HOMING

作品数：93被引量：431H指数：11
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相关作者：宋建梅张天桥段广仁侯明哲张惠丽更多>>
相关机构：北京理工大学哈尔滨工业大学西安工业大学西安交通大学更多>>
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Passive homing method with reinforcement learning for a single hydrophone
《Chinese Journal of Acoustics》2025年第1期18-31,共14页YIN Han CHEN Jianfeng ZHANG Dongzhe 
In order to reduce the stringent volume and cost requirements for underwater unmanned autonomous vehicles(AUVs)when equipped with homing systems,this paper proposes a simple and feasible passive homing method.The prop...
关键词：Single hydrophone Passive homing Reinforcement learning Doppler frequency shift 
A dual drug-loaded tumor vasculature-targeting liposome for tumor vasculature disruption and hypoxia-enhanced chemotherapy
《Chinese Chemical Letters》2025年第1期397-402,共6页Cheng-Zhe Gao Hao-Ran Jia Tian-Yu Wang Xiao-Yu Zhu Xiaofeng Han Fu-Gen Wu 
supported by the Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor(Guangxi Medical University),Ministry of Education(No.GKE-KF202305);the Guangxi Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor,and the Natural Science Foundation of Jiangsu Province(No.BK20211510)。
Vascular disrupting agents(VDAs)can destroy tumor vasculature and lead to tumor ischemia and hypoxia,resulting in tumor necrosis.However,VDAs are easy to induce the upregulation of genes that are associated with cance...
关键词：Tumor-homing peptide LIPOSOME Vascular disrupting agents CHEMOTHERAPY Hypoxia-activated 
Biomimetic cell membrane decorated ZIF-8 nanocarriers with IR-780 and doxorubicin loading for multiple myeloma treatment
《Aggregate》2024年第6期332-339,共8页Guangtao Gao Junyi Che Peipei Xu Bing Chen Yuanjin Zhao 
National Key Research and Development Program of China,Grant/Award Number:2022YFA1105304;National Natural Science Foundation of China,Grant/Award Numbers:32201088,82273954;Natural Science Foundation of Jiangsu Province,Grant/Award Number:BK20210010;Fundings for Clinical Trials from the Affiliated Drum Tower Hospital,Medical School of Nanjing University,Grant/Award Number:2022-LCYJ-MS-16。
Several therapeutic drugs including heptamethine cyanine dye(IR-780),doxorubicin(DOX),and others have exhibited positive outcomes in the treatment of multiple myeloma(MM).However,curing MM is still hampered by undesir...
关键词：BIOMIMETIC bone marrow homing cell membrane drug delivery multiple myeloma PDT/PTT 
Cyanamide-inducible expression of homing nuclease ^(I−)SceI for selectable marker removal and promoter characterisation in Saccharomyces cerevisiae
《Synthetic and Systems Biotechnology》2024年第4期820-827,共8页Liam McDonnell Samuel Evans Zeyu Lu Mitch Suchoronczak Jonah Leighton Eugene Ordeniza Blake Ritchie Nik Valado Niamh Walsh James Antoney Chengqiang Wang Carlos Horacio Luna-Flores Colin Scott Robert Speight Claudia E.Vickers Bingyin Peng 
supported by the Australian Government through the Australian Research Council Centres of Excellence funding scheme(project CE200100029).
In synthetic biology,microbial chassis including yeast Saccharomyces cerevisiae are iteratively engineered with increasing complexity and scale.Wet-lab genetic engineering tools are developed and optimised to facilita...
关键词：Metabolic engineering Genetic circuit Genome engineering Synthetic biology Yeast engineering Promoter engineering 
Enhanced homing of mesenchymal stem cells for in situ niche remodeling and bone regeneration
《Nano Research》2024年第8期7449-7460,共12页Yin Yuan Lijun Chen Jing Yang Sining Zhou Yangxin Fang Qi Zhang Ning Zhang Yifei Li Li Yuan Fan Jia Shuo Ni Charlie Xiang 
supported by the National Key R&D Program of China(No.2022YFA1105603);the Fundamental Research Funds for the Central Universities(No.2022ZFJH003);National Science&Technology Major Project“Key New Drug Creation and Manufacturing Program”(No.2018ZX09201002-005);the National Natural Science Foundation of China(Nos.82200994 and 81900563);CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5-045);Shanghai Post-doctoral Excellence Program(No.2022428).
Mesenchymal stem cells(MSCs)transplantation is a promising strategy for osteoporosis treatment.However,limited sources and poor tissue-homing efficiency limit their clinical capabilities.In this study,we isolated a ki...
关键词：mesenchymal stem cells MICROFLUIDICS bone marrow homing stem cell niche postmenopausal osteoporosis 
A homing rescue gene drive with multiplexed gRNAs reaches high frequency in cage populations but generates functional resistance
《Journal of Genetics and Genomics》2024年第8期836-843,共8页Shibo Hou Jingheng Chen Ruobing Feng Xuejiao Xu Nan Liang Jackson Champer 
supported by laboratory startup funds from Peking University and the Center for Life Sciences,as well as the grants from the National Science Foundation of China(32302455 and 32270672)。
CRISPR homing gene drives have considerable potential for managing populations of medically and agriculturally significant insects.They operate by Cas9 cleavage followed by homology-directed repair,copying the drive a...
关键词：Genedrive Homing drive Rescueelement Population modification Multiplexed gRNAs Resistance alleles Cage study 
Dental pulp regeneration strategies:A review of status quo and recent advances被引量：3
《Bioactive Materials》2024年第8期258-275,共18页Xin-Lu Li Wei Fan Bing Fan 
funded by the National Natural Science Foundation of China(Grant No.82270968&82170943);the Top Youth Talent in Medicine Program of Hubei Province,China.
Microorganisms,physical factors such as temperature or mechanical injury,and chemical factors such as free monomers from composite resin are the main causes of dental pulp diseases.Current clinical treatment methods f...
关键词：Pulp regeneration REVASCULARIZATION SCAFFOLD Growth factor Cell-homing 
Is salmonid migration at risk from chemical information disruption?
《Aquaculture and Fisheries》2024年第3期378-387,共10页Keith B.Tierney Gregory G.Pyle 
Good information is the basis for good decisions.For many invaluable salmon species,chemical information is necessary to guide and fine-tune their migrations to and from freshwater mating grounds.A problem is that sal...
关键词：Salmon migration Ocean ranching Chemical information disruption Homing disruption Olfactory toxicity 
Cell-homing and immunomodulatory composite hydrogels for effective wound healing with neovascularization被引量：2
《Bioactive Materials》2024年第6期185-202,共18页Hayeon Byun Yujin Han Eunhyung Kim Indong Jun Jinkyu Lee Hyewoo Jeong Seung Jae Huh Jinmyoung Joo Su Ryon Shin Heungsoo Shin 
supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.RS-2023-00207746,RS-2023-00207983);a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI);funded by the Ministry of Health&Welfare,Republic of Korea(grant number:HI19C075300).
Wound healing in cases of excessive inflammation poses a significant challenge due to compromised neovascularization.Here,we propose a multi-functional composite hydrogel engineered to overcome such conditions through...
关键词：IMMUNOMODULATION Wound healing NEOVASCULARIZATION Multi-functional nanoparticles Composite hydrogels 
Unexpected divergence in magnetoreceptor MagR from robin and pigeon linked to two sequence variations被引量：5
《Zoological Research》2024年第1期69-78,共10页Shun Wang Peng Zhang Fan Fei Tianyang Tong Xiujuan Zhou Yajie Zhou Jing Zhang Mengke Wei Yanqi Zhang Lei Zhang Yulong Huang Lin Zhang Xin Zhang Tiantian Cai Can Xie 
supported by the National Natural Science Foundation of China(31640001 and T2350005 to C.X.,U21A20148 to X.Z.and C.X.);Ministry of Science and Technology of China(2021ZD0140300 to C.X.);Presidential Foundation of Hefei Institutes of Physical Science,Chinese Academy of Sciences(Y96XC11131,E26CCG27,and E26CCD15 to C.X.,E36CWGBR24B and E36CZG14132 to T.C.)。
Birds exhibit extraordinary mobility and remarkable navigational skills,obtaining guidance cues from the Earth’s magnetic field for orientation and long-distance movement.Bird species also show tremendous diversity i...
关键词：Homing and migration Animal navigation Magnetoreceptor(MagR) Diverse navigation pattern Conserved protein 
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