CANCER_CELLS

作品数：433被引量：1403H指数：15
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Biological effects of radiation on cancer cells被引量：7
《Military Medical Research》2018年第4期350-360,共11页Jin-Song Wang Hai-Juan Wang Hai-Li Qian 
financially supported by grants from the CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2016-I2M-1-001);the National Basic Research Program of China(973 Program)(No.2015CB553904);the National Natural Science Foundation of China(No.81372158,81372159,81572842,81672459);the Independent Issue of State Key Laboratory of Molecular Oncology(No.SKL-2017-16)
With the development of radiotherapeutic oncology, computer technology and medical imaging technology, radiation therapy has made great progress. Research on the impact and the specific mechanism of radiation on tumor...
关键词：RADIATION CANCER CELLS BIOLOGICAL features Combinational THERAPY 
Apoptotic Signal Pathways and Regulatory Mechanisms of Cancer Cells Induced by IL-24
《Wuhan University Journal of Natural Sciences》2016年第6期519-530,共12页LIU Huilin CHEN Jiaojiao JIANG Xingyan WANG Tao XIE Xiaoyuan HU Hui YU Fang WANG Xingzhi FAN Handong 
Supported by the National Program on Key Basic Research Project(973 Program)(2012CB518900);the National Natural Science Foundation of China(31160240,31260621);the 12th Five Years Key Programs for Science and Technology Development of China(2012ZX10002006);the Hangzhou Normal University Supporting Project(PE13002004042);the Natural Science Foundation of China of Jiangxi(20114BAB204016)
The melanoma differentiation-associated gene-7（mda-7）,IL-24,has the specific functions that induce cancer cell apoptosis without doing harm to normal cells. We systematically review the apoptotic signal pathways and...
关键词：apoptosis IL-24 signal pathway tumor 
Anticancer strategies based on the metabolic profile of tumor cells： therapeutic targeting of the Warburg effect被引量：10
《Acta Pharmacologica Sinica》2016年第8期1013-1019,共7页Xi-sha CHEN Lan-ya LI Yi-di GUAN Jin-ming YANG Yan CHENG 
This work was supported by grants from the National Basic Research Program of China （973 Program, 2015CB910700） （Yan CHENG） and the National Natural Science Foundation of China （81422051, 81472593, and 31401208） （Yan CHENG）.
Tumor cells rely mainly on glycolysis for energy production even in the presence of sufficient oxygen, a phenomenon termed the Warburg effect, which is the most outstanding characteristic of energy metabolism in cance...
关键词：glycolysis cancer cells cancer cells metabolism Warburg effect anticancer strategy 
A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity被引量：4
《Signal Transduction and Targeted Therapy》2016年第1期31-40,共10页Hongwei Tian Gang Shi Qin Wang Yiming Li Qianmei Yang Chunlei Li Guoyou Yang Min Wu Qian Xie Shuang Zhang Yang Yang Rong Xiang Dechao Yu Yuquan Wei Hongxin Deng 
This work was supported by The National Key Basic Research Program(973 Program)of China(2012CB917104 and 2013CB967201);National Natural Science Foundation of China Program grant(No:81372445);National Institute of Health grant(AI109317-01A1 and AI109373-01).
Tumor escape from immune-mediated destruction has been associated with immunosuppressive mechanisms that inhibit T-cell activation.A promising strategy for cancer immunotherapy is to disrupt key pathways regulating im...
关键词：VACCINE immunity simultaneous 
Influence of Osteopontin Short Hairpin RNA on the Proliferation and Invasion of Human Renal Cancer Cells被引量：2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2010年第1期61-68,共8页柳昊 陈安民 郭风劲 袁林 
supported by a grant from the Major State Basic Research Development Program of China(973 Program)(No.2002CB513100)
The influence of short hairpin RNA(shRNA)-mediated osteopontin(OPN)gene silencing on the proliferation and invasion of human renal cancer ACHN cells was investigated.Four types of OPN shRNA recombinant plasmids were c...
关键词：OSTEOPONTIN short hairpin RNA RNA interference human renal cancer cells 
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