This work was supported by the National Natural Science Foundation of China(81988101,81802780,and 81830086);Beijing Municipal Commission of Health and Family Planning Project(PXM2018_026279_000005);Beijing Nova Program(Z191100001119038);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-081);Science Foundation of Peking University Cancer Hospital(2020-8);Funding by Major Program of Shenzhen Bay Laboratory(S201101004);Guangdong Basic and Applied Basic Research Foundation(2019B030302012);the Fund of"San-ming"Project of Medicine in Shenzhen(No.SZSM201812088).
Autophagy is the main degradation pathway to eliminate long-lived and aggregated proteins,aged or malfunctioning organelles,which is essential for the intracellular homeostasis and prevention of malignant transformati...
Beijing University of Chemical Technology-China-Japan Friendship Hospital Joint Fund (PYBZ1710)
Objective: To establish a mouse model of skin squamous cell carcinoma induced by high dose 7, 12-dimethyl-benzodiazepine [a] anthracene, and to provide experimental basis for the prevention and treatment of skin squam...