OSTEOPONTIN

作品数:133被引量:424H指数:10
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相关领域:医药卫生更多>>
相关作者:王鹏李婷蒋海鹰周建华王金胜更多>>
相关机构:中南大学南方医科大学中国医科大学首都医科大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金广东省自然科学基金更多>>
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Inflammatory biomarkers as cost-effective predictive tools in metabolic dysfunction-associated fatty liver disease
《World Journal of Gastroenterology》2024年第47期5086-5091,共6页Davide Ramoni Luca Liberale Fabrizio Montecucco 
Qu and Li emphasize a fundamental aspect of metabolic dysfunction-associated fatty liver disease in their manuscript,focusing on the critical need for noninvasive diagnostic tools to improve risk stratification and pr...
关键词:ADIPOKINES Cardiometabolic risk assessment Inflammatory biomarkers Metabolic dysfunction-associated fatty liver disease Metabolic syndrome OSTEOPONTIN 
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome
《Bone Research》2024年第4期846-862,共17页Yanqiu Wang Wanqian Zhang Yi Yang Jinghao Qin Ruoyu Wang Shuai Wang Wenjuan Fu Qin Niu Yanxia Wang Changqing Li Hongli Li Yue Zhou Minghan Liu 
supported by Chongqing Municipal Natural Science Foundation (CSTB2022NSCQ-MSX1366);National Natural Science Foundation of China (81702182,81874087);Chongqing Outstanding Young Talent Supporting Program (cstc2024ycjhbgzxm0031);the Special Project for Talent Development of Xinqiao Hospital (2022XKRC006)。
Intervertebral disc degeneration(IDD)is a major cause of discogenic pain,and is attributed to the dysfunction of nucleus pulposus,annulus fibrosus,and cartilaginous endplate(CEP).Osteopontin(OPN),a glycoprotein,is hig...
关键词:NLRP3 DEGENERATION homeostasis 
NADPH oxidase 4(NOX4)as a biomarker and therapeutic target in neurodegenerative diseases被引量:2
《Neural Regeneration Research》2024年第9期1961-1966,共6页Napissara Boonpraman Sun Shin Yi 
supported by the National Research Foundation of the Republic of Korea 2018R1D1A3B07047960;the Soonchunhyang University Research Fund(to SSY).
Diseases like Alzheimer’s and Parkinson’s diseases are defined by inflammation and the damage neurons undergo due to oxidative stress. A primary reactive oxygen species contributor in the central nervous system, NAD...
关键词:Alzheimer’s disease ASTROCYTES mitochondrial dysfunction MYELOPEROXIDASE NADPH oxidase 4 NADPH oxidase 4 inhibitors neurodegenerative diseases OSTEOPONTIN Parkinson’s disease reactive oxygen species 
Effect of Allicin on the Formation of Kidney Stones in Rats by Regulating the Expression of OPN and NF-κB Signaling Pathway
《Chinese Journal of Biomedical Engineering(English Edition)》2024年第2期76-84,共9页TU Tao ZHAO Li-wen WU Qin-fu 
Objective:To investigate the effect of allicin on the formation of kidney stones in rats by regulating the expression of osteopontin(OPN)and nuclear factor-κB(NF-κB)signaling pathway.Methods:A total of 50 healthy ad...
关键词:kidney stone ALLICIN OSTEOPONTIN nuclear factor-κB signaling pathway 
Corrigendum: Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease
《Journal of Clinical and Translational Hepatology》2024年第1期119-121,共3页
Osteopontin promotes gastric cancer progression via phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway
《World Journal of Gastrointestinal Oncology》2023年第9期1544-1555,共12页Yue-Chao Qin Xin Yan Xiao-Lin Yuan Wei-Wei Yu Fan-Jie Qu 
BACKGROUND Gastric cancer(GC)is one of the most common malignant tumors.Osteopontin(OPN)is thought to be closely related to the occurrence,metastasis and prognosis of many types of tumors.AIM To investigate the effect...
关键词:OSTEOPONTIN Proliferation INVASION Migration Gastric cancer Phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway 
Osteopontin(OPN)alleviates the progression of osteoarthritis by promoting the anabolism of chondrocytes
《Genes & Diseases》2023年第4期1714-1725,共12页Wei Luo Zili Lin Yuhao Yuan Ziyi Wu Wei Zhong Qing Liu 
supported by the Special funds for the con-struction of innovative provinces in Hunan Province(No.2020RC3058);the Natural Science Foundation of Hunan(No.2022JJ40802,2022JJ30075);the China Post-doctoral Science Foundation(No.2022M713525).
Osteoarthritis(OA)is a chronic debilitating joint disease,characterized by degen-eration of the cartilage and loss of the cartilage matrix,and it is clinically manifested as joint pain.Osteopontin(OPN)is a glycoprotei...
关键词:Cartilage degeneration CD44 Hyaluronic acid OSTEOARTHRITIS OSTEOPONTIN 
Author Correction:Wogonin suppresses osteopontin expression in adipocytes by activating PPARα
《Acta Pharmacologica Sinica》2023年第6期I0001-I0001,共1页Ye-min Zhang Ming-xin Li Zhao Tang Chang-hua Wang 
Correction to:Acta Pharmacologica Sinica https://doi.org/10.1038/aps.2015.37,published online 15 June 2015 The authors are very sorry for two mistakes in the figures:the images of western blot showing PPARαphosphoryl...
关键词:PPARΑ process. submission 
Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease被引量:2
《Journal of Clinical and Translational Hepatology》2023年第2期273-283,共11页Zhihao Xu Feiyang Xi Xinxin Deng Yuqi Ni Changqin Pu Dan Wang Weiming Lou Xufang Zeng Ning Su Chen Chen Ziqiang Zeng Libin Deng Meixiu Jiang 
supported by National Natural Science Foundation of China grants (81760089,82160094 to MJ,82060112 to LD);Jiangxi Provincial Department of Science and Technology,China (20202BAB206087 to MJ).
Background and Aims:Osteopontin(OPN)is reported to be associated with the pathogenesis of nonalcoholic fatty liver disease(NAFLD).However,the function of OPN in NAFLD is still inconclusive.Therefore,our aim in this st...
关键词:OPN NAFLD Macrophage M1 polarization HMGB1 JAK1/STAT1 signaling 
The levels of osteopontin in human milk of Chinese mothers and its associations with maternal body composition被引量:2
《Food Science and Human Wellness》2022年第5期1419-1427,共9页Huijuan Ruan Qingya Tang Xuan Zhao Yajie Zhang Xuelin Zhao Yi Xiang Wei Geng Yi Feng Wei Cai 
supported by grants from the Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition(17dz2272000);the National Natural Science Foundation of China-Key Program(81630039)。
Objective:This study explored the content and change trend of osteopontin(OPN)in breast milk and analyzed the relationship between OPN in breast milk and maternal body composition.Methods:Breast-feeding mothers were r...
关键词:OSTEOPONTIN Human milk Body composition BREASTFEEDING 
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