supported by the National Natural Science Foundation of China(No.22177060);the Young Scholars Program of Shandong University(No.2018WLJH41);the Open Projects Fund of Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology,Shandong University(No.2021CCG06);the Central Government Guide Local Science and Technology Development Funds(No.YDZX20203700002579)。
A family of the 3,6-branched Fuziα-glucans including the pentasaccharide repeating unit as well as its di-and trimers were efficiently achieved via a one-pot and convergent glycosylation strategy.All the protectedα-...
support from the National Natural Science Foundation of China(Nos.21901215,21672030);the Fundamental Research Funds for the Central Universities(No.2682021CG020).
Taxol is one of the most famous diterpenoid natural products used in clinical cancer therapy.Taxol and its analogues are popular synthetic targets and have attracted worldwide attention over the past decades.Tremendou...
Ministry of Science & Technology (No.2013CB836900);National Natural Science Foundation of China (Nos.21290180,21172235 and 21222202);China Postdoctoral Science Foundation (No.2014M561537,M.Y.)
Chlorospermines A and B are biologically interesting acridone natural products and recently isolated from Glycosmis chlorosperma.We report here a convergent approach to construct the tetracyclic core of the natural pr...
support by the National Natural Science Foundation of China(No.21307053);China Postdoctoral Science Foundation Funded Project(No.2013M541911);Promotive Research Fund for Excellent Young and Middle-Aged Scientists of Shandong Province(No.BS2013CL044);Natural Science Foundation of Ludong University(No.LY2011004)
A series of novel ester-capped carbosilane dendrimers(G0-COOCH3–G2-COOCH3) were designed and successfully synthesized via a hybrid divergent–convergent method through a facile hydrosilylation reaction. The structu...
support of National Natural Science Foundation of China(No.20472055).
This paper describes the facile synthesis and characterization of novel dendrimers bearing 9 and 12 CCK peptide fragments on the surface by a convergent method. The structures of dendrimers are characterized by NMR an...
The authors gratefully acknowledge financial support from the National Natural Science Foundation of China(No.39370809);National New Drug Foundation(No.92-08-N).
AF-5 was synthesized through a convergent method. The key step was the Robinson annulation using a key intermediate pentyl vinyl ketone.
The synthesis of epoxy aldehyde 4, a cyclization precursor for the total synthesis of 14-deoxycrassin and pseudoplexaurol, starting from geraniol in a convergent and stereoselective manner, is described.
Starting form geanial a new Synthetic route for compound 6, (E,E,E)-3,7-13-trimethy1-6-(i-propenyl)-7,14-dihydydroxy1-2,8,12-tetradecatrien-1-methylal,a key intermediate in the synthesis of diterpene epi-mayol is desc...
A cembrenene precursor,4,10-dimethyl-7-isopropenyl-14-oxo-3Z,5E,10Epentadecatrienal,was prepared in a convergent and stereoselective manner starting from geranylacetone via six steps employing allylic chlorination,Wit...
A precursor of sarcophytol-Q, (11 S) -3, 7, 11, 15-tetramethyl-11-hydroxy-14-oxo-3E, 7E, 12E-hexadecatrienal, was synthesized by a convergent and stereoselective manner from geraniol via nine steps employing asymmetri...