the grants from the National Key Basic Research Program of China (973 Program)(No.2014CB745201);the National Natural Science Foundation of China (No.81772737);the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDB19040200);the International Cooperation Program of the Chinese Academy of Sciences (No.153D31KYSB20170121);the National Science Foundation Projects of Guangdong Province (No.2017B030301015);the Shenzhen Municipal Government of China (Nos.JCYJ20170413161749433 and JSGG20160301161836370);the Sanming Project of Shenzhen Health and Family Planning Commission (Nos.SZSM201412018 and SZSM201512037);and the High Level University Medical Discipline Construction (No.2016031638).
Natural genetic materials contain many biosynthetic gene clusters encoding potentially valuable natural products,many of which can be used directly without codon optimization or other manipulations.With the developmen...
supported by grants from the National Basic Research Program of China(973 Program,2011CB100104);the National High-Tech R&D Program of China(2011AA100101);the National Natural Science Foundation of China(31071416);the Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences;the National Key Technologies R&D Program of China during the 12th Five-Year Plan period(2013BAD01B02)
Grain number per spike (GNPS) is a major factor in wheat yield breeding. A new wheat germplasm Pubing 3504 shows superior features in spike traits. To elucidate the genetic basis of spike and yield related traits in...
supported by grants from the Hubei Provincial Natural Science Foundation of China(No.2010CDB-06903);National Key Basic Research Program of China(“973”Program,No.2012CB526706);the National Natural Science Foundation of China(Nos.81000771 and 81271694)
PKHD1 gene mutations are found responsible for autosomal recessive polycystic kidney disease(ARPKD). However, it is inconvenient to detect the mutations by common polymerase chain reaction(PCR) because the open re...
supported by the National Basic Research Program of China from the National Ministry of Science and Technology(973 Program)to YK(Grant No.2011CB504300)and to HC(Grant No.2012CB910800);the National Natural Science Foundation of China(Grant No.30930102)to YK;the National High-tech R&D Program of China(863 Program;Grant No.2012AA022502);Key Research Program of the Chinese Academy of Sciences of China(Grant No.KJZD-EW-L06-2)to CZ;the Open Fund of MOE Key Laboratory of Carcinogenesis and Translational Research(Grant No.2014KAIFANG-4)to JB
Esophageal squamous cell carcinoma (ESCC) has a high mortality rate. To determine the molecular basis of ESCC development, this study sought to identify characteristic genome-wide alterations in ESCC, including exon...
grants from the National Basic Research Program of China (973 Program),the National Natural Science Foundation of China,in part by the Peking-Tsinghua Center for Life Sciences and a grant from the Next-Generation BioGreen 21 Program,Rural Development Administration,Republic of Korea
ABSTRACT Recent advances in genome-wide techniques allowed the identification of thousands of non-coding RNAs with various sizes in eukaryotes, some of which have further been shown to serve important functions in man...
supported in part by Grants(to G.G.)from National Natural Science Foundation of China(Grant Nos.81030030,81101262 and 81028011);the National Basic Research Program(973 Program)(No.2012CB910203).
Murine leukemia virus(MLV)-based retroviral vectors is widely used for gene transfer and basic research,and production of high-titer retroviral vectors is very important.Here we report that expression of the Y-box bin...
the National Basic Research Program of China(973 Program)(Grant No.2012CB910900);National Institutes of Health of the USA(GM47850);the National Science Foundation(NSF)Plant Genome Program of the USA(DBI0922604);the Ministry of Agriculture of China(No.2010ZX08010-003).
Light is one of the key environmental signals regulating plant growth and development.Therefore,understanding the mechanisms by which light controls plant development has long been of great interest to plant biologist...
supported by the National High-Tech R&D Program of China (863 Program, 2006AA100104-4);the 948 Project, Ministry of Agriculture, China (2006-G5);the National Natural Science Foundation of China (30971810, 60932008);the National Basic Research Program of China (973 Program, 2009CB118400);the National Genetically Modified Organisms Breeding Major Projects of China (2009ZX08009-088B);the Postdoctoral Fund in Heilongjiang Province, China (LBH-Z07228);the Technology Project of Ministry of Education, Heilongjiang Province, China (11541025);the Technology Project of Harbin, China (2009RFQXN085)
The importance of microRNAs (miRNAs) at the post-transcriptional regulation level has recently been recognized in both animals and plants. In this study, the simple and most effective method of comparative genomic a...
supported by grants from National Natural Sciences Foundation of China (No 30471983, 30872237);Major State Basic Research Development Program of China (973 Program) (No 2007CB512900)
The effects of PEG10 on hydrogen peroxide (H2O2)-induced apoptosis in human normal liver cell line L02 were investigated. The PEG10 gene was transfected into L02 cells by lipofectamine, the positive clone was screen...
supported by the National Hightech R&D Program (863 Program) (No. 2006AA02A308);the National Basic Research Program of China (973 Program) (No. 2006CB910401, 2006CB910801 and 2006CB910600);the National Natural Science Foundation of China (No. 30700988 and 30700356);the National Natural Science Foundation of China for Creative Research Groups (No. 30621063);the Chinese State Key Project Specialized for Infectious Diseases (No. 2008ZX10002-016, 2009ZX10004-103 and 2009ZX09301002);supported by the State Key Laboratory of Proteomics (No. SKLP-Y200801)
Genome sequencing opened the flood gate of "-omics" studies, among which the research about correlations between genomic and phenomic variables is an important part. With the development of functional genomics and s...