云南高校图书馆联盟文献共享服务平台- BETA-CELL

BETA-CELL: 作品数：13被引量：36H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：许桂莲更多>>; 相关机构：第三军医大学首都医科大学首都医科大学附属北京友谊医院更多>>; 相关期刊：《Cell Regeneration》《Journal of Diabetes Mellitus》《World Journal of Gastroenterology》《Hepatobiliary & Pancreatic Diseases International》更多>>; 相关基金：国家重点基础研究发展计划国家自然科学基金中国博士后科学基金更多>>

Metabolically healthy obesity:Is it really healthy for type 2 diabetes mellitus?: 《World Journal of Diabetes》2022年第2期70-84,共15页Qi Wu Ming-Feng Xia Xin Gao; Metabolically healthy obese(MHO)individuals are reported to have a lower risk of developing cardiovascular diseases in comparison with individuals with metabolic syndrome.However,the association between MHO and type 2...; 关键词：Metabolically healthy obesity Type 2 diabetes Non-alcoholic fatty liver diseases Insulin resistance Low-grade inflammatory status Beta-cell dysfunction

Islet cell dysfunction in patients with chronic pancreatitis被引量：5: 《World Journal of Diabetes》2020年第7期280-292,共13页Ayan Roy Jayaprakash Sahoo Sadishkumar Kamalanathan Dukhabandhu Naik Pazhanivel Mohan Biju Pottakkat; Chronic pancreatitis(CP)is characterized by progressive inflammation and fibrosis of the pancreas that eventually leads to pancreatic exocrine and endocrine insufficiency.Diabetes in the background of CP is very diffi...; 关键词：Alpha cell BETA-CELL Chronic pancreatitis DIABETES INCRETINS Pancreatic diabetes

Long-term case study of a Wuzhishan miniature pig with diabetes被引量：2: 《Animal Models and Experimental Medicine》2020年第1期22-31,共10页Miaomiao Niu Yaqian Liu Lei Xiang Yuqiong Zhao Jifang Yuan Yunxiao Jia Xin Dai Hua Chen; The work was supported by the National Natural Science Foundation of China under Grant 31472057 and 31802021;Science and Technology Innovation Nursery Foundation of Chinese PLA General Hospital under Grant 16KMM51.; Background:Miniature pigs are attractive animal models for exploring diabetes because they are similar to humans in terms of physiological structure and metabolism.However,little is known about the complications of di...; 关键词：BETA-CELL regeneration diabetes-related COMPLICATIONS PIG

A FRET biosensor reveals free zinc deficiency in diabetic beta-cell vesicles: 《Chinese Chemical Letters》2020年第2期468-472,共5页Yi Xian Mengxuan Zhou Shangchen Han Rong Yang Yi Wang; supported by a China Postdoctoral Science Foundation-funded project(No.2017M612440)。; The concentration of free zinc within insulin-storing vesicles is important for vesicle maturity and therefore requires accurate measurement.However,common small-molecule intensity-based probes and most available gene...; 关键词：Zinc FRET Insulin BIOSENSOR Beta cell VESICLE Diabetes

Effect of Frey's procedure on islet cell function in patients with chronic calcific pancreatitis: 《Hepatobiliary & Pancreatic Diseases International》2018年第4期358-362,共5页Ritesh Kumar Jaya Prakash Sahoo Biju Pottakat Sadishkumar Kamalanathan Pazhanivel Mohan Vikram Kate Sitanshu Sekhar Kar Jayakumar Selviambigapathya; supported by Intramural research grant from Jawaharlal Institute of Postgraduate Medical Education and Research(JIPMER)(JIP/Res/Intra-DM-M.Ch/02/2014); Background: Frey’s procedure involves both drainage and resection of the pancreas in subjects with chronic calcific pancreatitis(CCP). The procedure may affect the pancreatic endocrine function after surgery. The pre...; 关键词：BETA-CELL Diabetes mellitus GLUCAGON Insulin secretion sensitivity index Matsuda index

Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival被引量：9: 《Protein & Cell》2016年第5期362-372,共11页Yaoting Deng Yurika Matsui Wenfei Pan Qiu Li Zhi-Chun Lai; Mammalian pancreatic β-cells play a pivotal role in development and glucose homeostasis through the production and secretion of insulin. Functional failure or decrease in β-cell number leads to type 2 diabetes （T2D...; 关键词：β-cell CTGF F-ACTIN free fatty acid Hipposignaling Yap1

Pancreatic fat and β-cell function in overweight/obese children with nonalcoholic fatty liver disease被引量：6: 《World Journal of Gastroenterology》2015年第15期4688-4695,共8页Lucia Pacifico Michele Di Martino Caterina Anania Gian Marco Andreoli Mario Bezzi Carlo Catalano Claudio Chiesa; Supported by Sapienza University of Rome(Progetti di Ricerca Universitaria 2011-2012); AIM: To analyze the associations of pancreatic fat with other fat depots and β-cell function in pediatric nonalcoholic fatty liver disease(NAFLD).METHODS: We examined 158 overweight/obese children and adolescents, 80...; 关键词：NONALCOHOLIC FATTY liver disease Pancreaticfat VISCERAL FAT BETA-CELL function Children

The involvement of interleukin-22 in the expression of pancreatic beta cell regenerative Reg genes被引量：2: 《Cell Regeneration》2013年第1期7-17,共11页Thomas Hill Olga Krougly Enayat Nikoopour Stacey Bellemore Edwin Lee-Chan Lynette A Fouser David J Hill Bhagirath Singh; We thank Ms.Brenda Strutt and Jessica Hill for technical help and Dr.Margery Ma from Pfizer,Cambridge,MA for anti-IL-22 antibody.We also thank Dr.Kathleen Hill,Dr.Alexander Timoshenko and Morgan Kleiber for assistance in experimental design and interpretation of the data.This work was supported by grants from the Canadian Institutes of Health Research(CIHR).; Background:In Type 1 diabetes,the insulin-producingβ-cells within the pancreatic islets of Langerhans are destroyed.We showed previously that immunotherapy with Bacillus Calmette-Guerin(BCG)or complete Freund’s adju...; 关键词：Adjuvant immunotherapy INTERLEUKIN-22 Regenerating(Reg)genes Beta-cell regeneration Type 1 diabetes

Autophagy induced by glibenclamide serves as a defense against apoptosis in INS-1 rat insulinoma cells: 《Journal of Diabetes Mellitus》2013年第3期122-128,共7页Hua Su Xingyan Liu Ling Su Li Zhang Xiangguo Liu Hong Ji Haiqin Rong; Glibenclamide, a blocker of ATP-sensitive potassium channels, has been found to induce apoptosis in some cell types, including pancreatic beta-cells. Since autophagy plays doubleedged roles in pancreatic beta-cell sur...; 关键词：GLIBENCLAMIDE Pancreatic BETA-CELL AUTOPHAGY APOPTOSIS p70 S6K

Effects of Chinese medicine Tongxinluo on hyperglycemia and beta-cell damage in streptozotocin-induced diabetic rats被引量：3: 《Chinese Medical Journal》2012年第20期3675-3680,共6页WANG Huai-qing ZOU Jun-jie ZHOU Xiang-hai JI Li-nong LIU Zhi-min; Background Oxidative stress has been implicated in the onset and progression of diabetes. Tongxinluo is a traditional Chinese medicine with potent antioxidant properties. The aim of this study was to test the hypothes...; 关键词：TONGXINLUO STREPTOZOTOCIN diabetes ＂ oxidative stress ＂ antioxidants beta-cell function

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