COXSACKIE

作品数:47被引量:134H指数:6
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相关领域:医药卫生更多>>
相关作者:杨英珍陈灏珠钱素娟于维汉金佩英更多>>
相关机构:哈尔滨医科大学上海医科大学附属中山医院中国科学院上海生命科学研究院复旦大学更多>>
相关期刊:《中国公共卫生学报》《Science Bulletin》《International Journal of Organic Chemistry》《中华国际医学杂志》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划卫生部科技专项基金陕西省科学技术研究发展计划项目更多>>
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北京某幼儿园一起集中发热疫情的病原学分析被引量:1
《国际病毒学杂志》2016年第4期233-235,257,共4页杜轶威 李洁 曲梅 杨扬 霍达 梁志超 潘阳 王全意 
北京市高层次卫生技术人才培养计划(2013-3-099)
目的 对北京市某幼儿园集中发热疫情中的病例进行病因研究,分析其病原学特征.方法 采集该幼儿园13位发热患者的咽拭子标本,利用RT-PCR扩增肠道病毒VP1区基因序列,测序分析病原分子特征.结果 8名病例为肠道病毒核酸通用阳性,测序分析发...
关键词:发热 肠道病毒 CoxA4型 COXSACKIE virus A4 
Achievements, challenges and prospects for the development of broadly protective multivalent vaccines and therapeutic antibodies against hand, foot and mouth disease被引量:3
《Science Bulletin》2015年第15期1305-1315,共11页Ke Lyu Rong Chen 
supported by the National Basic Research Program of China(2010CB912403);the National Natural Science Foundation of China(31370730 and 31070144)
Hand, foot and mouth disease(HFMD) is a significant health concern in the Asia–Pacific regions for infants and young children in recent years. However, no vaccines or therapeutics are available at present. The causat...
关键词:HAND foot and mouth disease (HFMD) Human enterovirus 71 (EV71) Coxsackievirus A 16(CVAI6) - Vaccine Neutralizing antibodies 
肠道病毒EV71感染后标志物变化特点分析被引量:5
《中华疾病控制杂志》2014年第1期40-43,共4页余鹏博 马超锋 关路媛 陈海龙 郑媛 魏菁 许晶 李慎 徐纪茹 王敬军 邓慧玲 
国家科技重大专项(2013ZX10004202);陕西省科学技术研究发展项目(2011K12-82);西安市卫生局科技项目(J2011028);西安市科学技术局医疗卫生研究项目(SF1208)
目的 观察分析手足口病常见病原肠道病毒71型(enterovirus71,EV71)早期检测效果及其随病程进展感染标志物变化特点.方法 整群抽样手足口病住院病例249人及健康对照50人,调查信息,跟踪采样,采集肛拭子和血清标本,分别检测EV71、柯萨奇...
关键词:手足口病 肠道病毒A型  柯萨奇A16 COXSACKIE 16 
Design, Synthesis and Inhibitory Properties against Coxsackie B3/B6 of Some Novel Triazole Derivatives
《International Journal of Organic Chemistry》2013年第1期41-46,共6页Dongping Shao Yanbing Yang Fei Xue Xianjin Luo Reyila Wubulikasimu Yuhuan Li Rongmei Gao Weidong Ye 
A series of 1,2,4-triazole derivatives were synthesized, and their abilities to inhibit the in vitro replication of Coxsackie B3/B6 were evaluated. Among the 1,2,4-triazole derivatives, compound 3 g displayed potent a...
关键词:1 2 4-Triazole Anti-Enterovirus COXSACKIE B Viruses 
A comparative study of the characteristics of two Coxsackie A virus type 16 strains (genotype B)被引量:5
《Science China(Life Sciences)》2012年第4期336-342,共7页YANG ErXia ZHAO Heng ZHANG Ying LIU JianSheng LIAO Yun WANG LiChun CUI PingFang YANG LiXian LIU LongDing DONG ChengHong DONG ShaoZhong SHAO CongWen JIANG Li SUN Le LI QiHan 
supported by the National Basic Research Program of China (Grant No. 2011CB504903);the National Natural Science Foundation of China (Grant No. 81171573);the Important National Science & Technology Specific Projects (Grant No. 2009ZX10004-308);the General Program of Applied Basic Research Programs Commission, Foundation of Yunnan Province (Grant No. 2011FB116)
Coxsackie A virus is one of the major pathogens associated with hand, foot and mouth disease (HFMD). The etiological characteristics of Coxsackie A virus type 16 (CA16) are thought to correlate with the pathological p...
关键词:CA16 strains proliferation kinetics PATHOGENICITY 
短双链RNA在病毒性心肌炎小鼠模型中的抗病毒研究
《现代生物医学进展》2010年第9期1631-1634,共4页王彩虹 姚海兰 刘哲伟 
国家自然科学基金资助项目(30772025);北京市自然科学基金资助项目(7093115);北京市卫生局解剖学研究资助项目(QN2008-013)
目的:通过在小鼠病毒性心肌炎动物模型研究短双链小干扰RNA(small interfering RNA,siRNA)对病毒感染和复制的抑制作用,研究RNAi在治疗病毒性疾病的可行性。方法:利用质粒载体将siRNA转染至HeLa细胞和Balb-c小鼠后感染病毒,荧光显微镜观...
关键词:RNAi 质粒载体 COXSACKIE VIRUS B3 抗病毒作用 
Expression of Coxsackievirus and Adenovirus Receptor in Human Lung Cancer: Possible Clinical Significance被引量:1
《Clinical oncology and cancer researeh》2010年第1期48-54,共7页Lei-na SUN An-kang GU Zhao-li CHEN Zhong-li ZHAN Qian WANG Jun-wen LI Bao-cun SUN 
OBJECTIVE To explore the relationship between CAR and the development of human lung cancer, as well as to provide the basis for the clinical treatment of lung cancer using an adenovirus vector-based gene therapy. METH...
关键词:coxsackie virus and adenovirus receptor protein (CAR) lung cancer IMMUNOHISTOCHEMISTRY RT-PCR Western blot gene therapy. 
黄芪注射液治疗病毒性心肌炎80例观察
《黑龙江医药》2008年第6期67-67,共1页唐亚丽 
病毒性心肌炎(viral myocarditis,VM)是指嗜心性病毒感染引起的,以心肌非特异性间质性炎症为主要病变的心肌炎。临床上以柯萨奇病毒(Coxsackie B组和A组)、埃可(ECHO)病毒、腺病毒、脊髓灰质炎病毒和流感病毒较常见。发病以夏...
关键词:病毒性心肌炎 黄芪注射液 治疗 非特异性间质性炎症 COXSACKIE 嗜心性病毒感染 脊髓灰质炎病毒 柯萨奇病毒 
Role of coxsackievirus and adenovirus receptor in the pathogenesis of dilated cardiomyopathy and its influencing factor被引量:3
《Chinese Medical Journal》2008年第15期1445-1449,共5页ZHANG Shuo JIA Hai-bo GONG Bin-sheng ZHANG Shao-jun LI Xia YU Bo 
This work was supported in part by the National High Tech Development Project of China, the 863 Program (No. 2007AA02Z329), the National Natural Science Foundation of China (No. 30370798, 30571034, and 30570424) and the Key Project of Heilongjiang Province (No. GB07C32402)
Background Although clinical treatment for heart failure and sudden death has been improved over the last few decades, the morbidity and mortality of dilated cardiomyopathy (DCM) have increased. So a better understa...
关键词:dilated cardiomyopathy viral receptor protein interaction gene cluster bicluster 
Analysis of the expression of coxsackievirus and adenovirus receptor in five colon cancer cell lines被引量:3
《World Journal of Gastroenterology》2007年第47期6365-6369,共5页Yassan Abdolazimi Majid Mojarrad Mehrdad Pedram Mohammad Hossein Modarressi 
Supported by the Funds from Medical Sciences/University of Tehran and Iranian Ministry of Health and Medical Education
AIM: To investigate the expression of coxsackievirus and adenovirus receptor (CAR) and adenovirus-mediated reporter gene transfer in five human colon cancer cell lines.METHODS: Expression of CAR-specific mRNA and ...
关键词:Coxsackievirus and adenovirus receptor Adenoviral infection Gene therapy 
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