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作品数:471被引量:853H指数:13
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相关领域:医药卫生更多>>
相关作者:潘铁成李意民周涛谷勇霞周忠宁更多>>
相关机构:中国科学院上海交通大学中国科学院大学济南大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study被引量:5
《Chinese Medical Journal》2019年第3期269-274,共6页Zhe Zhang Dan-Hua Zhao Xu-Tong Zhao Xiao Zhang Hui Xiong Xin-Hua Bao Yun Yuan Zhao-Xia Wang 
the grants from the Ministry of Science and Technology of China (No.2011ZX09307- 001-07);the National Natural Science Foundation of China (No.81571219);the Beijing Municipal Science and Technology Commission (No.Z151100003915126).
Background:Studies on the relationship between antiepileptic drug (AED) administration and clinical outcomes in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) remain s...
关键词:Syndrome Seizures EPILEPSY ANTICONVULSANTS LEVETIRACETAM Survival analysis 
Effect of Shensong Yangxin on the Progression of Paroxysmal Atrial Fibrillation is Correlated with Regulation of Autonomic Nerve Activity被引量:17
《Chinese Medical Journal》2017年第2期171-178,共8页Hong-Yi Zhao Shu-Di Zhang Kai Zhang Xi Wang Qing-Yan Zhao Shu-Juan Zhang Zi-Xuan Dai Yong-Sheng Qian You-Jing Zhang Hao-Tian Wei Yan-Hong Tang Cong-Xin Huang 
Background: Shensong Yangxin (SSYX), a traditional Chinese herbal medicine, has long been used clinically to treat arrhythmias in China. However, the mechanism of SSYX on atrial fibrillation (AF) is unknown. In t...
关键词:Atrial Fibrillation Autonomic Nerve Cholinergic Anti-inflammatory Pathway Inflammatory Cytokines ShensongYangxin 
Elimination Rate of Serum Lactate is Correlated with Amyotrophic Lateral Sclerosis Progression被引量:5
《Chinese Medical Journal》2016年第1期28-32,共5页Yuan-Jin Zhang Dong-Sheng Fan 
Background: Mitochondrial dysfunction plays an important role in the pathogenesis of amyotrophic lateral sclerosis (ALS). We aimed to demonstrate mitochondrial dysfunction in ALS using a lactate stress test and to ...
关键词:Advanced Phase Amyotrophic Lateral Sclerosis Early Phase Elimination Rate of Serum Lactate 
Circulating ghrelin was negatively correlated with pulmonary arterial pressure in atrial septal defect patients
《Chinese Medical Journal》2013年第20期3936-3939,共4页Li Zhao-feng Zhou Da-xin Pan Wen-zhi Zhang Lei Ge Jun-bo 
Background Ghrelin was found to attenuate the magnitude of pulmonary arterial hypertension and pulmonary vascular remodeling in rats. The objective of this study was to explore the fasting plasma ghrelin level and the...
关键词:GHRELIN OBESTATIN atrial septal defect  pulmonary arterial hypertension 
Chronic obstructive pulmonary disease assessment test score correlated with dyspnea score in a large sample of Chinese patients被引量:5
《Chinese Medical Journal》2013年第1期11-15,共5页ZHOU Qing-tao MEI Jing-jing HE Bei HUANG Shao-guang SHI Yi WEN Fu-qiang ZHAO Ming-wu 
Background The chronic obstructive pulmonary disease assessment test (CAT) is an easy to use health-related quality of life questionnaire, the modified Medical Research Council (mMRC) dyspnea scale is a classic dy...
关键词:chronic obstructive pulmonary disease DYSPNEA quality of life QUESTIONNAIRE 
Urinary albumin excretion rate is correlated with severity of coronary artery disease in elderly type 2 diabetic patients被引量:4
《Chinese Medical Journal》2012年第23期4181-4184,共4页GUO Li-xin MA Jing CHENG Yang ZHANG Li-na LI Ming 
The study was supported by a grant from the Beijing Municipal Natural Science Foundation of China (No. 7062059).
Background Coronary heart disease is the main complication of type 2 diabetes mellitus; its incidence is closely related to microalbuminuria. The aim of this study was to investigate the correlation between the urinar...
关键词:type 2 diabetes mellitus coronary heart disease urinary albumin excretion rate Gensini score 
Chemerin and apelin are positively correlated with inflammation in obese type 2 diabetic patients被引量:28
《Chinese Medical Journal》2012年第19期3440-3444,共5页YU Shan ZHANG Ying LI Mei-zhen XU Hua WANG Qian SONG Jun LIN Peng ZHANG Li LIU Qian HUANG Qing-xian WANG Kun HOU Wei-kai 
Background As two novel adipocytokines, chemerin and apelin play a key role in the pathological process of insulin resistance (IR), glucose metabolism and obesity, researchers have found that the levels of chemerin ...
关键词:type 2 diabetes mellitus OBESITY insulin resistance CHEMERIN APELIN 
Toll-like receptor 9 is correlated to disease activity in Chinese systemic lupus erythematosus population被引量:3
《Chinese Medical Journal》2012年第16期2873-2877,共5页MU Rong SUN Xiao-yun Lik Thai Lim XU Chuan-hui DAI Chen-xian SU Yin JIA Ru-lin LI Zhan-guo 
Methods mRNA level of TLR9 and interferon (IFN) regulatory factor 5 (IRF5) in peripheral blood mononuclear cells (PBMCs) were determined by real-time polymerase chain reaction (PCR). IFN-a expression was measu...
关键词:Toll-like receptor 9  interferon regulatory factor 5  interferon alpha  systemic lupus erythematosus 
Tumor-infiltrating regulatory T cells are positively correlated with angiogenic status in renal cell carcinoma被引量:3
《Chinese Medical Journal》2012年第12期2120-2125,共6页NING Hao SHAO Qian-qian DING Ke-jia GAO De-xuan LU Qing-le CAO Qing-wei NIU Zhi-hong FU Qiang ZHANG Chun-huan QU Xun LU Jia-ju 
This study was supported by the grants from the National Natural Science Foundation of China (No. 81072406) and the Natural Science Foundation of Shandong Province (No. Y2006C71 and No. ZR2011HQ027).
Background Immune cells within a tumor microenvironment have shown modulatory effects on tumor angiogenic activity. Renal cell carcinoma (RCC) is a hypervascular tumor that reportedly increases the frequency of regu...
关键词:regulatory T cells renal cell carcinoma vascular endothelial growth factor ANGIOGENESIS microvessel density 
Overexpression of interleukin-17 in tumor-associated macrophages is correlated with the differentiation and angiogenesis of laryngeal squamous cell carcinoma被引量:14
《Chinese Medical Journal》2012年第9期1603-1607,共5页MENG Cui-da ZHU Dong-dong JIANG Xiao-dan LI Lin SHA Ji-chao DONG Zhen KONG Hong 
Background Interleukin-l7 (IL-17), which exerts strong pro-inflammatory effects, has emerged as an important mediator in inflammation-associated cancer. The aim of this study was to clarify the relationship between...
关键词:laryngeal squamous cell carcinoma interleukin 17 tumor-associated macrophages inflammation microvessel density 
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