Health Commission of Henan Province (Grant No. LHGJ20190278)。
Acute exacerbation of pulmonary heart disease(AECPHD) is life-threatening. Conventional therapy plus angiotensinconverting enzyme inhibitors(ACEI) is not always practical. Recent trials have suggested the beneficial e...
Objective To explore the effect of enalaprilat maleate and folic acid tablets combined with Tongxinluo on methione-induced proliferation of aortic smooth muscle cells in rats.Methods The proliferation of rat aortic sm...
Objective: the purpose of this study is to explore and analyze the practical effect of enalapril combined with amlodipine in the treatment of elderly patients with hypertension, so as to provide reference for relevant...
Objecrive:To explore the effect of enalapril combined with hydroch1orothiazide and indapamide on hypertension and heart failure.Methods:8o patients with hypertension and heart failure admitted to our hospitail from Ja...
The objective of this study was to analyze the efficacy of combined drug therapy for elderly patients with coronary heart disease and hypertension.66 elderly patients with coronary heart disease and hypertension were ...
supported by National Natural Science Foundation of China(No.81641058)
Background The incidence of leg edema caused by calcium channel blockers(CCB) is so high, some studies tried combination with angiotension converting enzyme inhibitors(ACEI) or diuretics to overcome this problem.H...
Objective:To study the in vitro interactions of ibuprofen with enalapril.Methods:In this study,we investigated synergistic effect of angiotensin-converting enzyme inhibitor(enalapril)with commonly used nonsteroidal an...
Supported by A research grant from Abbott Pharmaceutical,United States
AIM: To investigate the protective effect of paricalcitol and enalapril on renal inflammation and oxidative stress in Apo E-knock out mice. METHODS: Animals treated for 4 mo as group(1) Apo E-knock out plus vehicle, g...
Aim: RhoA/ROCK signaling plays an important role in diabetic nephropathy, and ROCK inhibitor fasudil exerts nephroprotection in experimental diabetic nephropathy. In this study we investigated the molecular mechanism...
National Natural Science Foundation of China(Grant No.81102499);supported by Hunan Science and Technology Project(Grant No.2011SK3261,Changsha,China)
To compare the pharmacokinetics properties of enalapril-felodipine sustained-release tablet with enalapril and felodipine in the two reference formulations in Chinese healthy volunteers, the study was designed to a ra...