Supported by Key Research&Development Program of Shaanxi Province,No.2021SF-221.
BACKGROUND Esophageal squamous papilloma(ESP)is a rare benign tumor of the esophagus,typically characterized by an exophytic and warty appearance,with a diameter of less than 5 mm.Endoscopic resection is considered th...
All data and materials are available in the article upon reasonable request to the corresponding author.Foundations:Supported by the National Natural Science Foundation of China(No.82070934;No.82171025).
AIM:To investigate the pathological features of ocular surface squamous neoplasia(OSSN)and evaluate the synergistic therapeutic effects of interferon-α2b(IFNα2b)and 5-fluorouracil(5-FU)on cellular proliferation,migr...
Supported by the National Key Research and Development Program of China,No.2023YFC2413800;the Taishan Scholars Program of Shandong Province,No.tsqn202306344;the National Natural Science Foundation of China,No.82270580 and No.82070552.
BACKGROUND Early detection of esophageal squamous neoplasms(ESN)is essential for improving patient prognosis.Optical diagnosis of ESN remains challenging.Probebased confocal laser endomicroscopy(pCLE)enables accurate ...
supported by the Science and Technology Projects of Jilin Provincial Department of Science and Technology(Grant/Award Numbers:20240305037YY);National Key Research and Development Program of China(2021YFC2400603);the Joint Funds of the National Natural Science Foundation of China(Grant No.U23A20269);the Jilin University young teachers and students cross-disciplinary training project(Grant No.2023-JCXK-08,2024-JCXK-07)。
Tongue squamous cell carcinoma(TSCC)is a prevalent malignancy that afflicts the head and neck area and presents a high incidence of metastasis and invasion.Accurate diagnosis and effective treatment are essential for ...
supported by the National Natural Science Foundation of China (82170108, 81700092, 81871889, 82072586, 81630071);the Clinical Research Projects in Health industry of Shanghai Municipal Health Commission (202340017);the Foundation of the Center for Medical and Engineering Interdisciplinary Innovation, University of Shanghai for Science and Technology (2023GD-XK08Z);the National Youth Talent (to Z. Wang);Basic Research Foundation of Shanghai Chest Hospital (2020YNJCM05);the National Key Research and Development Project of China (2022YFC2505004, 2022YFC2505000);CAMS Innovation Fund for Medical Sciences (2021-1-I2M-012);CAMS Key lab of translational research on lung cancer (2018PT31035);Beijing Natural Science Foundation (7212084)
In non-small cell lung cancers,the non-squamous and squamous subtypes(nsqNSCLC and sqNSCLC)exhibit disparities in pathophysiology,tumor immunology,and potential genomic correlates affecting responses to immune checkpo...
Supported by the 135 High-end Talent Project of West China Hospital,Sichuan University,No.ZYDG23029.
BACKGROUND Recent advancements in artificial intelligence(AI)have significantly enhanced the capabilities of endoscopic-assisted diagnosis for gastrointestinal diseases.AI has shown great promise in clinical practice,...
Supported by the Scientific Research Development Plan Project or the Scientific Research Foundation for Advanced Talents,Affiliated Hospital of North Sichuan Medical College,No.2023MPZK017,No.2023ZD001,No.2023-2ZD002,and No.2023GC009;Science and Technology Support Program of Nanchong,No.22SXQT0001;Youth Medical Innovation Research Project,or Medical Research Project of Sichuan Province,No.Q23047 and No.S23020;Development of a Scientific Research Plan for the Doctoral Scientific Research Foundation of the North Sichuan Medical College,No.CBY22-ZDA03.
BACKGROUND Esophageal squamous cell carcinoma(ESCC)is a malignant tumor with high morbidity and mortality,and easy to develop resistance to chemotherapeutic agents.Telomeres are DNA-protein complexes located at the te...
Objective:Although neck dissection has evolved to become an integral part of the surgical armamentarium for managing head and neck cancers,the manner in which the procedure has reached its present state is worth revis...
supported by the grants from the Hainan Provincial Natural Science Foundation of China(Nos.820MS141,822RC831,822QN300,and 822RC649);the National Natural Science Foundation of China(Nos.82104057,82360504,and 82203206);the Hainan University Collaborative Innovation Center Research Fund(No.XTCX2022JKB01);the Hainan“Nanhai New Star”Project(No.202309009).
Head and neck cancer(HNC)is one of the most common types of malignant cancer worldwide.These cancers originate in the oral cavity,oropharynx,larynx,hypopharynx,nasopharynx and sinonasal tract.The most common HNC type ...
National Natural Science Foundation of China(82170971,82373187and 82002888);Fundamental Research Funds for the Central Universities(YJ201987);Sichuan Science and Technology Program(2021ZYD0090 and 2022YFS0207);Scientific Research Foundation,West China Hospital of Stomatology Sichuan University(QDJF2019-3 and RD-03-202110);CAMS Innovation Fund for Medical Sciences(CIFMS,2019-I2M-5-004)。
Oral squamous cell carcinoma(OSCC)associated pain commonly predicts adverse events among patients.This clinical feature indicates the engagement of nociceptors on sensory neurons during the development of malignancy.H...