云南高校图书馆联盟文献共享服务平台- CLEAVAGE

CLEAVAGE: 作品数：348被引量：749H指数：13; 导出分析报告; 相关领域：理学医药卫生更多>>; 相关作者：胡岳华高志勇孙伟刘晓文孙萌更多>>; 相关机构：中南大学华东师范大学杭州师范大学北京化工大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划天津市自然科学基金中国博士后科学基金更多>>

Copper-catalyzed C–C bond cleavage coupling with C≡N bond formation toward mild synthesis of lignin-based benzonitriles: 《Journal of Environmental Sciences》2025年第5期505-515,共11页Qi Luo Shenglong Tian Qian Qiang Fei song Wentao Su Haiyan He Qingda An Changzhi Li; supported by the National Key R&D Program of China(No.2023YFA1507902);the National Natural Science Foundation of China(Nos.21721004 and 21878288);the science and technology bureau of Dalian city(No.2021RT04);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB17020100).; N-participated lignin depolymerization is of great importance for the transformation of waste lignin into value-added chemicals.The vast majority of developed strategies employ organic amines as nitrogen source,and co...; 关键词：LIGNIN β-O-4 model compounds Benzonitrile derivatives Copper catalyst Mild conditions

The novel BCL-2/BCL-XL inhibitor APG-1252-mediated cleavage of GSDME enhances the antitumor efficacy of HER2-targeted therapy in HER2-positive gastric cancer: 《Acta Pharmacologica Sinica》2025年第4期1082-1096,共15页Qiu-yun Luo Jing Yang Tian Di Zeng-fei Xia Lin Zhang Wen-tao Pan Shan Shi Li-qiong Yang Jian Sun Miao-zhen Qiu Da-jun Yang; supported by the National Natural Science Foundation of China(NSFC:82172748 and 82073377);the Guangdong Basic and Applied Basic Research Foundation(2024B1515020120 and 2023A1515110567);the Medical Scientific Research Foundation of Guangdong Province(A2024171).; HER2-positive gastric cancer has a poor prognosis,with a high incidence of drug resistance and a lack of effective treatments for drug-resistant patients.The exploration of the mechanism of resistance to HER2-targeted...; 关键词：HER2-positive gastric cancer GSDME PYROPTOSIS APG-1252

Enhanced conversion of lignin into mono-cycloalkanes via C–C bonds cleavage over multifunctional Pt-Nb/MOR catalyst: 《Chinese Journal of Catalysis》2025年第4期285-296,共12页Zhiruo Guo Xiaohui Liu Yong Guo Yanqin Wang; 国家重点研发计划(2022YFA1504903);国家自然科学基金(22172048).; The efficient conversion of lignin into mono-cycloalkanes via both C–O and C–C bonds cleavage are attractive,but challenging due to the high C–C bond dissociation energy.Previous studies have demonstrated that NbO_...; 关键词：LIGNIN Mono-cycloalkanes C-C bond cleavage Pt-Nb/MOR catalyst

New techniques and strategies in drug discovery(2020–2024 update): 《Chinese Chemical Letters》2025年第3期104-112,共9页Qijie Gong Jian Song Yihui Song Kai Tang Panpan Yang Xiao Wang Min Zhao Liang Ouyang Li Rao Bin Yu Peng Zhan Saiyang Zhang Xiaojin Zhang; supported by grants from the National Natural Science Foundation of China(No.82273770);the Foundation for Innovative Research Groups of the National Natural Science Foundation of Sichuan Province(No.24NSFTD0051).; In the realm of drug discovery,recent advancements have paved the way for innovative approaches and methodologies.This comprehensive review encapsulates six distinct yet interrelated mini-reviews,each shedding light o...; 关键词：Drug discovery Covalent inhibitors Computational drug design Protein scaffolding Pro-PROTACs Programmed cell death C-C cleavage

Nucleophilic cleavage of C-F bonds by Brønsted base for rapid synthesis of fluorophosphate materials: 《National Science Review》2025年第3期285-296,共12页Qingfeng Fu Zihao Chang Peng Gao Wang Zhou Hongliang Dong Peifeng Huang Aiping Hu Changling Fan Peitao Xiao Yufang Chen Jilei Liu; supported by the National Key Research and Development Program of China(2022YFE0206300);the National Natural Science Foundation of China(U21A2081,22075074,22209047 and 51972104);the Macao Science and Technology Development Fund(0013/2021/AMJ);the Foundation of Yuelushan Center for Industrial Innovation(2023YCII0119).; Fluorochemicals are a rapidly expanding class of materials used in a variety of fields including pharmaceuticals,metallurgy,agrochemicals,refrigerants,and in particular,alkali metal ion batteries.However,achieving one...; 关键词：fluorophosphate compounds C-F bond polytetrafluoroethylene potassium-ion battery

Synergistic sites over the Zn_(x)ZrO catalyst for targeted cleavage of the C-H bonds of ethane in tandem with CO_(2)activation: 《Chinese Journal of Catalysis》2025年第3期272-284,共13页Wenjun Qiang Duohua Liao Maolin Wang Lingzhen Zeng Weiqi Li Xuedong Ma Liang Yang Shuang Li Ding Ma; 国家自然科学基金(21878244,22472130);太原理工大学煤炭清洁高效利用国家重点实验室基金(MJNYSKL202407).; The CO_(2)-assisted oxidative dehydrogenation of ethane(CO_(2)-ODHE)provides a promising way to produce ethylene and utilize CO_(2).Simultaneous upgrading of ethane into the high value-added chemical products and the ...; 关键词：Zn-O-Zr site Oxygen vacancies CO_(2) Ethylene space-time yield Tandem reaction

Transition-metal-free isofunctional reaction of α,β-unsaturated ketones/nitriles: 《Science China Chemistry》2025年第2期499-504,共6页Runyou Ye Jialin Ming Qinyue Tao Tian-Yu Gao Jian-Heng Ye Da-Gang Yu Xiangge Zhou; supported by the National Natural Science Foundation of China(22071159);Sichuan Science and Technology Program(2018JY560)。; Isofunctional reactions involving the cleavage of carbon-carbon double bonds(C=C)hold an important position in organic synthesis,as they allow for the restructuring of alkene carbon chains and enable the exchange of f...; 关键词：isofunctional reaction transition-metal-free C=C cleavage base-promoted Michael addition

An azo bond primary cleavage and C–C bond secondary cleavage-based polymeric β-lapachone prodrug for selective anti-cancer therapy: 《Science China Materials》2025年第2期640-651,共12页Weidong Zhao Mengfei Zheng Hongyu Chu Jingxuan Zhang Kun Wang Chenguang Yang Na Shen Zhaohui Tang; financially supported by the Ministry of Science and Technology of the People’s Republic of China (2022YFE0110200);the National Natural Science Foundation of China (52025035, 52273157, and 52073279);the Department of Science and Technology of Jilin Province (20240305041YY and 20230508102RC);the Youth Innovation Promotion Association of the Chinese Academy of Sciences (2022224)。; β-Lapachone (β-Lap) is a promising orthonaphthoquinone drug for cancer treatment and has been inclinical trials. Its application is constrained by the low aqueoussolubility, and severe side effects. Even prodrug des...; 关键词：β-lapachone NQO1 C-C bond cleavage polymeric nanoprodrug azo linkage

Electrocatalytic cleavage of a lignin β-O-4 model compound and coupling with nitrogen-containing aromatics using Prussian blue analogue-derived nickel–cobalt spinel: 《Journal of Energy Chemistry》2025年第1期628-636,共9页Yi Qi Xueying Chen Bowen Liu Xuliang Lin Xueqing Qiu Yanlin Qin; National Natural Science Foundation of China (U23A6005 and 22078069);Project funded by China Postdoctoral Science Foundation (GZB20230172 and 2023M740748)。; Electrochemical conversion of lignin for the production of high-value heterocyclic aromatic compounds has great potential.We demonstrate the targeted synthesis and cation modulation of NiCo_(2)O_(4)spinel nanoboxes,sy...; 关键词：SPINEL Biomass valorization Electrocatalysis Lignin oxidation Coupling

Co nanoparticles confined in mesopores of MFI zeolite for selective syngas conversion to heavy liquid hydrocarbon fuels: 《Chinese Journal of Catalysis》2025年第1期246-258,共13页Neng Gong Quanzheng Deng Yujiao Wang Zitao Wang Lu Han Peng Wu Shun'ai Che; 国家自然科学基金(21931008);国家重点研发计划(2021YFA1200301,2021YFA1501401).; Designing Fischer-Tropsch synthesis(FTS)catalysts to selectively produce liquid hydrocarbon fuels is a crucial challenge.Herein,we selectively introduced Co nanoparticles(NPs)into the micropores and mesopores of an or...; 关键词：Fischer-Tropsch synthesis Heavy liquid hydrocarbon fuel Co nanoparticle Ordered mesoporous MFI zeolite C-C cleavage

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