supported by the National Basic Research Program of China(2010CB912403);the National Natural Science Foundation of China(31370730 and 31070144)
Hand, foot and mouth disease(HFMD) is a significant health concern in the Asia–Pacific regions for infants and young children in recent years. However, no vaccines or therapeutics are available at present. The causat...
A series of 1,2,4-triazole derivatives were synthesized, and their abilities to inhibit the in vitro replication of Coxsackie B3/B6 were evaluated. Among the 1,2,4-triazole derivatives, compound 3 g displayed potent a...
supported by the National Basic Research Program of China (Grant No. 2011CB504903);the National Natural Science Foundation of China (Grant No. 81171573);the Important National Science & Technology Specific Projects (Grant No. 2009ZX10004-308);the General Program of Applied Basic Research Programs Commission, Foundation of Yunnan Province (Grant No. 2011FB116)
Coxsackie A virus is one of the major pathogens associated with hand, foot and mouth disease (HFMD). The etiological characteristics of Coxsackie A virus type 16 (CA16) are thought to correlate with the pathological p...
OBJECTIVE To explore the relationship between CAR and the development of human lung cancer, as well as to provide the basis for the clinical treatment of lung cancer using an adenovirus vector-based gene therapy. METH...
This work was supported in part by the National High Tech Development Project of China, the 863 Program (No. 2007AA02Z329), the National Natural Science Foundation of China (No. 30370798, 30571034, and 30570424) and the Key Project of Heilongjiang Province (No. GB07C32402)
Background Although clinical treatment for heart failure and sudden death has been improved over the last few decades, the morbidity and mortality of dilated cardiomyopathy (DCM) have increased. So a better understa...
Supported by the Funds from Medical Sciences/University of Tehran and Iranian Ministry of Health and Medical Education
AIM: To investigate the expression of coxsackievirus and adenovirus receptor (CAR) and adenovirus-mediated reporter gene transfer in five human colon cancer cell lines.METHODS: Expression of CAR-specific mRNA and ...