GENE_TRANSFECTION

作品数:116被引量:264H指数:9
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相关作者:曾琨杨文秀赵宇王晓谭李华更多>>
相关机构:华东师范大学中国科学院复旦大学南通大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家高技术研究发展计划更多>>
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Modulating the Oxidation Degree of Linear Polyethyleneimine for Preparation of Highly Efficient and Low-cytotoxicity Degradable Gene Delivery Carriers
《Chinese Journal of Polymer Science》2024年第11期1699-1709,I0008,共12页Xiao-Ya Guo Zhi-Yu Yang Hua-Pan Fang Dan-Hua Zhou Xuan Pang Hua-Yu Tian Xue-Si Chen 
financially supported by National Key Research and Development Program of China(No.2021YFB3800900);the National Natural Science Foundation of China(Nos.51925305,51833010 and 52203183);Natural Science Foundation of Xiamen,China(No.3502Z202371004);Fundamental Research Funds for the Central Universities(No.20720230004);the talent cultivation project Funds for the Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(No.HRTP-[2022]52)。
Polyethyleneimine(PEI),as a widely used polymer material in the field of gene delivery,has been extensively studied for modification and shielding to reduce its cytotoxicity.However,research aimed at preparing degrada...
关键词:POLYETHYLENEIMINE Gene delivery Gene transfection Degradable gene carriers 
Effects of Branching Strategy on the Gene Transfection of Highly Branched Poly(β-amino ester)s被引量:2
《Chinese Journal of Polymer Science》2020年第8期830-839,I0006,共11页Yao Wang Chen-Fei Wang Ming Li De-Zhong Zhou Wei Huang Wen-Xin Wang 
This work was financially supported by Science Foundation Ireland(SFI)Principal Investigator Program(No.13/IA/1962);the National Natural Science Foundation of China(Nos.51873179,51903202),and University College Dublin。
Highly branched poiy(β-amino ester)s(HPAEs)have emerged as one type of the most viable non-viral gene delivery vectors,both in vitro and in viva.However,the effects of different branching strategies on the gene trans...
关键词:Gene therapy Non-viral gene vector Highly branched polymer Branching strategy 
Effects of Chirality on Gene Delivery Efficiency of Polylysine被引量:3
《Chinese Journal of Polymer Science》2016年第1期94-103,共10页Bin-wei Zhao Zhuxian Zhou 申有青 
financially supported by the National Basic Research Program(No.2014CB931900);the National Natural Science Foundation of China(No.21090352)
Chirality is a key factor in the biological activity of many biomolecules. Poly(L-lysine)(PLL), a polypeptide synthesized from L-lysine, is one of the mostly used cationic polymers for gene delivery. The effect of...
关键词:Gene delivery Gene transfection Chiral effects Polylysine 
A BIOREDUCIBLE POLYPEPTIDE FOR EFFICIENT GENE TRANSFECTION BOTH IN VITRO AND IN VIVO
《Chinese Journal of Polymer Science》2013年第5期713-713,714-718,共6页Wei Qu Si Chen Shan Ren Xue-jun Jiang Ren-xi Zhuo 张先正 
financially supported by the National Natural Science Foundation of China(Nos.51125014,51233003);the Ministry of Science and Technology of China(2011CB606202)
A disulfide bond containing polypeptide, PolyK6-R8, was designed and prepared by oxidative polymerization between terminal cysteinyl thiol groups of CHK6HC and CR8C. The molar ratio between CHK6HC and CR8C within obta...
关键词:Gene vector POLYPEPTIDE ANGIOGENESIS Limb ischemia. 
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