HFMD

作品数：308被引量：2214H指数：23
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相关机构：中国疾病预防控制中心昆明市儿童医院中国食品药品检定研究院江苏省疾病预防控制中心更多>>
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手足口病疫苗接种策略在疾病防控中的应用效果评估
《中国科技期刊数据库 医药》2025年第2期031-034,共4页李波沙 
本研究旨在评估手足口病疫苗接种策略在疾病防控中的应用效果。方法 选取2022年1月至2023年12月期间,在县级医院儿科门诊及乡镇卫生院登记管理的80例6月龄至5岁儿童作为研究对象,按自愿接种原则分为全程接种组与部分接种组。通过血清学...
关键词：手足口病(HFMD) EV71疫苗 全程接种 免疫应答 疾病防控 
Rational design of a DNA-launched live attenuated vaccine against human enterovirus 71
《Virologica Sinica》2024年第5期812-820,共9页Rong-Rong Zhang Meng-Jiao He Chao Zhou Yan-Peng Xu Wei Tang Tian-Shu Cao Zheng-Jian Wang Mei Wu Tao Ming Yi-Jiao Huang Meng-Xu Sun Hui Zhao Yong-Qiang Deng Xiao-Feng Li Bin Wang Qing Ye Cheng-Feng Qin 
supported by the National Key Research and Development Program of China(2021YFC2302503);the National Natural Science Foundation of China(82241069);Cheng-Feng Qin was supported by the National Science Fund for Distinguished Young Scholars(81925025);the Innovative Research Group from the NSFC(81621005).
Human Enterovirus 71(EV71)has emerged as one of the predominant causative agents of hand,foot and mouth disease(HFMD)with global impact.Despite the inactivated vaccine being licensed,other vaccine candidates based on ...
关键词：Hand foot and mouth disease(HFMD) Human enterovirus 71(EV71) DNA vaccine DNA-launched vaccine Live attenuated vaccine 
Pathogenicity and transcriptomic profiling reveals immunology molecular hallmarks after CA10 virus infection
《Animal Models and Experimental Medicine》2024年第5期717-731,共15页Wanjun Peng Jing Wu Binbin Zhao Lihong Zhang Xin Chen Xiaohui Wei Na Rong Yunlin Han Jiangning Liu 
supported by the National Key Research and Development Program of China(Grant No.2022YFC2303404);the CAMS Innovation Fund for Medical Sciences(CIFMS)grant(2021-1-I2 M-035,2022-I2M-1-020)。
Background:Hand,foot and mouth disease(HFMD)is a common infectious disease caused by viral infection by a variety of enteroviruses,with coxsackievirus A 10(CA10)having become more prevalent in recent years.Methods:In ...
关键词：CA10 HFMD RNA-Seq 
Seroprevalence of neutralizing antibodies against HFMD associated enteroviruses among healthy individuals in Shanghai,China,2022
《Virologica Sinica》2024年第4期694-698,共5页Jiayu Wang Wencheng Wu Wei Wang Jingyi Zhang Jianwei Xiao Mingyi Cai Jiaying Guo Run Li Shuangli Zhu Wanju Zhang Min Chen Zheng Teng 
supported by the key research project of Three-Year Initiative Plan for Strengthening Public Health System Construction in Shanghai(Grant no:GWVI-3,GWVI-11.1-09);approved by the Ethics Committees of Shanghai Municipal Center for Disease Control and Prevention(Ethics Number,2023-44)。
Dear Editor,Hand,foot and mouth disease(HFMD)is one of the most common infectious diseases,particularly in the Asia-Pacific region.In the past two decades,HFMD rises to prominence for its heavy burden,with over one mi...
关键词：ENTEROVIRUS HFMD 
A review of the recombination events,mechanisms and consequences of Coxsackievirus A6
《Infectious Medicine》2024年第2期24-35,共12页Zequn Wang Hongling Wen 
Hand,foot,and mouth disease(HFMD)is one of the most common class C infectious diseases,posing a seri-ous threat to public health worldwide.Enterovirus A71(EV-A71)and coxsackievirus A16(CV-A16)have been regarded as the...
关键词：Genetic recombination CV-A6 Virus evolution ENTEROVIRUS HFMD 
Epidemiology and etiology of hand,foot,and mouth disease in Zhengzhou,China,from 2009 to 2021
《Infectious Medicine》2024年第2期81-89,共9页Bowen Dai Yu Chen Shujie Han Shouhang Chen Fang Wang Huifen Feng Xiaolong Zhang Wenlong Li Shuaiyin Chen Haiyan Yang Guangcai Duan Guowei Li Yuefei Jin 
supported by the National Natural Science Foundation of China(No.82273695,No.82002147,and No.82073618);the Open Research Fund of the National Health Commission Key Laboratory of Birth Defects Prevention&Henan Key Laboratory of Population Defects Prevention(ZD202301).
Background:Hand,foot,and mouth disease(HFMD)is a common childhood infectious disease caused by a variety of enteroviruses(EVs).To explore the epidemiological characteristics and etiology of HFMD in Zhengzhou,China,we ...
关键词：HFMD EPIDEMIOLOGY Enterovirus serotypes EVA-71 CVA-16 
Molecular Epidemiology and Clinical Characteristics of Hand, Foot and Mouth Disease in North Sichuan Region, China, 2018-2023: A Descriptive Study
《Advances in Microbiology》2024年第6期317-332,共16页Zhe Xu Zheng Zhao Linming Fan Manyu Liang Jinglu Chen Jia Zeng Ping Shi Xi’en Gu Zhengdong Li 
Background: Hand, foot and mouth disease (HFMD) remains an important public health problem in China. Many studies on the epidemiological characteristics of HFMD have been reported, but studies in North Sichuan region ...
关键词：ENTEROVIRUS HFMD EPIDEMIOLOGY Clinical Characteristics 
The non-stationary and spatially varying associations between hand,foot and mouth disease and multiple environmental factors:A Bayesian spatiotemporal mapping model study被引量：2
《Infectious Disease Modelling》2024年第2期373-386,共14页Li Shen Minghao Sun Mengna Wei Qingwu Hu Yao Bai Zhongjun Shao Kun Liu 
This work was supported by grants from the National Natural Science Foundation of China(L.S.,grant number:42201448),(K.L.,grant number:82273689);Natural Science Foundation of Hubei Province(L.S.,grant number:2022CFB610).
The transmission and prevalence of Hand,Foot and Mouth Disease(HFMD)are affected by a variety of natural and socio-economic environmental factors.This study aims to quantitatively investigate the non-stationary and sp...
关键词：Hand foot and mouth disease(HFMD) Environmental factors Bayesian spatiotemporal mapping model Non-stationary effects Spatially varying effects 
Coxsackievirus B3 HFMD animal models in Syrian hamster and rhesus monkey
《Virologica Sinica》2024年第2期290-300,共11页Suqin Duan Wei Zhang Yongjie Li Yanyan Li Yuan Zhao Weihua Jin Quan Liu Mingxue Li Wenting Sun Lixiong Chen Hongjie Xu Jie Tang Jinghan Hou Zijun Deng Fengmei Yang Shaohui Ma Zhanlong He 
supported by several key projects,the Medical and Health Science and Technology Innovation Project of the Chinese Academy of Medical Sciences(CIFMS,2016-I2M-2-001);the National Resource Center for Non-Human Primates,Major Science and Technology Special Projects in Yunnan Province,Kunming Science and Technology Innovation and Service Capacity Enhancement Program Key Projects(2016-2-R-07674);the CAMS Innovation Fund for Medical Sciences(CIFMS,2018-I2M-3-002 and 2021-I2M-1-024);the National Key R&D Project of China(2021YFF0702804);Peking Union Medical College-Central University Basic Scientific Research Business Fee(Project number.:3332023079);Yunnan Province Applied Basic Research Special Project-General Project(project number:202401CF070048,202301AT070367).
Coxsackievirus B3(CVB3)is the pathogen causing hand,foot and mouth disease(HFMD),which manifests across a spectrum of clinical severity from mild to severe.However,CVB3-infected mouse models mainly demonstrate viral m...
关键词：Coxsackievirus B3(CVB3) Hand foot and mouth disease(HFMD) Animal models Syrian hamster Rhesus monkey 
Identification of fangchinoline as a broad-spectrum enterovirus inhibitor through reporter virus based high-content screening
《Virologica Sinica》2024年第2期301-308,共8页Qiu-Yan Zhang Jia-Qi Li Qi Li Yang Zhang Zhe-Rui Zhang Xiao-Dan Li Hong-Qing Zhang Cheng-Lin Deng Feng-Xia Yang Yi Xu Bo Zhang 
funded by Guangzhou Municipal Science and Technology Project(202102020241);the National Natural Science Foundation of China(32100110 and 32300132);the National Key Research and Development Program of China(2021YFC2701800,2021YFC2701801).
Hand,foot,and mouth disease(HFMD)is a common pediatric illness mainly caused by enteroviruses,which are important human pathogens.Currently,there are no available antiviral agents for the therapy of enterovirus infect...
关键词：Hand foot and mouth disease(HFMD) ENTEROVIRUS EV-A71 High-content screening Fangchinoline(FAN) 
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