GP120

作品数：209被引量：309H指数：8
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Curcumin ameliorates hippocampal neuron damage induced by human immunodeficiency virus-1被引量：3
《Neural Regeneration Research》2013年第15期1368-1375,共8页Hongmei Tang Rui Pan Wenli Fang Yanyan Xing Dexi Chen Xiaobao Chen Yuanyuan Yu Junbing Wang Zheng Gong Guoyin Xiong Jun Dong 
supported by the National Natural Science Foundation of China, No. 81171134;Major State Basic Research Development Program (973 Program), No. 2011CB707500;Science and Technology Foundation of Guangzhou, No. 2010Y1-C291;Science and Technology Foundation of Guangdong Province, No. 2010B030700017;Guangdong Medical Research Funds, No. B2010160;Jinan University-National College Students' Innovative Entrepreneurial Training Programs in 2012, No. 1210559039;the Key Laboratory's Open Fund of Jinan University, No. 51212003;College Students' Extracurricular Scientific Innovation and Entrepreneurial Activity Research Topic of Jinan University Challenge Cup in 2012, No. (2012) 42
Our previous studies have shown that infection with the gp120 V3 loop can cause human immunodeficiency virus-1 associated neurocognitive disorders. Curcumin has been shown to improve these effects to some degree, but ...
关键词：neural regeneration traditional Chinese medicine CURCUMIN gp120 V3 loop humanimmunodeficiency virus-1 associated neurocognitive disorders Ca^2＋ SYNAPSE apoptosis grants-supported paper NEUROREGENERATION 
复杂的正选择压力驱动不同细胞嗜性HIV-1的进化
《中国科学：生命科学》2011年第2期109-120,共12页张驰宇 丁娜 陈克平 杨荣阁 
国家自然科学基金(批准号:30600352);国家重点基础研究发展计划(批准号:2006CB504200);病毒学国家重点实验室开放基金(批准号:2009008);江苏大学“拔尖人才培养工程”资助项目
对HIV-1细胞嗜性的研究是理解HIV-1传播和发病机制的关键.通过对HIV-1B和C亚型的R5和X4型病毒的全基因组进行适应性进化分析,发现R5和X4病毒经历了不同的进化方式,并且不同的HIV-1基因受到不同的正选择压力,意味着复杂的自然选择压力驱...
关键词：HIV-1细胞嗜性 适应性进化 正选择位点 R5和X4 GP120 抗原表位 
Complex positive selection pressures drive the evolution of HIV-1 with different co-receptor tropisms被引量：5
《Science China(Life Sciences)》2010年第10期1204-1214,共11页ZHANG ChiYu DING Na CHEN KePing YANG RongGe 
supported by the National Natural Science Foundation of China (Grant No. 30600352);the "Top-notch Personnel" Project of Ji-angsu University, the National Basic Research Program of China (Grant No. 2006CB504200);the Open Research Fund Program of the State Key Laboratory of Virology of China (Grant No. 2009008)
HIV-1 co-receptor tropism is central for understanding the transmission and pathogenesis of HIV-1 infection. We performed a genome-wide comparison between the adaptive evolution of R5 and X4 variants from HIV-1 subtyp...
关键词：HIV-1 co-receptor tropism adaptive evolution positively selected site R5 and X4 GP120 EPITOPES 
A conserved structural motif shared by EIAV gp90 and HIV gp120
《Chinese Science Bulletin》2005年第20期2393-2394,共2页LI Huiguang TONG Xiao SHEN Tao SHEN Rongxian ZHANG Xiaoyan SHAO Yiming 
supported by Ministry of Science and Technology of China(First Stage;Grant No.2001 CCA00600);supported by the National Science Foundation of China(Grant No.30371319).
Both HIV and EIAV belong to the retroviridae family and lentivirus genus. They share considerable simi- larity at gene structural and component level. Hotzel pro- posed that two variable regions and surrounding amino ...
关键词：HIV 爱滋病病毒 传染病 传播途径 基因结构 
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