PYROGEN

作品数：7被引量：1H指数：1
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相关领域：医药卫生更多>>
相关机构：四川省消防总队更多>>
相关期刊：《Asian Journal of Pharmaceutical Sciences》《消防技术与产品信息》《Science China Chemistry》《Signal Transduction and Targeted Therapy》更多>>
相关基金：国家自然科学基金更多>>
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A novel alternative for pyrogen detection based on a transgenic cell line
《Signal Transduction and Targeted Therapy》2024年第3期1221-1229,共9页Qing He Chuan-Fei Yu Gang Wu Kai-Qin Wang Yong-Bo Ni Xiao Guo Zhi-Hao Fu Lan Wang De-Jiang Tan Hua Gao Can Wang Gang Chen Xu-Hong Chen Bo Chen Jun-Zhi Wang 
supported by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(research on quality evaluation and standardisation of innovative vaccines,2021-I2M-5-005);the National Key Laboratory of Drug Regulatory Sciences Fund(research on the alternative test for pyrogen detection based on transgenic cells,2023-NIFDC-28).
Pyrogen,often as a contaminant,is a key indicator affecting the safety of almost all parenteral drugs(including biologicals,chemicals,traditional Chinese medicines and medical devices).It has become a goal to complete...
关键词：PYROGEN RABBIT replace 
LAL test and RPT for endotoxin detection of CPT-11/DSPE-mPEG_(2000) nanoformulation: What if traditional methods are not applicable?
《Asian Journal of Pharmaceutical Sciences》2018年第3期289-296,共8页Yanan Jin Juanjuan Jia Chan Li Jianqi Xue Jiabei Sun Kaiyuan Wang Yaling Gan Jing Xu Yaqin Shi Xingjie Liang 
supported by the National Natural Science Foundation of China [Grant No. 31600812];Strategic Priority Research Program of the Chinese Academy of Sciences [Grant No. XDA09030301];Natural Science Foundation Key Project [Grant No. 31630027, 31430031];the National Distinguished Young Scholars Grant [Grant No. 31225009]
Endotoxin detection is an important step in drug characterization. Herein we found that a chemotherapeutic drug nanoformulation composed of irinotecan hydrochloride(CPT-11) and an amphiphilic molecule DSPE-mPEG_(2000)...
关键词：IRINOTECAN hydrochloride Endotoxin detection Micelle DSPE-mPEG2000 LIMULUS amebocyte LYSATE assay Rabbit PYROGEN TEST 
PyroGen——一种消防新技术
《消防技术与产品信息》2001年第4期58-60,共3页冉凯 
关键词：消防 灭火剂 测试 烟雾剂 压力容器 
TNT诱导动、植物微核效应的观察
《卫生研究》1995年第S1期69-70,共2页戴敏 李斌 
ＴＮＴ诱导动、植物微核效应的观察戴敏，李斌（西安兵器工业卫生研究所，西安７１００６１）作者应用蚕豆根尖细胞微核和小鼠骨髓微核测试法，观察ＴＮＴ对动物及植物的诱变效应。结果表明：不同剂量的ＴＮＴ浸泡蚕豆根尖染毒３．５ｈ...
关键词：LIMULUS TEST LAL ENDOTOXIN PYROGEN Memingococcal Polysaccharicde VaccineGroup A 
前言
《卫生研究》1995年第S1期1-1,共1页
前言中国毒理学会工业毒理学专业委员会在中国毒理学会大力支持下，于１９９４年１１月２９日至１２月１日在广州隆重召开成立大会并举行第一次学术交流会。卫生部卫生监督司向大会发来贺信，向工业毒理学专业委员会的成立表示热烈的祝...
关键词：LIMULUS TEST LAL ENDOTOXIN PYROGEN Memingococcal Polysaccharicde VaccineGroup A 
THE EFFECTS OF PERFUSION OF LATERAL VENTRICLE WITH CaCl_2 ON THE FEBRILE RESPONSE AND cAMP CONTENT IN PLASMA AND CEREBROSPINAL FLUID DURING LP-INDUCED FEVER被引量：1
《Science China Chemistry》1991年第3期317-326,共10页张怡 李楚杰 
Artificial cerebrospinal fluid (c.s.f.) containing 40 mmol/L excess calcium was perfus-ed through the lateral ventricles of New Zealand white rabbits in order to reduce the Na^+/Ca^(++) ratio in the brain and the effe...
关键词：ADENOSINE cyclic MONOPHOSPHATE sodium calcium PYROGEN FEVER 
EFFECTS OF SODIUM SALICYLATE ON THE FEBRILE RESPONSE AND INCREASED LEVELS OF CYCLIC AMP IN CEREBRO-SPINAL FLUID DURING ENDOGENOUS PYROGEN-INDUCED FEVER IN RABBITS
《Science China Chemistry》1989年第10期1215-1223,共9页刘晓莹 李楚杰 
To further evaluate the causality between endogenous pyrogen (EP)-induced fever andcyclic adenosine- 3’, 5’- monophosphate (cyclic AMP) level. the effects of sodium salicylate(SS) on the febrile response and increas...
关键词：sodium SALICYLATE PYROGEN FEVER ADENOSINE cyclic MONOPHOSPHATE 
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