supported by the National Science Foundation of China(Nos.82071511 and 81120108011);National Key R&D Program of China(No.2017YFE0103700);Shandong Provincial Natural Science Foundation(No.ZR2019ZD32);the Priority Academic Program Development of Jiangsu Higher Education Institutions,and Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX21_2974).
Brain development requires a delicate balance between self-renewal and differentiation in neural stem cells(NSC),which rely on the precise regulation of gene expression.Ten-eleven translocation 2(TET2)modulates gene e...