TONGXINLUO

作品数：23被引量：172H指数：8
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相关领域：医药卫生更多>>
相关作者：吴琳胡昊寿晓玲周忠冉张海山更多>>
相关机构：河北医科大学中山大学附属第三医院哈佛大学中国医科大学附属第一医院更多>>
相关期刊：《Chinese Medical Journal》《World Journal of Diabetes》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《中文科技期刊数据库（全文版）医药卫生》更多>>
相关基金：国家重点基础研究发展计划国家自然科学基金World Health Organization中国博士后科学基金更多>>
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Tongxinluo Activates PI3K/AKT Signaling Pathway to Inhibit Endothelial Mesenchymal Transition and Attenuate Myocardial Fibrosis after Ischemia-Reperfusion in Mice被引量：3
《Chinese Journal of Integrative Medicine》2024年第7期608-615,共8页WEI Ya-ru HOU Yun-long YIN Yu-jie LI Zhen LIU Yi HAN Ning-xin WANG Zi-xuan LIU Lu WANG Xiao-qi HAO Yuan-jie MA Kun GU Jiao-jiao JIA Zhen-hua 
Supported by the National Natural Science Foundation of China(No.81973692);Traditional Chinese Medicine Innovation Project of Hebei Province(No.223777120D);High-Level Talent Funding Program of Hebei(No.E2020100001)。
Objective To investigate the potential role of Tongxinluo(TXL)in attenuating myocardial fibrosis after myocardial ischemia-reperfusion injury(MIRI)in mice.Methods A MIRI mouse model was established by left anterior de...
关键词：myocardial fibrosis endothelial mesenchymal transition myocardial ischemia-reperfusion injury phosphatidylinositol-3-kinase/protein kinase B(PI3K/AKT)pathway 
Protective Effects and Potential Mechanism of Tongxinluo on Mice with Thromboangiitis Obliterans Induced by Sodium Laurate被引量：1
《Chinese Journal of Integrative Medicine》2023年第7期608-616,共9页GU Jiao-jiao WEI Ya-ru MA Ku WANG Xiao-qi GAO Huai-lin 
Supported by the Natural Science Foundation of Hebei Province(No.H2019106062)。
Objective To investigate the effects of Tongxinluo(TXL)on thromboangiitis obliterans(TAO)and the underlying mechanisms.Methods Ninety male C57/BL6J mice were randomly divided into 6 groups according to a random number...
关键词：TONGXINLUO thromboangitis obliterans THROMBOSIS INFLAMMATION 
Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease
《World Journal of Diabetes》2023年第3期234-254,共21页Jiao-Jiao Gu Yun-Long Hou Yi-Hui Yan Jie Li Ya-Ru Wei Kun Ma Xiao-Qi Wang Jie-Han Zhang Dan-Dong Wang Cui-Ru Li Dong-Qi Li Ling-Ling Sun Huai-Lin Gao 
Supported by The Hebei Province Natural Science Foundation,No. H2019106062;Key R&D Plan of Hebei Provincial Department of Science and Technology,No. 223777155D;Research Project of Hebei Provincial Administration of Traditional Chinese Medicine,No. 2023179
BACKGROUND Peripheral arterial disease(PAD)has become one of the leading causes of disability and death in diabetic patients.Restoring blood supply to the hindlimbs,especially by promoting arteriogenesis,is currently ...
关键词：Diabetic peripheral arterial disease ARTERIOGENESIS Endothelial cell Inflammation PYROPTOSIS 
Effect of Enalapril Maleate and folic acid tablets combined with Tongxinluo on the proliferation of aortic smooth muscle cells in rats induced by methionine
《China Medical Abstracts(Internal Medicine)》2022年第2期74-75,共2页HUANG Jianfeng 
Objective To explore the effect of enalaprilat maleate and folic acid tablets combined with Tongxinluo on methione-induced proliferation of aortic smooth muscle cells in rats.Methods The proliferation of rat aortic sm...
关键词：TABLETS AORTIC ENALAPRIL 
通心络胶囊对稳定型心绞痛的临床疗效及其对内皮细胞功能的作用分析
《中文科技期刊数据库（全文版）医药卫生》2021年第8期54-54,共1页王际冰 李明 
探讨分析通心络胶囊(Tongxinluo capsule)治疗稳定型心绞痛(stable angina pectoris SAP)的临床治疗效果及对内皮细胞功能( endothelial cells function ECsF)的影响。方法:选取2020年1月至2021年3月到我院就诊的SAP患者60例为研究对象...
关键词：TONGXINLUO CAPSULE SAP ECsF 临床疗效 
Tongxinluo Ameliorates Myocardial Ischemia-Reperfusion Injury Mainly via Activating Parkin-Mediated Mitophagy and Downregulating Ubiquitin-Proteasome System被引量：10
《Chinese Journal of Integrative Medicine》2021年第7期542-550,共9页YANG Hong-xing WANG Peng WANG Ning-ning LI Shao-dan YANG Ming-hui 
Supported by the National Basic Research Program(973 Program)of China(No.2012CB518601)。
Objective To investigate the protective effects and mechanism of Chinese herbal compound Tongxinluo Capsule(通心络胶囊,TXL)on the Parkin-mediated mitophagy and the ubiquitin-proteasome system in a rat model of myocard...
关键词：Chinese medicine MITOPHAGY ischemia-reperfusion injury PARKIN UBIQUITIN 
Early Intervention of Tongxinluo(通心络) on Right Ventricular Function Assessed by Echocardiography in Rats with Pulmonary Arterial Hypertension Induced by Monocrotaline
《Chinese Journal of Integrative Medicine》2020年第12期913-920,共8页GAO Lu LI Shao-dan ZHANG Yin LIU Yi YANG Ming-hui 
Supported by National Key Basic Research Special Foundation of China(No.2012CB518600)。
Objective:To investigate the effect of early intervention of Tongxinluo(通心络,TXL)on right ventricular function(RVF)of rats with pulmonary arterial hypertension(PAH)induced by monocrotaline(MCT).Methods:A total of 30...
关键词：TONGXINLUO early intervention pulmonary arterial hypertension right ventricular function ECHOCARDIOGRAPHY 
Observation of changes in the number of myocardial capillaries in rabbits after treatment of acute myocardial infarction by Tongxinluo superfine powder被引量：1
《Journal of Traditional Chinese Medicine》2018年第3期406-411,共6页Wu Haotian Zhang Fengshun Liu Jinyi Li Xuezhao Guo Fei Wu Yiling 
OBJECTIVE: To investigate the effects of Tongxinluo superfine powder on cardiac function, infarct size and the number of myocardial capillaries in a rabbit model of acute myocardial infarction.METHODS: A total of 32 N...
关键词：MYOCARDIAL INFARCTION MYOCARDIUM Mi-crocirculation X-Ray Microtomography Ferric chlo-ride TONGXINLUO superfine powder 
Tongxinluo Improves Apolipoprotein E-Deficient Mouse Heart Function被引量：8
《Chinese Medical Journal》2018年第5期544-552,共9页Guo-Qiang Yuan Song Gao Yong-Jian Geng Yao-Ping Tang Min-Juan Zheng Harnath S Shelat Scott Collins Han-Jing Wu Yi-Ling Wu 
Background： Our previous studies have shown that Tongxinluo （TXL）, a compound Chinese medicine, can decrease myocardial ischemia-reperfusion injury, protect capillary endothelium function, and lessen cardiac ventri...
关键词：Heart Function： Microvascular Protection：Tongxinluo 
Clinical study on the effect of Tongxinluo combined with trimetazidine on cardiac function in patients with acute ST-segment elevation myocardial infarction after percutaneous coronary intervention
《Journal of Hainan Medical University》2017年第13期75-78,共4页Qun-Xiong Fan Ji-Xian Zhao Huan-Xin Zhang Bo Li Zheng-Rong Li 
Objective:To investigate the clinical effect of Tongxinluo combined with trimetazidine on cardiac function in patients with acute ST-segment elevation myocardial infarction after percutaneous coronary intervention.Met...
关键词：TONGXINLUO TRIMETAZIDINE Acute ST-SEGMENT elevation myocardial INFARCTION PERCUTANEOUS coronary intervention Cardiac function 
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