funded by the Central to guide local scientific and Technological Development(ZYYDDFFZZJ-1);Natural Science Foundation of Gansu Province,China(No.18JR3RA052);Lanzhou Talent Innovation and Entrepreneurship Project Task Contract(No.2016-RC-56);Gansu Da Vinci Robot High-End Diagnosis and Treatment Team Construction Project,and Gansu Provincial Youth Science and Technology Fund Program(20JR10RA415);National Key Research and Development Program(No.2018YFC1311500).
B and T-lymphocyte attenuator(BTLA)plays an immunosuppressive role by inhibiting T-and B-cell functions.BTLA is associated with a variety of diseases,especially cancer immunity.However,the function of BTLA in various ...
supported by the National Natural Science Foundation of China(82020108021);the Chongqing Special Project for Academicians(cstc2020yszx-jcyj X0004);the Project of the Trauma;Burns and Combined Injury State Key Laboratory(SKLYQ201901,SKLKF201802);the Training Plan of the Innovation Ability of Military Medical Frontier Research(2019CXJSB014,2019CXJSB004);the Project of the Science and Technology Fund of Guizhou Provincial Department of Health(gzwjkj2020-1-106)。
Sepsis,defined as life-threatening organ failure caused by a dysregulated host response to severe infection,is a major cause of death among intensive care unit patients.Therapies targeting on immunomodulatory is a new...
目的研究B、T淋巴细胞衰减因子(B and T lymphocyte attenuator,BTLA)及其配体疱疹病毒进入中介体(herpesvirus entry mediator,HVEM)在肺结核患者CD4^(+)CD25^(+)CD127^(low)调节性T细胞(CD4^(+)CD25^(+)CD127^(low)Treg)中的表达及其...
B、T淋巴细胞弱化因子(B and T lymphocyte attenuator, BTLA)是21世纪初发现的负向共刺激分子成员,是Ig超家族的Ⅰ型跨膜蛋白,其配体为肿瘤坏死因子超家族的疱疹病毒侵入介体(herpesvirus entry mediator, HVEM)。BTLA调节γδT细胞和...