IMMUNO

作品数：466被引量：1235H指数：18
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相关机构：第四军医大学空军军医大学（第四军医大学）北京大学三峡大学更多>>
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B7-H3 in acute myeloid leukemia:From prognostic biomarker to immunotherapeutic target被引量：1
《Chinese Medical Journal》2024年第21期2540-2551,共12页Xiao Tan Xiangyu Zhao 
supported by grants from the National Natural Science Foundation of China(Nos.82070184 and 82270228);Beijing Nova Program(No.20220484235);Peking University People’s Hospital Research and Development Funds(No.RDL2021-01).
B7-H3(CD276),an immune checkpoint protein of the B7 family,exhibits significant upregulation in solid tumors and hematologic malignancies,exerting a crucial role in their pathophysiology.The distinct differential expr...
关键词：B7-H3(CD276) B7 family Acute myeloid leukemia Immune checkpoint IMMUNOTHERAPY 
Leukocyte immunoglobulin-like receptor B4(LILRB4)in acute myeloid leukemia:From prognostic biomarker to immunotherapeutic target
《Chinese Medical Journal》2024年第22期2697-2711,共15页Muzi Li Xiangyu Zhao 
supported by grants from National Natural Science Foundation of China(Nos.82350105,82270228,and 82070184);Science,Technology&Innovation Project of Xiongan New area(No.2023XACX0004);Beijing Nova Program(No.20220484235);Clinical Medicine Plus X-Young Scholars Project of Peking University,the Fundamental Research Funds for the Central Universities,Peking University People’s Hospital Research and Development Funds(No.RDL2021-01)。
Leukocyte immunoglobulin-like receptor(LILR)B4(also known as ILT3/CD85k)is an immune checkpoint protein that is highly expressed in solid tumors and hematological malignancies and plays a significant role in the patho...
关键词：LILRB4 Leukemia myeloid acute Immune checkpoint Tumor microenvironment Immunotherapy 
Single-cell sequencing and bulk RNA sequencing reveal a cell differentiation-related multigene panel to predict the prognosis and immunotherapy response of hepatocellular carcinoma被引量：1
《Chinese Medical Journal》2023年第4期485-487,共3页Jifeng Liu Qihang Yuan Jie Ren Yiming Li Yunshu Zhang Dong Shang 
supported by The Leading Talent of Hundred,Thousand and Ten Thousand Project of Xingliao Gifted Person Program of Liaoning Province(No.XLYC1905013);Type A Project of Leading Talent’s Innovative Research of Dalian,Capacity-Building Projects of Clinical Discipline of Traditional Chinese Medicine of Health,and Family Planning Commission of Liaoning Province in 2018(No.LNZYXZK201806).
To the Editor:Hepatocellular carcinoma(HCC)is the sixth most common tumor and the third leading cause of cancer death globally in 2020.[1]The lack of early diagnosis and high intratumoral heterogeneity in HCC are impo...
关键词：diagnosis mortality IMMUNOTHERAPY 
COVID-19 in the immunocompromised population:data from renal allograft recipients throughout full cycle of the outbreak in Hubei province,China被引量：3
《Chinese Medical Journal》2022年第2期228-230,共3页Weijie Zhang Fei Han Xiongfei Wu Zhendi Wang Yanfeng Wang Xiaojun Guo Song Chen Tao Qiu Heng Li Yafang Tu Zibiao Zhong Jiannan He Bin Liu Hui Zhang Zhitao Cai Long Zhang Xia Lu Lan Zhu Dong Chen Jiangqiao Zhou Qiquan Sun Zhishui Chen 
This work is funded by a Key Project of Health and Family Planning Commission of Hubei Province of China(No.WJ2019Z007);the National Key Research&Development Program of China(2018YFA0108804);the National Natural Science Foundation of China(Nos.81970650 and 81770753);the Youth Program of National Natural Science Foundation of China(No.81800661);the Fundamental Research Funds for the Central Universities(No.20ykpy34);the China Postdoctoral Science Foundation Funded Project(No.2020M683083).
Coronavirus disease 2019(COVID-19)is an infectious disease caused by a newly discovered coronavirus and has rapidly spread to most of the world and resulted in a global pandemic.However,there is a paucity of informati...
关键词：POPULATION IMMUNO COV 
Antibody prevalence and immunotherapy response in Chinese patients with epilepsy and encephalopathy scores for patients with different neuronal surface antibodies被引量：3
《Chinese Medical Journal》2021年第24期2985-2991,共7页Yu Jia Hui-Fang Wang Meng-Yao Zhang Yu-Ping Wang 
supported by Beijing Municipal Education Commission(Grant No.TJSH20161002502);National Natural Science Foundation of China(Grant No.81771398);Beijing Postdoctoral Research Foundation(No.2021-ZZ-001);Beijing Key Clinical Speciality Excellence Project;National Support Provincial Major Disease Medical Services and Social Capability Enhancement Project.
Background:The scale assessment was helpful in predicting the presence of antibodies to autoimmune encephalitis.This study aimed to evaluate the application of antibody prevalence in Chinese patients with epilepsy and...
关键词：APE2-CHN RITE2-CHN APE2 RITE2 Neuronal surface antibody Immunotherapy 
Immunotherapy-related toxicity in lung cancer: clinical characteristics and managing strategy被引量：1
《Chinese Medical Journal》2021年第7期780-782,共3页Wen-Xin Luo Lan Yang Wei-Min Li 
National Natural Science Foundation of China to Wei-Min Li(No.81871890)。
Worldwide,lung cancer is the most common malignancy and the leading cause of cancer-related death.After the era of chemotherapy,radiotherapy,and molecular-targeted therapy,the treatment of advanced lung cancer has ent...
关键词：LUNG clinical cancer 
Changes in immunological function after treatment with transarterial chemoembolization plus radiofrequency ablation in hepatocellular carcinoma patients被引量：15
《Chinese Medical Journal》2013年第19期3651-3655,共5页GUAN Hai-tao WANG Jian YANG Ming SONG Li TONG Xiao-qiang ZOU Ying-hua 
Background Different strategies for hepatocellular carcinoma （HCC） may have distinct effects on the immune system.The aim of this research was to investigate changes in the immunological function after transcatheter...
关键词：hepatocellular carcinoma transcatheter arterial chemoembolization radiofrequency ablation CD4＋ CD8 ＋ immunologic function 
Clinical and immunopathological features of patients with lupus hepatitis被引量：8
《Chinese Medical Journal》2013年第2期260-266,共7页ZHENG Ru-hua WANG Jin-hui WANG Shu-bing CHEN Jie GUAN Wei-ming CHEN Min-hu 
Background Lupus hepatitis is yet to be characterized based on its clinical features and is often difficult to differentially diagnose from other liver diseases. We aimed to elucidate clinical, histopathological and i...
关键词：lupus liver INJURY IMMUNOPATHOLOGY 
Association of immunophenotypic characterization of peripheral lymphocytes with different clinical phenotypes of tuberculosis in Chinese Han children被引量：4
《Chinese Medical Journal》2012年第2期275-280,共6页Xiao Jing Sun Lin Wu Xi-rong Miao Qing Jiao Wei-wei Shen Chen Shen Dan Feng Wei-xing Liu Fang Shen A-dong 
Background Very few researchers have studied the changes in peripheral lymphocyte patterns in adult tuberculosis （TB） and even less researches have been conducted in pediatric TB.In this study,we obtained blood samp...
关键词：CHILD IMMUNOPHENOTYPING LYMPHOCYTES MENINGITIS TUBERCULOSIS 
Matrix metalloproteinase-9 was involved in the immuno-modulatory defect of mesenchymal stem cell from chronic myeloid leukemia patients被引量：3
《Chinese Medical Journal》2011年第16期2423-2430,共8页ZHU Xi-shan SHI Wei AN Guang-yu ZHANG Hong-mei SONG Yu-guang LI You-bin 
Background Overwhelming evidences on chronic myeloid leukemia （CML） indicate that patients harbor quiescent CML stem cells that are responsible for blast crisis. While the hematopoietic stem cell （HSC） origin of C...
关键词：chronic myeloid leukemia mesenchymal stem cell immune regulation matrix metalloproteinase-9 
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