funded by the National Natural Science Foundation of China(Grant Nos.:82222059,82173416,and 81930087).
Vitiligo is an immune memory skin disease.T-cell factor 1(TCF1)is essential for maintaining the memory Tcell pool.There is an urgent need to investigate the characteristics of peripheral memory T-cell profile and TCF1...
supported by the National Natural Science Foundations of China (Nos. 81972532, 81991500, 82101017, 81902778, and 81500864);Guangdong Basic and Applied Basic Research Foundation (2020A1515110741)
The heterogeneity of exhausted T cells(Tex)is a critical determinant of immune checkpoint blockade therapy efficacy.However,few studies have explored exhausted T cell subpopulations in human cancers.In the present stu...
supported by the National Key R&D Program of China(2017YFAO105803);the general program of the National Natural Science Foundation of China(81770826);the Science and Technology Plan Projects of Guangdong Province(2019B020227003);the Key Special Projects of Medical and Health of Guangzhou City(202007040003);the 5010 Clinical Research Projects of Sun Yatsen University(2015015).
Type 1 diabetes mellitus(T1D)is a chronic autoimmune condition in which the immune system destroys insulin-producing pancreatic β cells.In addition to well-established pathogenic effector T cells,regulatory T cells(T...