云南高校图书馆联盟文献共享服务平台- RP-LC

RP-LC: 作品数：12被引量：12H指数：2; 导出分析报告; 相关领域：医药卫生理学更多>>; 相关作者：高晓燕赵莉蔺邹振马瑞燕刘颖更多>>; 相关机构：北京中医药大学中国科学院山西农业大学辽宁中医药大学更多>>; 相关期刊：《质谱学报》《Science China Chemistry》《Asian Journal of Traditional Medicines》《解放军药学学报》更多>>; 相关基金：国家自然科学基金国家科技重大专项更多>>

Ion-pair Reversed-phase×Low-pH Reversed-phase Two-dimensional Liquid Chromatography for In-depth Proteomic Profiling: 《Chemical Research in Chinese Universities》2023年第2期260-265,共6页NIU Wenxue LIU Zheyi LIU Jing LAI Can ZHANG Tingting ZHAO Heng WANG Guosheng WANG Fangjun; National Key R&D Program of China(No.2019YFE0119300);National Natural Science Foundation of China(No.32088101);Original Innovation Project of CAS(No.ZDBS-LY-SLH032);Project of Dalian Institute of Chemical Physics,CAS,China(No.DICPI202007).; High-resolution liquid chromatography separation is essential to in-depth proteomic profiling of complex biological samples.Herein,we established an ion-pair reversed-phase×reversed-phase two-dimensional liquid chrom...; 关键词：Two-dimensional liquid chromatography(2DLC) Ion-pair reversed-phase liquid chromatography(IPRP-LC) IPRP×low-pH RP 2DLC PROTEOMICS Mass spectrometry

反相液相色谱-电喷雾-离子阱-飞行时间质谱法定量分析N-非取代肝素/硫酸乙酰肝素被引量：1: 《质谱学报》2019年第3期222-232,I0001,共12页杜佳燕黄海月苏晓明魏峥; 国家自然科学基金(21343013)资助; 肝素和硫酸乙酰肝素由重复的二糖单元组成,其组分和结构与重要的生物病理、生理作用息息相关。这些二糖单元包括含量较高的N-硫酸化葡萄糖胺、N-乙酰化葡萄糖胺和含量较低的N-非取代葡萄糖胺残基。本研究采用2-氨基吖啶酮标记二糖,结合...; 关键词：硫酸乙酰肝素 N-非取代二糖 2-氨基吖啶酮反相液相色谱-电喷雾-离子阱-飞行时间质谱(RP-LC-ESI-IT-TOFMS)

A validated reversed phase HPLC method for determination of process-related impurities in DHDK-loaded mPEG-PLA micelles: 《Asian Journal of Traditional Medicines》2019年第2期82-91,共10页Peipei Yu Jing Hong Ceng Zhou Jingtao Zhao Lin Meng Zhiguo Yu Yunli Zhao; A new compound named DHDK was isolated from Viscum coloratum and identified as (1E,4E)-1,7-bis(4-hydroxyphenyl)hepta -1,4-dien-3-one. DHDK, a new potential anti-tumor drug, was synthesized and prepared poly(ethylene g...; 关键词：DHDK mPEG-PLA RP-LC process-related IMPURITIES validation

肽聚糖识别蛋白AaPGRP-LC参与埃及伊蚊的抗细菌免疫反应被引量：5: 《昆虫学报》2018年第1期25-35,共11页杨青泰赵莉蔺邹振王燕红马瑞燕; 国家自然科学基金青年基金项目(31402013);国家自然科学基金项目(31672291); 【目的】阐明在响应细菌感染的过程中,埃及伊蚊Aedes aegypti体内肽聚糖识别蛋白PGRPLC(Aa PGRP-LC)的功能。【方法】使用实时荧光定量PCR(q PCR)技术分析埃及伊蚊感染阴沟肠杆菌Enterobacter cloacae后不同时间抗菌肽(antimicrobial pe...; 关键词：埃及伊蚊天然免疫细菌肽聚糖识别蛋白抗菌肽

Development and Validation of Stability Indicating Rapid RP-LC Method for Determination of Process and Degradation Related Impurities of Apremilast, an Anti-Inflammatory Drug被引量：1: 《American Journal of Analytical Chemistry》2017年第6期380-394,共15页Shashikant B. Landge Sunil B. Dahale Sanjay A. Jadhav Pavankumar V. Solanki Saroj R. Bembalkar Vijayavitthal T. Mathad; A new, specific, rapid and stability indicating reversed phase liquid chro-matographic (RP-LC) method for the determination of process related and degradation related impurities of Apremilast has been developed and va...; 关键词：Apremilast Stability Indicating RP-LC PDE4 INHIBITOR FORCED DEGRADATION

甲醇-乙腈-水三元流动相系统对胆汁酸类成分的反相色谱保留行为研究被引量：2: 《解放军药学学报》2016年第6期505-507,513,共4页刘颖才谦刘思燚王菲尚展鹏张加余; 国家自然青年科学基金;No.81303206; 目的本文以胆汁酸类成分为例,研究中药系列化学成分在甲醇-乙腈-水三元流动相系统中的色谱保留行为。方法采用LTQ-Orbitrap检测器,研究三元流动相系统中6种胆汁酸类成分的反相色谱保留时间与甲醇/乙腈(m)、乙腈/甲醇(n)的关系。结果在...; 关键词：胆汁酸类三元系统 RP-LC LTQ-Orbitrap

Stability Indicating RP-HPLC Method for the Determination of Dronedarone Hydrochloride and Its Potential Process-Related Impurities in Bulk Drug and Pharmaceutical Dosage Form: 《American Journal of Analytical Chemistry》2013年第6期323-335,共13页Shashikant B. Landge Sanjay A. Jadhav Kapil P. Nimbalkara Anil C. Mali Vijayavitthal T. Mathad; Simple, sensitive and accurate stability indicating analytical method for dronedarone has been developed and validated using RP-HPLC technique. Developed method is used to evaluate the assay and related substances of ...; 关键词：DRONEDARONE RP-LC LC-MS Forced Degradation Validation STABILITY-INDICATING

RP-LC/ESI-MS和HILIC/ESI-MS相结合的大鼠尿液成分检测方法的建立: 《中国实验方剂学杂志》2012年第20期119-121,共3页高晓燕白玉静; 国家自然科学基金项目(81173649/H2817);北京中医药大学自主选题项目(5221010061055); 目的:建立反相液相色谱-电喷雾质谱(RP-LC/ESI-MS)和亲水作用液相色谱-电喷雾质谱(HILIC/ESI-MS)相结合的尿液尽量多化学成分检测数据采集方法。方法:RP-LC最佳色谱条件为Prevail C18色谱柱(4.6 mm×250 mm,5μm),柱温25℃,流动相A 10 m...; 关键词：反相液相色谱-电喷雾质谱亲水作用液相色谱-电喷雾质谱大鼠尿液全成分检测

Synchronized separation of atorvastatin——an antihyperlipidemic drug with antihypertensive, antidiabetic, antithrombotic drugs by RP-LC for determination in combined formulations被引量：1: 《Journal of Pharmaceutical Analysis》2012年第4期285-292,共8页M.V.N.Kumar Talluri Anitha Kalyankar Srinivas Ragampeta; the Department of Pharmaceuticals (Ministry of Chemicals and Fertilizers),New Delhi,for grant of a MS(Pharm.) fellowship; A new rapid and sensitive high performance liquid chromatography (HPLC) method has been developed for the simultaneous determination of atorvastatin—an antihyperlipidemic drug along with most commonly prescribed drug...; 关键词：ATORVASTATIN RP-HPLC ANTIHYPERLIPIDEMIC ANTIHYPERTENSIVE ANTIDIABETIC Antithrombotic drug

Development and Validation of Stability Indicating RP-LC Method for Estimation of Ranolazine in Bulk and Its Pharmaceutical Formulations: 《American Journal of Analytical Chemistry》2012年第5期378-384,共7页Ganji Ramanaiah D. Ramachandran G. Srinivas Jayapal Gowardhane Purnachanda Rao Srilakshmi. V; An isocratic reverse phase liquid chromatography (RP-LC) method has been developed and subsequently validated for the determination of Ranolazine in Bulk and its pharmaceutical formulation. Separation was achieved wit...; 关键词：RANOLAZINE RP-LC VALIDATION DOSAGE FORM

RP-LC