云南高校图书馆联盟文献共享服务平台- CPT-11

CPT-11: 作品数：120被引量：299H指数：10; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王留兴樊青霞陈樟树李捷陈曦更多>>; 相关机构：法玛西雅厄普约翰美国公司郑州大学第一附属医院中国医学科学院肿瘤医院南京医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家科技重大专项重庆市自然科学基金面向21世纪教育振兴行动计划更多>>

Author correction to"DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS-STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis"[Acta Pharmaceutica Sinica B 12(2022)262-273]: 《Acta Pharmaceutica Sinica B》2023年第7期3177-3177,共1页

DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS-STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis被引量：13: 《Acta Pharmaceutica Sinica B》2022年第1期262-273,共12页Yuanyuan Wang Bin Wei Danping Wang Jingjing Wu Jianhua Gao Haiqing Zhong Yang Sun Qiang Xu Wen Liu Yanhong Gu Wenjie Guo; supported by National Natural Science Foundation of China(81871944,81572389,81922067);Jiangsu 333 project(BRA2016517,China);Natural Science Foundation of Jiangsu Province(BK20190306,China);Jiangsu Province Key Medical Talents(ZDRCA2016026,China);Priority Academic Program Development of Jiangsu Higher Education Institutions and Fundamental Research Funds for the Central Universities(14380114,China)。; Gastrointestinal mucositis is one of the most debilitating side effects of the chemotherapeutic agent irinotecan(CPT-11). Andrographolide, a natural bicyclic diterpenoid lactone, has been reported to possess anti-coli...; 关键词：CPT-11 Gastrointestinal mucositis ANDROGRAPHOLIDE Homologous recombination cGAS-STING

The“Chinese Expert Consensus on the Clinical Application of the Chinese Modified Triplet Combination with Irinotecan(CPT-11),Oxaliplatin(LOHP),Continuous Infusion 5-Fluorouracil,and Leucovorin for Colorectal Cancer”: 《Gastroenterology Report》2021年第4期279-289,I0001,共12页Yanhong Deng Chinese Southwest Oncology Group-the Committee of Colorectal Cancer; supported by The National Key Research and Development Plan of China[2019YFC1316003].; Colorectal cancer is the second most common malignant tumor in China.The FOLFOXIRI regimen,which combines 5-fluorouracil/leucovorin,oxaliplatin,and irinotecan,is a high-intensity and highly effective chemotherapy regi...; 关键词：colorectal cancer FOLFOXIRI China expert consensus

葛根芩连汤三氯甲烷提取物缓解伊立替康所致肠毒性的作用机制分析被引量：6: 《中国实验方剂学杂志》2021年第16期16-23,共8页吴亿晗成颜芬王迪杨晓琴钟雪梅林洁傅超美章津铭胡一晨; 四川省科技支撑计划项目(2020YJ0195);成都中医药大学“杏林学者”学科人才科研提升计划项目;四川省科技创新苗子工程项目(2019051)。; 目的:基于经典名方葛根芩连汤"解表清里、主协热下利"的功效,制备葛根芩连汤三氯甲烷提取物用于缓解伊立替康所致的肠毒性,为经典名方葛根芩连汤的开发与应用提供实验依据。方法:60只小鼠随机分为正常组、模型组、洛哌丁胺组(阳性药盐...; 关键词：葛根芩连汤盐酸伊立替康(CPT-11) 肠毒性氧化应激炎症迟发性腹泻洛哌丁胺肿瘤

Phase 1/2 study of concurrent chemoradiotherapy with weekly irinotecan hydrochloride for advanced/recurrence uterine cancer:A multi-institutional study of Kansai Clinical Oncology Group被引量：1: 《Chinese Journal of Cancer Research》2020年第2期218-227,共10页Satoshi Takeuchi Haruo Kuroboshi Taisuke Mori Kimihiko Ito Eiji Kondo Tsutomu Tabata Yoshio Itani Ryuji Kawaguchi Kyosuke Takeuchi Toshinori Soejima Ryohei Sasaki; supported by grant of Japanese Foundation for Multidisciplinary Treatment of Cancer(JFMC)for Cancer Research in 2005(26 th)。; Objective:Concurrent chemoradiotherapy using cisplatin was thought to be standard treatment for squamous cell carcinoma of cervix,but it had not been effective for adenocarcinoma.Concurrent chemoradiotherapy using iri...; 关键词：Concurrent chemoradiotherapy(CCRT) irinotecan hydrochloride(CPT-11) cervical adenocarcinoma endometrial cancer

Impact of preoperative chemoradiotherapy using concurrent S-1 and CPT-11 on long-term clinical outcomes in locally advanced rectal cancer: 《World Journal of Gastrointestinal Oncology》2020年第3期311-322,共12页Kei Kimura Naohito Beppu Hiroshi Doi Kozo Kataoka Tomoki Yamano Motoi Uchino Masataka Ikeda Hiroki Ikeuchi Naohiro Tomita; BACKGROUND Preoperative chemoradiotherapy regimens using a second drug for locally advanced rectal cancer are still under clinical investigation.AIM To investigate the clinical outcomes of patients with locally advanc...; 关键词：Preoperative chemoradiotherapy Rectal cancer IRINOTECAN Tegafur/gimeracil/oteracil Neoadjuvant chemoradiotherapy Radiation therapy

TPT与CPT-11二线治疗方案对小细胞肺癌患者的疗效比较: 《实用癌症杂志》2019年第1期86-88,共3页韩鹏武淮昌许志强; 目的分析不同二线治疗方案对小细胞肺癌(SCLC)患者临床疗效研究。方法选取SCLC患者226例,将患者分为两组,观察组(113例)采用含TPT治疗方案,对照组(113例)采用为CPT-11治疗方案,观察术后治疗效果,总生存时间(OS),无进展生存时间(PFS),疾...; 关键词：小细胞肺癌二线化疗近期疗效远期生存差异

UGT1A1基因多态性对进展期结直肠癌患者CPT－11治疗的疗效及毒副反应的影响被引量：2: 《浙江临床医学》2018年第8期1338-1340,共3页李建华陈莉莉唐小万章展黄辉杨巧; 浙江省台州市市级科技资金项目（121ky10）; 目的探讨尿苷二磷酸葡萄醛酸转移酶1A1（UGT1A1）基因多态性对进展期结直肠癌（CRC）患者伊立替康（CPT—11）治疗的疗效及毒副反应的影响。方法选取2015年10月至2017年1月诊治的进展期CRC患者149例为观察对象，采集各受试者外周静脉血...; 关键词：尿苷二磷酸葡萄醛酸转移酶1A1 基因多态性结直肠癌 CPT-1 1疗效毒副反应

紫杉醇联合CPT-11治疗中期胃癌的近期临床效果及不良反应: 《包头医学院学报》2018年第6期64-65,共2页陈世超; 目的:研究紫杉醇联合伊立替康(CPT-11)治疗中期胃癌的近期临床效果及不良反应。方法:将105例中期胃癌患者按照入院时间的先后顺序分为对照组(52例)与观察组(53例),观察组采用紫杉醇联合CPT-11治疗、对照组采用紫杉醇治疗,对比两种治疗...; 关键词：中期胃癌紫杉醇伊立替康

LAL test and RPT for endotoxin detection of CPT-11/DSPE-mPEG_(2000) nanoformulation: What if traditional methods are not applicable?: 《Asian Journal of Pharmaceutical Sciences》2018年第3期289-296,共8页Yanan Jin Juanjuan Jia Chan Li Jianqi Xue Jiabei Sun Kaiyuan Wang Yaling Gan Jing Xu Yaqin Shi Xingjie Liang; supported by the National Natural Science Foundation of China [Grant No. 31600812];Strategic Priority Research Program of the Chinese Academy of Sciences [Grant No. XDA09030301];Natural Science Foundation Key Project [Grant No. 31630027, 31430031];the National Distinguished Young Scholars Grant [Grant No. 31225009]; Endotoxin detection is an important step in drug characterization. Herein we found that a chemotherapeutic drug nanoformulation composed of irinotecan hydrochloride(CPT-11) and an amphiphilic molecule DSPE-mPEG_(2000)...; 关键词：IRINOTECAN hydrochloride Endotoxin detection Micelle DSPE-mPEG2000 LIMULUS amebocyte LYSATE assay Rabbit PYROGEN TEST

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