Financial support from National Natural Science Foundation of China(Nos.22201202,22171206 and 22371201);Natural Science Foundation of Zhejiang Province(No.LZ23B020001);Open Foundation of Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers(No.E22307);Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(No.2020ZD04);Open Research Fund of Key Laboratory of the Ministry of Education for Advanced Catalysis Materials and Zhejiang Key Laboratory for Reactive Chemistry on Solid Surfaces,Zhejiang Normal University。
A photoredox-catalyzed synthesis ofα,α-difluoromethyl sulfones from sulfur dioxide with readily available gem–difluoroalkenes is reported.This protocol features mild reaction conditions,broad substrate scope and go...
the Guangdong Basic and Applied Basic Research Foundation(2023A1515012657,2024A1515012128);Scientific Research Project of General Universities in Guangdong Province(2022KTSCX046);Zhanjiang Ocean Young Talent Innovation Project(2023E0002,2022E05008);the Fifth-level Research Fund of Guangdong Medical University(4RS23002a,4SG24248G);the Third-level Research Fund of Guangdong Medical University(4RS23002d,4SG22247G);Songshan Lake Medical and Engineering Integration Innovation Project of Guangdong Medical University(4SG22308P)for support.
Herein,we describe a direct route for the synthesis of 3-gem-difluorovinyl lactams through Zn-mediated reductive hydrodehalogenation.Importantly,by using inexpensive deuterium oxide(D_(2)O),the high value-added vicina...
Guangzhou,the historic capital of Lingnan and a trading hub for over a millennium,seamlessly intertwines its rich heritage with the vibrancy of contemporary life.It is a place to get immersed in the rich flavors of lo...
In December 1905,a silent film was screened on Kulangsu Island in Xiamen,Fujian Province,which is the city's first recorded encounter with film,and the beginning of the connection between the city and the film industr...
financial support provided by the National Natural Science Foundation of China(No.22001203).
The incorporation of additional Csp^(3) atoms into candidate drugs may enhance their pharmacological properties.Nevertheless,it remains challenging to construct desired Csp^(3)-Csp^(3) bonds efficiently and practicall...
We thank the National Natural Science Foundation of China(22001233);Zhejiang Provincial Ten Thousand Talent Program(2020R52021)and Zhejiang Normal University for financial support.
Compared to well-established 1,5-HAT of N-centered radicals,the synthetic applications of 1,2-HAT process were scarce due to the high barrier and constrained three-membered transition state.Here,we have developed a no...