ENTEROVIRUS

作品数：122被引量：487H指数：12
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相关领域：医药卫生更多>>
相关作者：姚昕毛群颖梁争论王一平杜昆更多>>
相关机构：中国疾病预防控制中心重庆医科大学复旦大学中国食品药品检定研究院更多>>
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Exploring enterovirus pathogenesis and cancer therapy potential through reverse genetics
《Biosafety and Health》2025年第1期74-82,共9页Shijin Wang Qing Yu Junfeng Zhou Wanshan Yang Yonggang Wang Haoran Guo Wei Wei 
supported in part by funding from the National Natural Science Foundation of China(32222005,82372226,and 82172246);the Open Project of Key Laboratory of Organ Regeneration and Transplantation,Ministry of Education,Program for JLU Science and Technology Innovative Research Team(2017TD-08);the Fundamental Research Funds for Central Universities.
Over the past decades,oncolytic viruses have emerged as prominent therapeutic agents with significant potential for anticancer treatment.Enteroviruses(EVs)have garnered particular attention due to their specific tropi...
关键词：Reverse genetics Enterovirus(EV) Oncolytic virus(Ov) PATHOGENESIS Tumor immunity 
Seroprevalence of neutralizing antibodies against HFMD associated enteroviruses among healthy individuals in Shanghai,China,2022
《Virologica Sinica》2024年第4期694-698,共5页Jiayu Wang Wencheng Wu Wei Wang Jingyi Zhang Jianwei Xiao Mingyi Cai Jiaying Guo Run Li Shuangli Zhu Wanju Zhang Min Chen Zheng Teng 
supported by the key research project of Three-Year Initiative Plan for Strengthening Public Health System Construction in Shanghai(Grant no:GWVI-3,GWVI-11.1-09);approved by the Ethics Committees of Shanghai Municipal Center for Disease Control and Prevention(Ethics Number,2023-44)。
Dear Editor,Hand,foot and mouth disease(HFMD)is one of the most common infectious diseases,particularly in the Asia-Pacific region.In the past two decades,HFMD rises to prominence for its heavy burden,with over one mi...
关键词：ENTEROVIRUS HFMD 
A review of the recombination events,mechanisms and consequences of Coxsackievirus A6
《Infectious Medicine》2024年第2期24-35,共12页Zequn Wang Hongling Wen 
Hand,foot,and mouth disease(HFMD)is one of the most common class C infectious diseases,posing a seri-ous threat to public health worldwide.Enterovirus A71(EV-A71)and coxsackievirus A16(CV-A16)have been regarded as the...
关键词：Genetic recombination CV-A6 Virus evolution ENTEROVIRUS HFMD 
Epidemiology and etiology of hand,foot,and mouth disease in Zhengzhou,China,from 2009 to 2021
《Infectious Medicine》2024年第2期81-89,共9页Bowen Dai Yu Chen Shujie Han Shouhang Chen Fang Wang Huifen Feng Xiaolong Zhang Wenlong Li Shuaiyin Chen Haiyan Yang Guangcai Duan Guowei Li Yuefei Jin 
supported by the National Natural Science Foundation of China(No.82273695,No.82002147,and No.82073618);the Open Research Fund of the National Health Commission Key Laboratory of Birth Defects Prevention&Henan Key Laboratory of Population Defects Prevention(ZD202301).
Background:Hand,foot,and mouth disease(HFMD)is a common childhood infectious disease caused by a variety of enteroviruses(EVs).To explore the epidemiological characteristics and etiology of HFMD in Zhengzhou,China,we ...
关键词：HFMD EPIDEMIOLOGY Enterovirus serotypes EVA-71 CVA-16 
Molecular Epidemiology and Clinical Characteristics of Hand, Foot and Mouth Disease in North Sichuan Region, China, 2018-2023: A Descriptive Study
《Advances in Microbiology》2024年第6期317-332,共16页Zhe Xu Zheng Zhao Linming Fan Manyu Liang Jinglu Chen Jia Zeng Ping Shi Xi’en Gu Zhengdong Li 
Background: Hand, foot and mouth disease (HFMD) remains an important public health problem in China. Many studies on the epidemiological characteristics of HFMD have been reported, but studies in North Sichuan region ...
关键词：ENTEROVIRUS HFMD EPIDEMIOLOGY Clinical Characteristics 
Caspase-8 activation regulates enterovirus D68 infection-induced inflammatory response and cell death
《Biosafety and Health》2024年第3期171-177,共7页Yuanyuan Zhou Chongtao Zhang Yuhan Zhang Fei Li Jun Shen 
the China National Institute of Food and Drug Control for providing the Fermon strain(GenBank accession number AY426531)and pBluescriptII SK-vector-EV-D6815296;the Shanghai Science and Technology Commission Medical Project(grant 21Y11901300);the Contagious and Infectious Diseases Specialist Alliance(SHDC22021317);the National Key Research and Development Program of China(2022YFC2704900).
Enterovirus D68 (EV-D68) infection causes severe acute respiratory infection and severe neurological complications, such as acute flaccid myelitis (AFM), in children. However, although EV-D68 has pandemic potential, n...
关键词：Enterovirus D68(EV-D68) Inflammatory response Cell death CASPASE-8 
Integration of HiBiT into enteroviruses:A universal tool for advancing enterovirus virology research被引量：1
《Virologica Sinica》2024年第3期422-433,共12页Rui Yu Xiaohong Li Peng Zhang Minghao Xu Jitong Zhao Jingjing Yan Chenli Qiu Jiayi Shu Shuo Zhang Miaomiao Kang Xiaoyan Zhang Jianqing Xu Shuye Zhang 
supported by the National Natural Science Foundation of China(grant nos.82002135 and 82172250).
The utilization of enteroviruses engineered with reporter genes serves as a valuable tool for advancing our understanding of enterovirus biology and its applications,enabling the development of effective therapeutic a...
关键词：ENTEROVIRUS Infectious clones Reporter genes LUCIFERASE Drug screening 
Gp78 regulates PMP22 and causes ER stress and autophagy in EV71-VP1-overexpressing mouse Schwann cells
《BIOCELL》2024年第4期653-664,共12页DANPING ZHU GUANGMING LIU KUAN FENG SUYUN LI DANDAN HU SIDA YANG PEIQING LI 
The study was supported by Guangdong Natural Science Foundation(Grant Numbers 2020A1515010014,2022A1515012411);Science and Technology Key Project for People’s Livelihood of Guangzhou,China(Grant Number 202206010060);Guangzhou Science and Technology Bureau Basic Research Project(SL2024A03J01288);Innovative Project of Children’s Research Institute,Guangzhou Women and Children’s Medical Center,China(Grant Numbers Pre-NSFC-2019-002,NKE PRE-2019-015).
Background:During Enterovirus type 71(EV71)infection,the structural viral protein 1(VP1)activates endoplasmic reticulum(ER)stress associated with peripheral myelin protein 22(PMP22)accumulation and induces autophagy.H...
关键词：Enterovirus type 71 AMFR/gp78 PMP22 AUTOPHAGY Schwann cells 
Identification of fangchinoline as a broad-spectrum enterovirus inhibitor through reporter virus based high-content screening
《Virologica Sinica》2024年第2期301-308,共8页Qiu-Yan Zhang Jia-Qi Li Qi Li Yang Zhang Zhe-Rui Zhang Xiao-Dan Li Hong-Qing Zhang Cheng-Lin Deng Feng-Xia Yang Yi Xu Bo Zhang 
funded by Guangzhou Municipal Science and Technology Project(202102020241);the National Natural Science Foundation of China(32100110 and 32300132);the National Key Research and Development Program of China(2021YFC2701800,2021YFC2701801).
Hand,foot,and mouth disease(HFMD)is a common pediatric illness mainly caused by enteroviruses,which are important human pathogens.Currently,there are no available antiviral agents for the therapy of enterovirus infect...
关键词：Hand foot and mouth disease(HFMD) ENTEROVIRUS EV-A71 High-content screening Fangchinoline(FAN) 
Progressing our knowledge of enterovirus:Epidemiology,diagnosis,prevention,control,and beyond
《Biosafety and Health》2024年第1期3-4,共2页Jing Lu Zexin Tao Yong Zhang 
We are thrilled to present this dedicated issue spotlighting enterovirus infections and health in Biosafety and Health.The articles presented in this issue span the broad spectrum of current research in this vital fie...
关键词：PREVENTION DIAGNOSIS EPIDEMIOLOGY 
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