This study was supported by grants from the National Key Research and Development Program of China(2019ZX09739);National Natural Science Foundation of China(82230060,82271831,81788101,82204258);Chinese Academy of Medical Science Innovation Fund for Medical Sciences(CIFMS,2021-I2M-1-016,2021-I2M-1-017,2021-I2M-1-047,2021-I2M-1-040,2021-I2M-1-016,2021-I2M-1-026);Natural Science Foundation of Beijing(7222263);Beijing Capital Health Development Fund(2020-2-4019);Fundamental Research Funds for the Central Universities(3332022108).
Interleukin-2(IL-2)is a pleiotropic cytokine that orchestrates bidirectional immune responses via regulatory T cells(Tregs)and effector cells,leading to paradoxical consequences.Here,we report a strategy that exploite...
Background Previous studies showed that soluble IL-2Rαis an important marker of cellular immune activation and might be a marker of treatment efficacy for children with brucellosis.However,data regarding adult patien...
the National Natural Science Foundation of China(81400159,81873450,81700196,81672686);Pearl River Nova Program of Guangzhou(201710010161);Sister Institution Net-work Fund of the MD Anderson Cancer Center(to Qingqing Cai);the Fundamental Research Funds for the Central Universities(17ykpy77).
Background:Natural killer/T-cell lymphoma(NKTCL)is a highly aggressive non-Hodgkin lymphoma often resistant to chemotherapy.Serum level of soluble IL-2 receptorα(IL-2Rα)is elevated in NKTCL patients and correlates s...