BIAPENEM

作品数：7被引量：22H指数：2
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相关领域：医药卫生更多>>
相关作者：王楠朱旭何晓静李岭张斗胜更多>>
相关机构：北京协和医学院东北大学中国药品生物制品检定所中国医科大学更多>>
相关期刊：《世界临床药物》《Journal of Chinese Pharmaceutical Sciences》《国外医药（抗生素分册）》《Biomedical and Environmental Sciences》更多>>
相关基金：国家自然科学基金更多>>
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Activities of Biapenem against Mycobacterium tuberculosis in Macrophages and Mice被引量：1
《Biomedical and Environmental Sciences》2019年第4期235-241,共7页GUO Zhen Yong ZHAO Wei Jie ZHENG Mei Qin LIU Shuo YAN Chen Xia LI Peng XU Shao Fa 
supported by the Beijing Medical Award Foundation [YJHYXKYJJ-104]
Objective To assess the activities of biapenem against multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis. Methods Biapenem/clavulanate(BP/CL) was evaluated for in vitro activity against Myc...
关键词：BIAPENEM CLAVULANATE MULTIDRUG resistant EXTENSIVE DRUG-RESISTANT MYCOBACTERIUM tuberculosis Activity Macrophage Synergy 
Establishment of an HPLC method for the analysis of biapenem and its impurities被引量：1
《Journal of Chinese Pharmaceutical Sciences》2011年第2X期171-180,共10页王楠 李春凤 张斗胜 胡昌勤 
National Key New Drug R&D Program Foundation of China(Grant No.2009ZX09313-027).
An HPLC method for routine quality control of biapenem was established.A Dikma Diamonsil C_(18) column(250mm×4.6 mm,5μm) was used with diode array detection and single wavelength detection at 220 nm.The mobile phase...
关键词：BIAPENEM HPLC-DAD Two-dimensional chromatographic spectral correlative map Identification IMPURITIES 
Establishment of an HPLC method for the analysis of biapenem and its impurities被引量：8
《Journal of Chinese Pharmaceutical Sciences》2011年第2期171-180,共10页Nan Wang Chun-Feng Li Dou-Sheng Zhang Chang-Qin Hu 
Foundation item： National Key New Drag R＆D Program Foundation of China （Grant No. 2009ZX09313-027）.
An HPLC method for routine quality control of biapenem was established. A Dikma Diamonsil Cls column （250 mm× 4.6 mm, 5 μm） was used with diode array detection and single wavelength detection at 220 mm. The mobile...
关键词：BIAPENEM HPLC-DAD Two-dimensional chromatographic spectral correlative map Identification IMPURITIES 
HPLC-UV method with solid-phase extraction for the quantitative determination of biapenem in human plasma and its application in pharmacokinetic study被引量：1
《Journal of Chinese Pharmaceutical Sciences》2011年第1期70-76,共7页朱旭 孙亚欣 何晓静 邱枫 李岭 肇丽梅 
National Natural Science Foundation of China (Grant No.30973597)
Biapenem, a new parenteral carbapenem, has been widely used for treating bacterial infections. A simple, effective and accurate method based on solid-phase extraction （SPE） and HPLC was developed for the quantitativ...
关键词：BIAPENEM Solid-phase extraction High-performance liquid chromatography Pharmacokinetic study 
Determination of biapenem in human plasma and urine by a simple HPLC method for its pharmacokinetics study
《Journal of Chinese Pharmaceutical Sciences》2009年第2期177-182,共6页武晓捷 郁继诚 张菁 曹国英 施耀国 张婴元 
A simple high-performance liquid chromatography （HPLC） method was established and subsequently used to study the pharmacokinetics of biapenem in healthy volunteers. Chromatography separation was carried out using a ...
关键词：BIAPENEM High performance liquid chromatography PHARMACOKINETICS 
新型抗菌药物比阿培南(biapenem)被引量：10
《世界临床药物》2003年第9期572-573,共2页崔银珠 
关键词：比阿培南 抗菌药物 药理作用 临床评价 不良反应 
Biapenem对革兰阳性和阴性菌的体外抗菌活性被引量：1
《国外医药（抗生素分册）》1995年第1期45-46,共2页陈纯 
过去几年里,开发了许多广谱抗生素,如青霉素类、头孢菌素类,以及最近报道的碳青霉烯类。亚胺培南(IP)是碳青霉烯类中唯一已用于临床的药物,抗菌谱极广,抗菌活性强,对革兰阳性和阴性菌、需氧和厌氧菌包括多重耐药或产β-内酰胺酶的细菌...
关键词：BIAPENEM 革兰阳性菌 革兰阳性菌 体外 抗菌活性 
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