Qu and Li emphasize a fundamental aspect of metabolic dysfunction-associated fatty liver disease in their manuscript,focusing on the critical need for noninvasive diagnostic tools to improve risk stratification and pr...
supported by Chongqing Municipal Natural Science Foundation (CSTB2022NSCQ-MSX1366);National Natural Science Foundation of China (81702182,81874087);Chongqing Outstanding Young Talent Supporting Program (cstc2024ycjhbgzxm0031);the Special Project for Talent Development of Xinqiao Hospital (2022XKRC006)。
Intervertebral disc degeneration(IDD)is a major cause of discogenic pain,and is attributed to the dysfunction of nucleus pulposus,annulus fibrosus,and cartilaginous endplate(CEP).Osteopontin(OPN),a glycoprotein,is hig...
supported by the National Research Foundation of the Republic of Korea 2018R1D1A3B07047960;the Soonchunhyang University Research Fund(to SSY).
Diseases like Alzheimer’s and Parkinson’s diseases are defined by inflammation and the damage neurons undergo due to oxidative stress. A primary reactive oxygen species contributor in the central nervous system, NAD...
Objective:To investigate the effect of allicin on the formation of kidney stones in rats by regulating the expression of osteopontin(OPN)and nuclear factor-κB(NF-κB)signaling pathway.Methods:A total of 50 healthy ad...
BACKGROUND Gastric cancer(GC)is one of the most common malignant tumors.Osteopontin(OPN)is thought to be closely related to the occurrence,metastasis and prognosis of many types of tumors.AIM To investigate the effect...
supported by the Special funds for the con-struction of innovative provinces in Hunan Province(No.2020RC3058);the Natural Science Foundation of Hunan(No.2022JJ40802,2022JJ30075);the China Post-doctoral Science Foundation(No.2022M713525).
Osteoarthritis(OA)is a chronic debilitating joint disease,characterized by degen-eration of the cartilage and loss of the cartilage matrix,and it is clinically manifested as joint pain.Osteopontin(OPN)is a glycoprotei...
Correction to:Acta Pharmacologica Sinica https://doi.org/10.1038/aps.2015.37,published online 15 June 2015 The authors are very sorry for two mistakes in the figures:the images of western blot showing PPARαphosphoryl...
supported by National Natural Science Foundation of China grants (81760089,82160094 to MJ,82060112 to LD);Jiangxi Provincial Department of Science and Technology,China (20202BAB206087 to MJ).
Background and Aims:Osteopontin(OPN)is reported to be associated with the pathogenesis of nonalcoholic fatty liver disease(NAFLD).However,the function of OPN in NAFLD is still inconclusive.Therefore,our aim in this st...
supported by grants from the Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition(17dz2272000);the National Natural Science Foundation of China-Key Program(81630039)。
Objective:This study explored the content and change trend of osteopontin(OPN)in breast milk and analyzed the relationship between OPN in breast milk and maternal body composition.Methods:Breast-feeding mothers were r...