LEVETIRACETAM

作品数:29被引量:35H指数:4
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相关领域:医药卫生更多>>
相关作者:冯建华王建怡廖钊何凤娟张烨更多>>
相关机构:浙江大学贵州省人民医院遵义医学院台湾大学更多>>
相关期刊:《World Journal of Clinical Cases》《Asian Journal of Pharmaceutical Sciences》《World Journal of Clinical Pediatrics》《Journal of Hainan Medical University》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Development of SV2A Ligands for Epilepsy Treatment:A Review of Levetiracetam,Brivaracetam,and Padsevonil被引量:1
《Neuroscience Bulletin》2024年第5期594-608,共15页Peng-Peng Wu Bi-Rong Cao Fu-Yun Tian Zhao-Bing Gao 
supported by funding from the High-level New R&D Institute(2019B090904008);the High-level Innovative Research Institute(2021B0909050003)of the Department of Science and Technology of Guangdong Province;National Science and Technology Innovation 2030 Major Program(2021ZD0200900);Shanghai Municipal Science and Technology Major Project(2018SHZDZX05);Zhongshan Municipal Bureau of Science and Technology(CXTD2022013);the National Science Fund for Distinguished Young Scholars(81825021);the funding from Zhongshan Municipal Bureau of Science and Technology(210724194041939).
Epilepsy is a common neurological disorder that is primarily treated with antiseizure medications(ASMs).Although dozens of ASMs are available in the clinic,approximately 30%of epileptic patients have medically refract...
关键词:LEVETIRACETAM EPILEPSY Antiseizure medications Synaptic vesicle protein 2A BRIVARACETAM Padsevonil 
Effect of levetiracetam and valproate on late‑onset post‑traumatic seizures
《Acta Epileptologica》2023年第2期86-89,共4页Yanli Wang Yiqi Wang Huifang Wang Xiaoping Du Jie Miao James X.Tao Meizhen Sun 
funded by the Scientific Research Fund of China Association Against Epilepsy(No 2012002).
Background To compare the preventive effects of levetiracetam and valproate on late-onset post-traumatic seizures in patients with traumatic brain injury(TBI).Methods A total of 95 patients with TBI were recruited fro...
关键词:LEVETIRACETAM Valproate Post-traumatic seizure 
Amiodarone-induced muscle tremor in an elderly patient:A case report被引量:1
《World Journal of Clinical Cases》2022年第34期12726-12733,共8页Xiao-Yong Zhu Xin-Hu Tang Hua Yu 
BACKGROUND Amiodarone is a Class III antiarrhythmic drug,which has been adopted for the treatment of atrial fibrillation and ventricular arrhythmia.However,the use of amiodarone can cause lower limb muscle tremors,whi...
关键词:Adverse reaction ARRHYTHMIA Muscle disease AMIODARONE LEVETIRACETAM Case report 
Pneumonia and seizures due to hypereosinophilic syndrome—organ damage and eosinophilia without synchronisation:A case report被引量:2
《World Journal of Clinical Cases》2022年第18期6325-6332,共8页Tetsuro Ishida Tomonori Murayama Seiju Kobayashi 
BACKGROUND Hypereosinophilic syndrome(HES)is a condition characterized by increased eosinophil proliferation in the bone marrow,as well as tissue eosinophilia,often causing organ damage.The cause of the disease is unk...
关键词:Case report Hypereosinophilic syndrome PNEUMONIA Seizures PREDNISOLONE LEVETIRACETAM 
Acute Kidney Injury with Levetiracetam in Patient with Epilepsy: A Case Report
《Case Reports in Clinical Medicine》2022年第3期48-54,共7页Khalid Al-Quliti Rakan Maher Alhujeily 
Epilepsy is a common neurological disorder in neurology clinic. Levetiracetam is considered as one of common antiepileptic drugs used to manage epilepsy with good efficacy and tolerability profile. It is renally excre...
关键词:Acute Kidney Injury EPILEPSY LEVETIRACETAM 
Innovative color jet 3D printing of levetiracetam personalized paediatric preparations被引量:2
《Asian Journal of Pharmaceutical Sciences》2021年第3期374-386,共13页Zengming Wang Xiaolu Han Ruxin Chen Jingru Li Jing Gao Hui Zhang Nan Liu Xiang Gao Aiping Zheng 
This work was supported by the National Natural Science Foundation of China(No.82073793);the National Major Science and Technology Projects of China(No.2018ZX09721003-007/No.2018ZX09J18107).
3D printing is a promising technology used in the fabrication of complex oral dosage delivery pharmaceuticals.This study first reports an innovative color jet 3D printing(CJ-3DP)technology to produce colorful cartoon ...
关键词:Color jet 3D printing Paediatric preparations Personalized administration Medicine dosage model Immediate release 
Effects of sodium valproate combined with levetiracetam in treatment of children epilepsy and its influences on serum S-100βand high mobility group box-1
《Discussion of Clinical Cases》2020年第1期12-18,共7页Huimin Li Jinli Hao Hua Chen Yong Meng 
Objective:To explore the effects of sodium valproate combined with levetiracetam in the treatment of children epilepsy,and its influences on serum S-100βand high mobility group box-1(HMGB-1)in children with epilepsy....
关键词:EPILEPSY Sodium valproate LEVETIRACETAM S-100 HMGB-1 protein Tumor necrosis factor- HAEMATOCRIT CHILDREN 
Beneficiality of combined levetiracetam, clonazepam for myoclonus in MERRF requires further confirmation被引量:3
《Chinese Medical Journal》2019年第5期622-623,共2页Josef Finsterer 
To the Editor: With interest, we read the article by Su et al[1] about the antiepileptic drug (AED) treatment of 17 patients with genetically confirmed myoclonic epilepsy with ragged-red fibers (MERRF) syndrome. It wa...
关键词:COMBINED LEVETIRACETAM MYOCLONUS MERRF 
Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study被引量:5
《Chinese Medical Journal》2019年第3期269-274,共6页Zhe Zhang Dan-Hua Zhao Xu-Tong Zhao Xiao Zhang Hui Xiong Xin-Hua Bao Yun Yuan Zhao-Xia Wang 
the grants from the Ministry of Science and Technology of China (No.2011ZX09307- 001-07);the National Natural Science Foundation of China (No.81571219);the Beijing Municipal Science and Technology Commission (No.Z151100003915126).
Background:Studies on the relationship between antiepileptic drug (AED) administration and clinical outcomes in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) remain s...
关键词:Syndrome Seizures EPILEPSY ANTICONVULSANTS LEVETIRACETAM Survival analysis 
Pharmacokinetics, safety and bioequivalence of intravenous and oral formulations of the antiepileptic drug levetiracetam in healthy Chinese volunteers被引量:2
《Journal of Chinese Pharmaceutical Sciences》2018年第11期777-786,共10页Lanlan Hu Juan Zhou Huan Zou Yue Zhang Jianlin Tang 
The intravenous formulation of levetiracetam (LEV)has been available in clinical practice worldwide for several years,but not in China.In the present study,we aimed to evaluate the bioequivalence of intravenous and or...
关键词:LEVETIRACETAM EPILEPSY Intravenous formulation BIOEQUIVALENCE Safety and tolerability 
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