funded by Guizhou Province Science and Technology Plan Project Qiankehe Foundation-ZK[2023]General 360,362;Science and Technology Fund project of Guizhou Provincial Health Commission(gzwkj-2022-09,gzwkj-2023-035);National Natural Science Foundation Cultivation Project of Guizhou Medical University(21NSFCP14,gyfynsfc-2022-25);The PhD Scientific Research Launch Fund Project of the Affiliated Hospital of Guizhou Medical University(gyfybsky-2022-02).
Background:Glioblastoma(GBM)is one of the most malignant types of central nervous system tumors.Oxygen deprivation in the tumor microenvironment is thought to be an important factor in promoting GBM progression.Howeve...
目的探讨溶质载体家族4,成员3(solute carrier family 4,member 3,SLC4A3)在胶质母细胞瘤(glioblastoma,GBM)中的生物学功能和相关的分子机制。方法利用免疫组化分析30例GBM和10例正常脑组织中的SLC4A3表达差异,Kaplan-Meier生存分析评...
supported by the National Key Research and Development Program of China(2022YFA1303000,2017YFA0505602);the National Natural Science Foundation of China(81872408,81872153).
The infiltration of glioblastoma multiforme(GBM)is predominantly characterized by diffuse spread,contributing significantly to therapy resistance and recurrence of GBM.In this study,we reveal that microtubule deacetyl...
Background:To date,there is no effective cure for the highly malignant brain tumor glioblastoma(GBM).GBM is the most common,aggressive central nervous system tumor(CNS).It commonly originates in glial cells such as mi...