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Chrysophanol Induces Cell Death and Inhibits Invasiveness through Alteration of Calcium Levels in HepG2 Human Liver Cancer Cells: 《Chinese Journal of Integrative Medicine》2025年第5期434-440,共7页CHEN Shu-chao CHEN Qiao-wen KO Chih-yuan; Supported by Academic Funding from the Second Affiliated Hospital of Fujian Medical University(Serial No.BS201902);Quanzhou Science and Technology Project(No.2020N090S,the Malignant Tumor Clinical Medicine Research Center,Quanzhou City,Fujian Province,China)。; Objective:To investigate the effect of chrysophanol,a phytochemical derived from Radix et Rhizoma Rhei on HepG2 liver cancer cells.Methods:HepG2 cell line was treated with different concentrations chrysophanol(0-100μ...; 关键词：apoptosis calcium CHRYSOPHANOL liver cancer mitochondrial membrane potential Radix et Rhizoma Rhei Chinese medicine

Effect of terahertz radiation on cells and cellular structures: 《Frontiers of Optoelectronics》2025年第1期21-51,共31页A.P.Rytik V.V.Tuchin; The paper presents the results of modern research on the effects of electromagnetic terahertz radiation in the frequency range 0.5-100 THz at different levels of power density and exposure time on the viability of nor...; 关键词：Electromagnetic radiation Terahertz radiation Biological effects Living cell Cancer cells

Plasma Technology:Unlocking a New Path for Precise Elimination of Cancer Cells: 《Proceedings of Anticancer Research》2025年第1期128-134,共7页Jie Bai; This paper systematically elucidates the application of plasma technology in cancer treatment,including its principles,case studies,comparative advantages over traditional methods,challenges,and countermeasures.Plasma...; 关键词：Plasma technology Cancer treatment PRECISION Side effects CHALLENGES

Loss of Arhgap39 facilitates cell migration and invasion in murine hepatocellular cancer cells: 《Oncology Research》2025年第2期493-503,共11页HUNG-WEI LIN PEI YU LEE YU-SHIUAN CHANG MAU-SUN CHANG; supported by Academia Sinica(#20020)to MSC.; Background:Rho GTPases are essential regulators for cellular movement and intracellular membrane trafficking.Their enzymatic activities fluctuate between active GTP-bound and inactive GDP-bound states regulated by GTP...; 关键词：Arhgap39 Hepa1-6 Hepa-1c1c7 INVASION

Effects of short-and long-term exercise training on cancer cells in vitro:Insights into the mechanistic associations: 《Journal of Sport and Health Science》2025年第1期73-83,共11页Francesco Bettariga Dennis R.Taaffe Daniel A.Galvão Robert U.Newton; Exercise is a therapeutic approach in cancer treatment,providing several benefits.Moreover,exercise is associated with a reduced risk for developing a range of cancers and for their recurrence,as well as with improvin...; 关键词：Resistance training Aerobic training CYTOKINES HORMONES Cancer cells

A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway: 《Acta Pharmaceutica Sinica B》2025年第2期991-1006,共16页Ying Hou Bingling Zhong Lin Zhao Heng Wang Yanyan Zhu Xianzhe Wang Haoyi Zheng Jie Yu Guokai Liu Xin Wang Jose M.Martin-Garcia Xiuping Chen; supported by the Science and Technology Development Fund,Macao S.A.R(FDCT)(0070/2022/A2,005/2023/SKL,China);the National Natural Science Foundation of China(82173848);the Research Fund of University of Macao(MYRG2020-00053-ICMS,MYRG-GRG2023-00072-ICMS-UMDF,China);the Ministry of Education Frontiers Science Centre for Precision Oncology,University of Macao(SP2023-00001-FSCPO,China).; Human NAD(P)H:quinone oxidoreductase 1(NQO1)is a flavoenzyme expressed at high levels in multiple solid tumors,making it an attractive target for anticancer drugs.Bioactivatable drugs targeting NQO1,such asβ-lapacho...; 关键词：NQO1 CRYPTOTANSHINONE Iron Ferroptosis NADþdepletion CALCIUM Targeted therapy Cancer

Research advancements in nanoparticles and cell-based drug delivery systems for the targeted killing of cancer cells: 《Oncology Research》2025年第1期27-44,共18页MERYEM A.ABDESSALEM SIRIN A.ADHAM; Nanotechnology in cancer therapy has significantly advanced treatment precision,effectiveness,and safety,improving patient outcomes and personalized care.Engineered smart nanoparticles and cell-based therapies are des...; 关键词：Drug delivery Cancer NANOPARTICLES Liposomes Micelles Combination therapies Targeted therapy Precision medicine Tumor microenvironment(TME)

Plasma Combined with Drugs:Synergistic Mechanisms for Eliminating Cancer Cells: 《Journal of Clinical and Nursing Research》2025年第1期243-248,共6页Jie Bai; With the continuous advancement of cancer treatment methods, plasma combined with drug therapy has garnered widespread attention as an emerging therapeutic strategy. This paper elaborates on the generation and charact...; 关键词：PLASMA Anticancer drugs SYNERGY Enhancement mechanisms

Analyzing the Cytotoxic and Genetic Impact of Datura stramonium Extract on MCF7 and HT29 Cancer Cells:A Metabolite and Gene Expression Study: 《Phyton-International Journal of Experimental Botany》2025年第1期181-198,共18页Fayez Althobaiti Hadeer Darwish Raghad Alruqayb Saqer S.Alotaibi Fahad E.Alharthi Ibrahim Jafri Sarah Awwadh Altalhi Ghadi Alsharif Hussam Awwadh E Althagafi Hesham Noureldeen Sarah Alharthi Jawaher Albaqami Najla Amin T.Al Kashgry Ahmed Noureldeen; Taif University,Saudi Arabia,Project No.(TU-DSPP-2024-74).; The interest in using the Datura stramonium plant is due to its natural products,which are used in many pharmaceutical industries.The objective of the current study was to assess the therapeutic and cytotoxic effects ...; 关键词：Datura stramonium secondary metabolites GC-MS analysis CYTOTOXICITY breast and colon cancer cell lines MTT assay

BIBR1532 inhibits proliferation and metastasis of esophageal squamous cancer cells by inducing telomere dysregulation: 《World Journal of Gastrointestinal Oncology》2025年第1期214-225,共12页Qin Wang Qing-Rong Li Lei Xu Zi-Chun Yuan Xiao Liu Mao-Ju Tang Man Luo Xiao-Wu Zhong Qiang Ma Xiao-Lan Guo; Supported by the Scientific Research Development Plan Project or the Scientific Research Foundation for Advanced Talents,Affiliated Hospital of North Sichuan Medical College,No.2023MPZK017,No.2023ZD001,No.2023-2ZD002,and No.2023GC009;Science and Technology Support Program of Nanchong,No.22SXQT0001;Youth Medical Innovation Research Project,or Medical Research Project of Sichuan Province,No.Q23047 and No.S23020;Development of a Scientific Research Plan for the Doctoral Scientific Research Foundation of the North Sichuan Medical College,No.CBY22-ZDA03.; BACKGROUND Esophageal squamous cell carcinoma(ESCC)is a malignant tumor with high morbidity and mortality,and easy to develop resistance to chemotherapeutic agents.Telomeres are DNA-protein complexes located at the te...; 关键词：Esophageal squamous cell carcinoma BIBR1532 Human telomerase reverse transcriptase DNA damage response Telomere-binding proteins

CANCER_CELLS