ERG

作品数：510被引量：1161H指数：14
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Prevalence and clinical application of TMPRSS2-ERG fusion in Asian prostate cancer patients: a large-sample study in Chinese people and a systematic review被引量：4
《Asian Journal of Andrology》2020年第2期200-207,共8页De-Pei Kong Rui Chen Chun-Lei Zhang Wei Zhang Guang-An Xiao Fu-Bo Wang Na Ta Xu Gao Ying-Hao Sun 
This research was funded by the National Nature Science Foundation Youth Project(Grant No.81702514);the National Natural Science Foundation of China(Grant No.81430058);the Clinical Research Project of Shanghai Municipal Commission of Health and Family Planning(Grant No.20184Y0130).
Fusion between the transmembrane protease serine 2 and v-ets erythroblastosis virus E26 oncogene homolog(TMPRSS2-ERG fusion)is a common genetic alteration in prostate cancer among Western populations and has been sugg...
关键词：ASIAN Chinese PROSTATE cancer systematic review TMPRSS2-ERG 
Clinical variability and molecular heterogeneity inprostate cancer被引量：5
《Asian Journal of Andrology》2016年第4期543-548,共6页Jonathan Shoag Christopher E Barbieri 
Prostate cancer is a clinically heterogeneous disease, with some men having indolent disease that can safely be observed, while others have aggressive, lethal disease. Over the past decade, researchers have begun to u...
关键词：cell biology ERG GENOMICS molecular heterogeneity prostate cancer SEQUENCING serine peptidase inhibitor  Kazaltype 1 SPOP tumor profiling 
Two paths for stabilization of ERG in prostate carcinogenesis： TMPRSS2-ERG fusions and speckle-type pox virus and zinc finger protein mutations
《Asian Journal of Andrology》2016年第4期594-595,共2页Laura E Pascal Zhou Wang 
Speckle-type POZ （pox virus and zinc finger protein） protein （SPOP） is anE3 ubiquitin ligase adaptor protein that specifically promotes the ubiquitination and proteasome degradation of proteins. SPOP mutations are...
ETS rearrangements in prostate cancer被引量：5
《Asian Journal of Andrology》2012年第3期393-399,I0005,共8页Mark A Rubin 
Prostate cancer is a clinically and molecularly heterogeneous disease. Understanding the biologic underpinning of prostate cancer is necessary to best determine how biology is associated with the risk of disease progr...
关键词：ETS gene fusion next generation sequencing prostate cancer TMPRSS2.ERG TRANSLOCATION 
Potential for targeted therapy in prostate cancers with ERG abnormalities
《Asian Journal of Andrology》2011年第6期781-782,共2页Sean R Williamson Liang Cheng 
Since the recent identification of recurrent gene fusions in prostate cancer betweenmembers of the ETS family of genes and transmembrane protease, serine 2 （TM PRSS2）, a tremendous amount of interest has developed i...
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