supported by the National Key Technologies R&D Program[grant number 2017YFC0110904];the Beijing Natural Science Foundation[grant number L222149];the Beijing Municipal Administration of Hospitals’Youth Programme[grant number QML20230122];the Beijing Municipal Administration of Hospitals Incubating Program[grant number PX2022002].
Background:Stage II colon cancer has varying risks for metastasis,and treatment strategies depend on molecular and clinicopathological features.While tumor-sidedness is a well-accepted prognostic factor for stage III/...
supported by National Key Clinical Discipline,the Fundamental Research Funds for the young teacher training program of Sun Yat-sen University[grant number 18ykpy02];the“5010 Clinical Research Program”of Sun Yat-sen University[grant number 2010012];the Natural Science Foundation of Guangdong Province,China[grant number 2020A1515010428];the Medical Science Research Grant from the Health Department of Guangdong Province[grant number A2018007].
Background Prognosis varies among patients within the same colon adenocarcinoma(COAD)stage,indicating the need for reliable molecular markers to enable individualized treatment.This study aimed to investigate gene sig...
supported by grants from Shenzhen Longhua District Science and Technology Innovation Breau[201801 to K.W.L.];Shenzhen Municipal Science and Technology program of China[JCYJ20160425100840929 to K.W.L.];the Natural Science Foundation of Guangdong province[2019A1515011009 to H.C.G.].
Background Green tea is a popular beverage worldwide and epigallocatechin-3-gallate(EGCG)is the most bioactive polyphenol in green tea.Our study aims to investigate the anti-proliferation and anti-migration effects of...
supported by the Beijing Municipal Science&Technology Commission[No.Z161100000116090];the National Key Research and Development Program of the Ministry of Science and Technology of China[No.2016YFC0905303];the CAMS Innovation Fund for Medical Sciences(CIFMS)[No.2016-I2M-1–001];the Beijing Science and Technology Program[No.D17110002617004].
Background:Both pre-operative anemia and perioperative(intra-and/or post-operative)blood transfusion have been reported to increase post-operative complications in patients with colon cancer undergoing colectomy.Howev...
This work was supported by National Key Clinical Discipline,the Fundamental Research Funds for the young teacher training program of Sun Yat-sen University[grant number 18ykpy02];Medical Scientific Research Foundation of Guangdong Province of China[grant number A2016198];‘5010 Clinical Research Programme’of Sun Yat-sen University[grant number 2010012].
Background:The tumor immune microenvironment is one of the most important prognostic factors in liver metastasis from colorectal cancer.Low-dose cyclophosphamide(CTX)is widely believed to be involved in the modulation...
Colorectal cancer remains one of the most common cancers worldwide and,despite improvements in treatment options for late-stage metastatic cancer,there are still questions surrounding how best to treat early-stage dis...
Throughout history,surgeons have been on a quest to refine the surgical treatment options for their patients and to minimize operative trauma.During the last three decades,there have been tremendous advances in the fi...
An oncological surgical resection is the mainstay of treatment for potentially curable colon cancer.At the time of surgery,a large fraction of patients do harbour—although not visibly—minimal residual disease at the...
This work was supported by the following grants:National Natural Science Foundation of China(No.81071164,No.81271584);Zhejiang Provincial Natural Science Foundation of China(No.Y2110782);Public Technology for Applied Research Program Foundation from the Science and Technology Bureau of Zhejiang Province(No.2013C31002);Key Program Foundation from the Health Bureau of Zhejiang Province(No.2013ZDA020);the General Program Foundation from the Hangzhou City Health Bureau(No.2013A27).
Objective:to evaluate the therapeutic effect of targeted endostatin-loaded microbubbles,combined with improved,focused,directional ultrasound radiation for inhibition of subcutaneous translocation in situ colon tumor ...
The standardization of colon cancer surgery has been an area of intense interest.The recent establishment of the complete mesocolic excision(CME)technique has defined the operative approach for colon cancer surgeries ...