There is a clerical error in the main text.Published:Among these cells,only HcC827 cells showed significantly high mRNA levels of c-FLiP and FoxM1,while only Hi975 cells showed significantly low mRNA levels of c-FLIP ...
supported by National Natural Science Foundation of China (No.81872922 and 82073683).
Excessive apoptosis of intestinal epithelial cell(IEC)is a crucial cause of disrupted epithelium homeostasis,leading to the pathogenesis of ulcerative colitis(UC).The regulation of Takeda G protein-coupled receptor-5(...
Resistance to anticancer agents and apoptosis results in cancer relapse and is associated with cancer mortality.Substantial data have provided convincing evidence establishing that human cancers emerge from cancer ste...
the National Natural Science Foundation of China(81702934);CAMS Innovation Fund for Medical Sciences(CIFMS,2019-12M-1-003,2021-12M-1-030);Beijing Natural Science Foundation(7202132,7192041).
The forkhead box M1(FoxM1)protein,a transcription factor,plays critical roles in regulating tumor growth and drug resistance,while cellular FLICE-inhibitory protein(c-FLIP),an anti-apoptotic regulator,is involved in t...