目的在“骨肉不相亲”理论指导下,比较废用性骨质疏松症大鼠股骨、腓肠肌中果蝇母本抗生存因子蛋白2/3(small mother against decapentaplegic 2/3,Smad2/3)、特异性蛋白1(specificity protein 1,SP1)表达在中医不同治法下的影响,分析...
supported in part by the Intramural Research Program of the National Institute on Aging(NIA),the Center for Alzheimer’s and Related Dementias(CARD),within the Intramural Research Program of the National Institute on Aging and the National Institute of Neurological Disorders and Stroke(AG000546).
Parkinson’s disease(PD)diagnosis is based solely on clinical presentation[1].Therefore,diagnostic and prog-nostic biomarkers are needed.In recent years,seeding aggregation assays(SAA)have demonstrated the ability to ...
supported by CAMS Innovation Fund for Medical Sciences(CIFMS;No.2016-I2M-3-011);the National Natural Science Foundation of China(Nos.81573493 and 81973290);Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study(Z141102004414062);the Key Project of Beijing Natural Science Foundation(No.7181007);National Mega-project for Innovative Drugs and the National Megaproject for Innovative Drugs(No.2018ZX09711001-002-002).
The phenylalanine-tyrosine-dopa-dopamine pathway provides dopamine to the brain.Iin this process,tyrosine hydroxylase(TH)isthe rate-limiting enzyme that hydroxylates tyrosine and generates levodopa(L-dopa)with tetrany...