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E-3: 作品数：457被引量：687H指数：11; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：赵福全田超宁显玲郭莹王孝伟更多>>; 相关机构：北京大学中国科学院中国科学院大学中山市理丹电器有限公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家科技支撑计划更多>>

Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice: 《Neural Regeneration Research》2025年第9期2727-2736,共10页Yujia Liu Xue Han Yan Su Yiming Zhou Minhui Xu Jiyan Xu Zhengliang Ma Xiaoping Gu Tianjiao Xia; supported by the National Natural Science Foundation of China,Nos.81730033,82171193(to XG);the Key Talent Project for Strengthening Health during the 13^(th)Five-Year Plan Period,No.ZDRCA2016069(to XG);the National Key R&D Program of China,No.2018YFC2001901(to XG);Jiangsu Provincial Medical Key Discipline,No.ZDXK202232(to XG)。; Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life ...; 关键词：Chil1 hippocampus learning and memory M2 microglia NEUROINFLAMMATION postoperative cognitive dysfunction(POCD) recombinant CHI3L1

A 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran-based near-infrared fluorescence probe for the detection of hydrogen sulfide and imaging of living cells: 《无机化学学报》2025年第3期540-548,共9页ZHANG Linfang YIN Wenzhu YIN Gui; financially supported by the Natural Science Foundation of Jiangsu Province(Grant No.BK20241181);the State Key Laboratory of AnalyticalChemistry for Life Science,School of Chemistry and Chemical Engineering,Nanjing University(Grant No.SKLACLS2419)。; Using 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran(TCF)as a near-infrared fluorescent chromophore,we designed and synthesized a TCF-based fluorescent probe TCF-NS by introducing 2,4-dinitrophenyl ether ...; 关键词：hydrogen sulfide near⁃infrared fluorescence probe cell imaging

基于“既病防变”脾肾同补法调控缺血性脑卒中PI3K/AKT通路相关蛋白表达的研究进展: 《辽宁中医杂志》2024年第12期215-220,I0023,共7页王羽李文武徐青云朱潇苗琦雷烨张怡敏朱慧渊; 国家自然科学基金项目(82174268);中西医结合治疗糖尿病血管病变创新团队项目(2020XKTD-C01);陕西中医药大学校级研究生质量提升工程专项(CXSJ202316)。; 缺血性脑卒中(ischemic stroke,IS)是一种由于脑局部血液供应不足导致的急性脑血管疾病,具有高致残率及致死率的特点。IS的发病机制复杂,涉及细胞凋亡、兴奋性中毒、能量代谢紊乱、氧化应激和炎症反应等方面。在脑缺血半暗带区域,细胞...; 关键词：既病防变脾肾同补磷脂酰肌醇3-激酶(phosphoinositide-3 kinase PI3K)/蛋白激酶B(perine-threonine kinase Akt)通路脑卒中细胞凋亡

Home Monitoring of Estrone-3-Glucuronide (E1-3G) Levels in Two Different Ovarian Stimulation Protocols: A Pilot Study: 《Open Journal of Obstetrics and Gynecology》2024年第10期1640-1656,共17页Iavor K. Vladimirov Desislava Tacheva Evan Gatev Magdalena Rangelova Martin Vladimirov; Background: Studies have shown a strong correlation between the growth of E2 in serum and estrone-3-glucuronide (E1-3G) in urine during ovarian stimulation. Thus, we developed theoretical models for using urinary E1-3...; 关键词：Ovarian Stimulation Monitoring E1-3G Antagonist Protocol PPOS Protocol IVF ART

Dynamics design of a non-natural transcription factor responding to androst-4-ene-3,17-dione: 《Synthetic and Systems Biotechnology》2024年第3期436-444,共9页Ming Zhao Mengkai Hu Rumeng Han Chao Ye Xiangfei Li Tianwen Wang Yan Liu Zhenglian Xue Kun Liu; supported by the Scientific Research Foundation of the Higher Education Institutions of Anhui Province,China(Grant No.2022AH050971);Key R&D and Achievement Transformation Projects(2023yf096);the Scientific Research Start-up Fund for Talents of Anhui Polytechnic University(2022YQQ064).; The production of androst-4-ene-3,17-dione(AD)by the steroidal microbial cell factory requires transcription factors(TFs)to participate in metabolic regulation.However,microbial cell factory lacks effective TFs that c...; 关键词：Protein design Artificial transcription factor Molecular dynamics Steriods Site-mutations

焊缝填充量对15Cr2Mo1耐热钢焊接修复性能的影响: 《焊接》2024年第9期56-61,共6页晏嘉陵齐彦昌刘明星常子金吴赵波崔冰; 【目的】15Cr2Mo1钢属于珠光体耐热钢,在电力和石化等领域应用广泛。但是在长期的使用过程中经常会出现某些区域的裂纹等问题。而补焊工艺具有操作难度不高、代价低和复原能力好等优点。该文旨在揭示焊接修补填充量对焊接接头性能的影...; 关键词：15Cr2Mo1耐热钢补焊填充量 ENiCrFe-3

A Survey on Type-3 Fuzzy Logic Systems and Their Control Applications: 《IEEE/CAA Journal of Automatica Sinica》2024年第8期1744-1756,共13页Oscar Castillo Fevrier Valdez Patricia Melin Weiping Ding; CONAHCYT;Tecnológico Nacional de Mexico/Tijuana Institute of Technology for the support during this research; In this paper,we offer a review of type-3 fuzzy logic systems and their applications in control.The main objective of this work is to observe and analyze in detail the applications in the control area using type-3 fuz...; 关键词：Applications control systems optimization REVIEW type-3 fuzzy logic.

Banxia Xiexin Decoction Alleviated Cerebral Glucose Metabolism Disorder by Regulating Intestinal Microbiota in APP/PS1 Mice: 《Chinese Journal of Integrative Medicine》2024年第8期701-712,共12页GAO Chen-yan QIN Gao-feng ZHENG Ming-cui TIAN Mei-jing HE Yan-nan WANG Peng-wen; Supported by the Special Fund for Basic Scientific Research Operating Fees of Central Universities(No.2019-BUCMXJKY018)。; Objective To identify whether Banxia Xiexin Decoction(BXD)alleviates cerebral glucose metabolism disorder by intestinal microbiota regulation in APP/PS1 mice.Methods Forty-five 3-month-old male APP/PS1 mice were divid...; 关键词：Banxia Xiexin Decoction Alzheimer's disease intestinal microbiota glucagon-like peptide 1 cerebral insulin resistance phosphoinositide-3-kinase/proteinkinase B/glycogen synthase kinase-3β Chinese medicine

银杏叶黄酮对急性脑梗死小鼠血清TNF-α、Cas-pase-3及HIF-1α表达及神经细胞凋亡的影响: 《全科医学临床与教育》2024年第7期600-603,共4页俞海红吴美能; 目的探究银杏叶黄酮通过下调急性脑梗死小鼠血清肿瘤坏死因子-α(TNF-α)、半胱天冬酶(Caspase-3)及低氧诱导因子-1α(HIF-1α)表达对抑制神经细胞凋亡的影响。方法选择健康清洁级6周龄雌性昆明小鼠45只,随机分为观察组、模型组和假手术...; 关键词：银杏叶黄酮急性脑梗死肿瘤坏死因子-α 半胱天冬酶低氧诱导因子-1Α

无缝同步,灵活可靠|信捷电气发布新品薄型控制器一LC5E-32T4: 《智慧工厂》2024年第3期21-21,共1页; 6月3日,信捷电气发布新品薄型控制器一LC5E-32T4。信捷电气是国内较早涉足PLC领域的企业之一,以其稳定的性能和良好的技术支持在行业内建立了良好的口碑。信捷的XC系列PLC广泛应用于包装机械、纺织机械等行业。该款产品具备高速通信,提...; 关键词：高速通信无缝集成标准通信协议停机时间纺织机械薄型包装机械快速定位

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