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CNS: 作品数：582被引量：1778H指数：18; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：缪鸿石田金文刘劲王庆松朱京慈更多>>; 相关机构：萨奇治疗股份有限公司第三军医大学弗·哈夫曼-拉罗切有限公司夏尔人类遗传性治疗公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>

Metabolic checkpoints in neurodegenerative T helper 17（TH17） and neuroregenerative regulatory T(Treg) cells as new therapeutic targets for multiple sclerosis被引量：2: 《Neural Regeneration Research》2020年第2期267-269,共3页Hongxing Shen James A. Bonner Lewis Zhichang Shi; funded by the V Foundation Scholar Award(V2018-023);ACS-IRG(91-022-19);R21(1R21CA230475-01A1)to LZS; The central nervous system (CNS) is an immune-privileged site with tightly-regulated immune responses, a concept proposed by Nobel Laureate Sir Peter Medawar in 1960. Under physiological conditions, only a few T lymph...; 关键词：METABOLIC CHECKPOINTS multiple SCLEROSIS CNS

The role of muscle LIM protein in the nervous system: 《Neural Regeneration Research》2019年第11期1907-1908,共2页Daniel Terheyden-Keighley Dietmar Fischer; supported by the German Research Foundation(FI 867/12,to DF); Unlike the peripheral nervous system (PNS), the central nervous system (CNS) has a low intrinsic regenerative capacity and has mechanisms that actively suppress axon regrowth, for example, glial scarring and myelin in...; 关键词：LIM nervous SYSTEM PERIPHERAL nervous system(PNS) CENTRAL nervous system(CNS)

Emerging roles for insulin-like growth factor binding protein like protein 1: 《Neural Regeneration Research》2019年第2期258-259,共2页Yingqian Li Eric Zhao Dong Feng Chen; supported by grants from the National Institutes of Health(EY025913 and EY025259);the Massachusetts Lion’s Foundation(to DFC); Insulin-like growth factors (IGFs) mediate diverse cellular processesin various tissues, including the central nervous system (CNS)and thus require robust and delicate regulatory mechanisms. Itis now known that IGF si...; 关键词：ET al IGFBPL CNS

Semaphorin 3A: from growth cone repellent to promoter of neuronal regeneration被引量：3: 《Neural Regeneration Research》2018年第5期795-796,共2页Bor Luen Tang; Highlight Semaphorin 3A is a classically known axonal guidance cue that mediates axonal growth cone repulsion and collapse.Recent works,however,suggest that it may have the apparently diametrically opposite activity o...; 关键词：from growth cone repellent to promoter of neuronal regeneration CNS Semaphorin 3A

Regulation of neuroinflammatory properties of glial cells by T cell effector molecules被引量：1: 《Neural Regeneration Research》2018年第2期234-236,共3页chittappen k.prajeeth jochen huehn martin stangel; supported by the Helmholtz-Gemeinschaft,“Zukunft-sthema”Immunology and inflammation”(ZT-0027);supported by the Pertermax-Müller-Stiftung and the Niedersachsen Research Network on Neuroinfectiology(N-RENNT)of the Ministry of Science and Culture of Lower Saxony; Multiple sclerosis （MS） is a chronic inflammatory and neurodegenerative disorder that is thought to be mediated by autoreactive T lymphocytes that find their way into the central nervous system （CNS）. The patholog...; 关键词：Regulation of neuroinflammatory properties of glial cells by T cell effector molecules TH CNS

Collagen 1 signaling at the central nervous system injury site and astrogliosis: 《Neural Regeneration Research》2017年第10期1600-1601,共2页Sin Hui Neo Bor Luen Tang; supported by the NUS Graduate School for Integrative Sciences and Engineering; Central nervous system （CNS） injuries are often devastating as func- tional recovery via axonal regrowth over the lesion site is very minimal.; 关键词：ECM CNS

Genetically modifying transcription factors to promote CNS axon regeneration: 《Neural Regeneration Research》2017年第5期737-738,共2页Saloni T.Mehta John L.Bixby Vance P.Lemmon; supported by NIH HD057632 to VPL and JLB.VPL holds the Walter G.Ross Distinguished Chair in Developmental Neuroscience; Following injury to the central nervous system（CNS）,severed axons fail to regenerate and re-form functional connections.Accordingly,CNS neurons appear to lack the intrinsic ability to modify their gene expression pa...; 关键词：CNS gene JUN VP

The exciting potential of nanotherapy in brain-tumor targeted drug delivery approaches: 《Neural Regeneration Research》2017年第2期197-200,共4页Vivek Agrahari; Delivering therapeutics to the central nervous system（CNS） and brain-tumor has been a major challenge. The current standard treatment approaches for the brain-tumor comprise of surgical resection followed by immunot...; 关键词：brain-tumor glioma CNS blood-brain barrier drug transport nanoformulation nanocarrier cell-mediated drug delivery

Intracellular compartmentation of cAMP promotes neuroprotection and regeneration of CNS neurons被引量：1: 《Neural Regeneration Research》2017年第2期201-202,共2页Evan G.Cameron Michael S.Kapiloff; supported by National Eye Institute grants R01 EY022129 and EY026766 to MSK and F32 EY025915 to EGC; In the central nervous system（CNS）,cyclic adenosine monophosphate（cAMP）plays a critical role in numerous,often concurrent,neuronal functions including survival,growth,differentiation and synaptogenesis.; 关键词：AMP PDES CNS

Tauroursodeoxycholic acid:more than just a neuroprotective bile conjugate: 《Neural Regeneration Research》2017年第1期62-63,共2页Lorenzo Romero-Ramírez Manuel Nieto-Sampedro Natalia Yanguas-Casás; supported by grants from the Spanish Ministry of Science and Innovation(SAF2009-11257);the Spanish Ministry of Economy and Competitivity(SAF2012-40126);grants PI2008/19 and PI2009/51 from the FISCAM-Castilla-La Mancha Community; Neurological diseases and the neuroinflammatory response：Neurological diseases are usually accompanied by dramatic changes in the tissue homeostasis,inducing a neuroinflammatory environment that leads to the progress...; 关键词：Tauroursodeoxycholic acid more than just a neuroprotective bile conjugate TGF CNS

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