes the lysosomal-associated protein transmembrane-4 beta(LAPTM4B)p...
关键词：cancer clinical CHEMOTHERAPY 
Effect of 15-Deoxy-A^12,14-prostaglandin J2 Nanocapsules on Inflammation and Bone Regeneration in a Rat Bone Defect Model被引量：3
《Chinese Medical Journal》2017年第3期347-356,共10页Qi Tang Li-Li Chen Fen Wei Wei-Lian Sun Li-Hong Lei Pei-Hui Ding Jing-Yi Tan Xiao-Tao Chen Yan-Min Wu 
Background： 15-Deoxy-^△^12、14-prostaglandin J2 （15d-PGJ2）, one of the major metabolites from prostaglandin D2 in arachidonic acid metabolic pathway, has potential anti-inflammatory properties. The objective of th...
关键词：15-Deoxy-Am4-prostaglandin J  lnterleukin-I Beta INTERLEUKIN-6 NANOCAPSULES OSTEOGENESIS 
A Novel Missense Mutation in the Spectrin Beta Nonerythrocytic 2 Gene Likely Associated with Spinocerebellar Ataxia Type 5
《Chinese Medical Journal》2016年第20期2516-2517,共2页Li-Zhi Liu Ming Ren Mao Li Yu-Ting Ren Bo Sun Xiao-Sun Sun Si-Yu Chen Si-Yuan Li Xu-Sheng Huang 
To the Editor：Spinocerebellar ataxia type 5 （SCA5） is a rare autosomal dominant spinocerebellar ataxia.Mutations in the spectrin beta nonerythrocytic 2 gene （SPTBN2） are known to cause SCA5,six of which have been...
Mutation Analysis of Gap Junction Protein Beta 1 and Genotype-Phenotype Correlation in X-linked Charcot-Marie- Tooth Disease in Chinese Patients被引量：7
《Chinese Medical Journal》2016年第9期1011-1016,共6页Bo Sun Zhao-HuiChen Li Ling Yi-Fan Li Li-Zhi Liu Fei Yang Xu-Sheng Huang 
Background： Among patients with Charcot-Marie-Tooth disease （CMT）, the X-linked variant （CMTX） caused by gap junction protein beta 1 （GJB1） gene mutation is the second most frequent type, accounting for approxi...
关键词：Connexin 32 ELECTROPHYSIOLOGY Gap Junction Protein Beta 1 Genetic Mutation X-linked Charcot-Marie-Tooth Disease 
Association Analysis of Proteasome Subunits and Transporter Associated with Antigen Processing on Chinese Patients with Parkinson＇s Disease被引量：3
《Chinese Medical Journal》2016年第9期1053-1058,共6页Ming-Shu Mo Wei Huang Cong-Cong Sun Li-Min Zhang Luan Cen You-Sheng Xiao Guo-Fei Li Xin-Ling Yang Shao-Gang Qu Ping-Yi Xu 
Supplementary information is linked to the online version of the paper on the Chinese Medical Journal website.This work was supported by research grants from the National High Technology Research and Development Program of China （grant No. 2007AA02Z460）, the State Key Development Program for Basic Research of China （grant No. 2011CB510000）, the National Natural Science Foundation of China （grant No. 81271428, 81471292, U1503222, and 81430021） and the key point Science Foundation of Guangdong of China （No. 2015A030311021）, a grant supported by technology project of Guangzhou （No. 20151260） and a grant supported by assisting research project of science and technology for Xinjiang （No. 201591160）.
Background： Proteasome subunits （PSMB） and transporter associated with antigen processing （TAP） loci are located in the human leukocyte antigen （HLA） Class I1 region play important roles in immune response and ...
关键词：Han Chinese Proteasome Subunit Beta Type Sporadic Parkinson＇s Disease TAP 
The Implication and Significance of Beta 2 Microglobulin： A Conservative Multifunctional Regulator被引量：16
《Chinese Medical Journal》2016年第4期448-455,共8页Ling Li Mei Dong Xiao-Guang Wang 
This study was funded by the grant from the National Nature Science Foundation of China
Objective： This review focuses on the current knowledge on the implication and significance of beta 2 microglobulin （β2M）, a conservative immune molecule in vertebrate.Data Sources： The data used in this review w...
关键词：Beta 2 Microglobulin Immune Dysregulation Major Histocompatibility Complex Class I or Like Molecules 
Cochlear implantation effect on deaf children with gap junction protein beta 2 gene mutation被引量：4
《Chinese Medical Journal》2013年第7期1298-1301,共4页KONG Ying LIU Sha WANG Su-ju Li Shu-jing LIANG Shuang 
This study was supported by grants from the National Natural Science Foundation of China （No. 81170916 and No. 30872859） and the Scientific Research Foundation for Capital Health Development （No. 2011-1017-05）.
Background The popularization and promotion of gene diagnosis technology makes it possible to detect deafness genes for children with congenital hearing impairment, and the proportion of gap junction protein beta 2 （...
关键词：GENETIC CONNEXIN26 cochlear implant rehabilitation effect 
Down-regulation of peroxisome proliferator-activated receptor γ coactivator-1α expression in fatty acid-induced pancreatic betacell apoptosis involves nuclear factor-κB pathway被引量：1
《Chinese Medical Journal》2011年第22期3657-3663,共7页HE Ting-ting CAO Xiao-pei CHEN Ru-zhu ZHU Xiao-nan WANG Xue-lan LI Yan-bing XIAO Hai-peng 
Background Pancreatic beta-cell apoptosis induced by lipotoxicity, to a large extent, contributes to the progression of type 2 diabetes. To investigate the mechanism of free fatty acid induced apoptosis, we aimed to s...
关键词：BETA-CELL apoptosis peroxisome proliferator-activated receptor 7 coactivator-1α nuclear factor-κB 
A new mutation in the thyroid hormone receptor gene of a Chinese family with resistance to thyroid hormone被引量：10
《Chinese Medical Journal》2011年第12期1835-1839,共5页DONG Qian GONG Chun-xiu GU Yi SU Chang 
Background Resistance to thyroid hormone （RTH） is a dominant inherited syndrome of reduced tissue responsiveness to thyroid hormone. It is usually due to mutations located at the ligand-binding domain and adjacent h...
关键词：resistance to thyroid hormone ＇ thyroid hormone receptor beta MUTATION 
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