云南高校图书馆联盟文献共享服务平台- DRONEDARONE

DRONEDARONE: 作品数：17被引量：13H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：马长生罗心平施海明李剑孙铁民更多>>; 相关机构：首都医科大学附属北京安贞医院复旦大学沈阳药科大学安徽省舒城县人民医院更多>>; 相关期刊：《中国民康医学》《中国心脏起搏与心电生理杂志》《医学综述》《心血管病防治知识》更多>>

Dronedarone inhibits the proliferation of esophageal squamous cell carcinoma through the CDK4/CDK6-RB1 axis in vitro and in vivo: 《Frontiers of Medicine》2024年第5期896-910,共15页Bo Li Jing Zhang Yin Yu Yinhua Li Yingying Chen Xiaokun Zhao Ang Li Lili Zhao Mingzhu Li Zitong Wang Xuebo Lu Wenjie Wu Yueteng Zhang Zigang Dong Kangdong Liu Yanan Jiang; funded by the National Natural Science Foundation of China(No.81872335);Central Plains Science and Technology Innovation Leading Talents(No.224200510015);National Natural Science Youth Foundation(No.81902486);Fundamental Research Project of key scientific research in Henan Province(No.23ZX007);Science and Technology Project of Henan Province(No.212102310187)。; Treatment options for patients with esophageal squamous cell carcinoma(ESCC)often result in poor prognosis and declining health-related quality of life.Screening FDA-approved drugs for cancer chemoprevention is a prom...; 关键词：DRONEDARONE CDK4/6 RB1 esophageal squamous cell carcinoma CHEMOPREVENTION PDX model

Site-directed deuteration of dronedarone preserves cytochrome P4502J2 activity and mitigates its cardiac adverse effects in canine arrhythmic hearts被引量：2: 《Acta Pharmaceutica Sinica B》2022年第10期3905-3923,共19页Aneesh V.Karkhanis Gopalakrishnan Venkatesan Ryuichi Kambayashi Jacqueline Wen Hui Leow Marcus Qingrui Han Hiroko Izumi-Nakaseko Ai Goto Jeremy Kah Sheng Pang Boon Seng Soh Pipin Kojodjojo Atsushi Sugiyama Eric Chun Yong Chan; supported by the National University Heart Centre Singapore (NUHCS) Cardiovascular Research Institute (CVRI)Core Fund [Grant NUHSRO/2019/082/Core];SCEPTRE CG Seed Grant [Grant NMRC/CG/M008/2017, Singapore];Singapore Ministry of Education Tier 1 Academic Research Funding [Grant R-148-000-193-112];the National University of Singapore, Department of Pharmacy, Final Year Project Funding [Grant C148-000-003-001] provided to Eric Chun Yong Chan;from Japan Society for the Promotion of Science (JSPS) KAKENHI [grant number 20K16136] provided to Ryuichi Kambayashi; Cytochrome P4502J2(CYP2J2)metabolizes arachidonic acid(AA)to cardioprotective epoxyeicosatrienoic acids(EETs).Dronedarone,an antiarrhythmic drug prescribed for treatment of atrial fibrillation(AF)induces cardiac adver...; 关键词：Arachidonic acid Atrial fibrillation CYP2J2 Drug-induced proarrhythmia Epoxyeicosatrienoic acids Mechanism-based inactivation DRONEDARONE

A Review of Structure Activity Relationship of Amiodarone and Its Derivatives: 《Open Journal of Medicinal Chemistry》2016年第2期37-42,共6页Moiz A. Siddiqui Amjad Khan Mehreen Zaka; Structure Activity Relationship forms the basis of Rational Drug Design in the circles of pharmaceutical and medicinal chemistry. Appropriate knowledge of functional outcomes of structural modifications is crucial in ...; 关键词：AMIODARONE DRONEDARONE Structure-Activity-Relationship

Stability Indicating RP-HPLC Method for the Determination of Dronedarone Hydrochloride and Its Potential Process-Related Impurities in Bulk Drug and Pharmaceutical Dosage Form: 《American Journal of Analytical Chemistry》2013年第6期323-335,共13页Shashikant B. Landge Sanjay A. Jadhav Kapil P. Nimbalkara Anil C. Mali Vijayavitthal T. Mathad; Simple, sensitive and accurate stability indicating analytical method for dronedarone has been developed and validated using RP-HPLC technique. Developed method is used to evaluate the assay and related substances of ...; 关键词：DRONEDARONE RP-LC LC-MS Forced Degradation Validation STABILITY-INDICATING

A Stability Indicating HPLC Method for Dronedarone in Bulk Drugs and Pharmaceutical Dosage Forms: 《American Journal of Analytical Chemistry》2012年第8期544-551,共8页Naresh Tondepu Shakil S. Sait K.V. Surendranath Ravi Kiran Kaja Suresh Kumar; The objective of the current study was to develop a validated, specific and stability-indicating reverse phase HPLC method for the quantitative determination of Dronedarone and its related substances. The determinatio...; 关键词：DRONEDARONE HPLC FORCED DEGRADATION VALIDATION Stability Indicating

上市新药: 《世界临床药物》2012年第4期251-252,共2页; 抗心律失常药物盐酸决奈达隆dronedarone hydrochloride 1商品名 Multaq 2开发与上市厂商本品由赛诺菲一安万特公司研制，于2009年7月在美国首次上市。; 关键词：上市新药 DRONEDARONE 抗心律失常药物安万特公司 2009年决奈达隆商品名赛诺菲

心房颤动2009年进展回顾被引量：5: 《上海医学》2010年第5期397-399,共3页马长生; 关键词：心房颤动 2009年 DRONEDARONE 美国食品药品监督管理局 PREVENT 苄丙酮香豆素钠药物治疗 DEATH

关于新药Dronedarone(MUL TAQ)的重要安全通知: 《中国心脏起搏与心电生理杂志》2010年第2期185-185,共1页余国膺; 关键词：Ⅲ度房室传导阻滞新药安全哺乳妇女病窦综合征心动过缓起搏器 QTC

dronedarone hydrochloride(Multaq)被引量：1: 《中国药物化学杂志》2010年第1期80-80,共1页李姗蓉孙铁民; 关键词：法国赛诺菲-安万特公司抗心律失常药物心房扑动口服片剂

赛诺菲公司将在美国市场投放Multaq用于治疗心房颤动和心房扑动: 《中国新药杂志》2009年第17期1586-1586,共1页; 赛诺菲-安万特公司已经将Multaq^（R）（盐酸决奈达隆，dronedarone hydrochloride）400mg投放美国市场。该化合物用于降低因心血管事件而入院的风险，适用于阵发性和持续性心房颤动（AF）或心房扑动（AFL）、且近期出现AF／AFL以及存...; 关键词：持续性心房颤动心房扑动美国市场赛诺菲 DRONEDARONE 心血管事件治疗风险因素

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