IMMUNO

作品数：466被引量：1235H指数：18
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Immunoassay development guidelines for neurodegenerative disorders:lessons from a failed pS129-α-synuclein electrochemiluminescence immunoassay
《Neural Regeneration Research》2025年第10期2906-2908,共3页Hash Brown Taha Alanna Morris 
An aging population is a double-edged sword.On one hand,advancements in biotechnology and healthcare allow more people to enjoy longer lives.On the other hand,increases in the aging population accompany a surge in age...
关键词：AGING DEGENERATIVE necessarily 
Dendritic cells immunotargeted therapy for atherosclerosis
《Acta Pharmaceutica Sinica B》2025年第2期792-808,共17页Zhaohui Li Yanyan Yang Jinbao Zong Bei Zhang Xiaolu Li Hongzhao Qi Tao Yu Yongxin Li 
supported by National Natural Science Foundation of China(No.82270442 and 82370425,China);Taishan Scholar Program of Shandong Province(No.tsqn202408156);the Natural Science Foundation of Shandong Province(No.ZR2022MH027,China).
Atherosclerosis,a chronic inflammatory disease,is markedly influenced by both immune and inflammatory reactions throughout its progression.Dendritic cells,as pivotal antigen-presenting entities,play a crucial role in ...
关键词：Dendritic cell ATHEROSCLEROSIS IMMUNOTHERAPY INFLAMMATION Delivery 
Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms
《Cancer Communications》2025年第1期15-42,共28页Jiali Yao Linlin Ji Guang Wang Jin Ding 
National Natural Science Foundation of China,Grant/Award Numbers:82473431,82303184;Innovation Program of Shanghai Municipal Education Commission,Grant/Award Number:20230548;Shanghai Key Laboratory of Cell Engineering,Grant/Award Number:14DZ2272300;Medical Discipline Construction Project of Pudong Health Committee of Shanghai,Grant/Award Number:PWYgf2021-08。
Neutrophils are key mediators of the immune response and play essential roles in the development of tumors and immune evasion.Emerging studies indicate that neutrophils also play a critical role in the immunotherapy r...
关键词：immune resistance IMMUNOTHERAPY NEUTROPHIL tumor Tumor microenvironment 
Comprehensive molecular characterization to predict immunotherapy response in advanced biliary tract cancer:a phase II trial of pembrolizumab
《Oncology Research》2025年第1期57-65,共9页RYUL KIM JOO KYUNG PARK MINSUK KWON MINAE AN JUNG YONG HONG JOON OH PARK SUNG HEE LIM SEUNG TAE KIM 
supported by the MISP program at Merck Sharp&Dohme Corp.,USA;a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI);funded by the Ministry of Health&Welfare,Republic of Korea(Grant Number:HR20C0025).
Background:Immune checkpoint inhibitors(ICIs)are effective in a subset of patients with metastatic solid tumors.However,the patients who would benefit most from ICIs in biliary tract cancer(BTC)are still controversial...
关键词：Pembrolizumab Whole-exome sequencing Whole-transcriptome sequencing Biliary tract cancer 
Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response
《World Journal of Clinical Oncology》2025年第1期43-52,共10页Zhi-Jian Tang Yuan-Ming Pan Wei Li Rui-Qiong Ma Jian-Liu Wang 
Supported by National Key Technology Research and Developmental Program of China,No.2022YFC2704400 and No.2022YFC2704405.
BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment responses.AIM To predict prognosis and immunotherapy response in patients diagnose...
关键词：Ovarian cancer MITOCHONDRIA PROGNOSIS IMMUNOTHERAPY Neural network 
HNRNPC as a pan-cancer biomarker and therapeutic target involved in tumor progression and immune regulation
《Oncology Research》2025年第1期83-102,共20页YUEZHOU ZHANG ZHAO ZHANG JINXIN DONG CHANGAN LIU 
Background:Aberrant expression of RNA-binding proteins(RBPs)has been linked to a variety of diseases,including hematological disorders,cardiovascular diseases,and multiple types of cancer.Heterogeneous nuclear ribonuc...
关键词：Heterogeneous nuclear ribonucleoprotein C(HNRNPC) Pan-cancer analysis Tumor immunity Prognostic biomarker Immunotherapeutic target Hepatocellular carcinoma 
Prevalence and Risk Factors for Cryptosporidium Diarrhea among Children Aged Five Years and below in Selected Health Institutions in Abakaliki, South-East Nigeria
《Advances in Microbiology》2025年第1期1-18,共18页Onyinye Ifeyinwa Nkeiru Onyekachi Uduma Victor Uduma Emeka Donald Ogiji Kenechukwu Emmanuel Onyekachi Nweke Chinedu Idakari Nneka Marian Chika-Igenyi Chidiebere Brown Ene Chinwe Ifeoma Joe-Akunne Chinedum Christabel Amagwu Shedrach Chikezie Emeribe Felix Osogu Edegbe Bolaji Abdulazeez Akanni Chibuike Sunday Ugwuocha Kingsley Achi Adamma Gloria Olisa Uzochukwu Chimdindu Ibe Chiedozie Kingsley Ojide 
Background: Diarrheal diseases have globally decreased over the past few decades, yet they remain one of the top three causes of mortality in children under five years, especially in sub-Saharan Africa and Nigeria. Se...
关键词：Cryptosporidium hominis Immunofluorescent Antibody Test Ziehl-Neelsen Stain 
TDERS,an exosome RNA-derived signature predicts prognosis and immunotherapeutic response in clear cell renal cell cancer:a multicohort study
《Journal of the National Cancer Center》2024年第4期382-394,共13页Aimin Jiang Ying Liu Ziwei He Wenqiang Liu Qiwei Yang Yu Fang Baohua Zhu Xiaofeng Wu Huamao Ye Bicheng Ye Shunxiang Gao Le Qu Wenhao Xu Peng Luo Linhui Wang 
funded by grants from the National Natural Science Foundation of China(grant numbers:82002664,81872074,81772740,82173345 and 82373154);the Hanghai Jiading District Health Commission Scientific Research Project Youth Fund(grant num-ber:2020-QN-02);the Meng Chao Talent Training Plan-Youth Re-search Talent Training Program of Eastern Hepatobiliary Surgery Hos-pital and the Foundation for Distinguished Youths of Jiangsu Province(grant number:BK20200006).
Background:Tumor-derived exosomes are involved in tumor progression and immune invasion and might func-tion as promising noninvasive approaches for clinical management.However,there are few reports on exosom-based mar...
关键词：Renal cell carcinoma EXOSOME Non-invasive biopsy Immunotherapy response Multiomics PLOD2 
Immuno-electron microscopy localizes Caenorhabditis elegans vitellogenins along the classic exocytosis route
《Life Metabolism》2024年第6期17-32,共16页Chao Zhai Nan Zhang Xi-Xia Li Xue-Ke Tan Fei Sun Meng-Qiu Dong 
funded by the National Natural Science Foundation of China(NSFC-ISF 32061143020 to M.Q.D.,31925026 to F.S.,and 31501160 to X.X.L.);the Ministry of Science and Technology of the People's Republic of China(institutional grants to NIBS,Beijing,a fund of the National High-Level Talents Special Support Program to M.Q.D.);Beijing Municipal Science and Technology Commission(institutional grants to NIBS,Beijing and a fund for cultivation and development of innovation base to M.Q.D.).
Vitellogenins(VITs)are the most abundant proteins in adult hermaphrodite Caenorhabditis elegans.VITs are synthesized in the intes-tine,secreted to the pseudocoelom,matured into yolk proteins,and finally deposited in o...
关键词：VITELLOGENIN YOLK immuno-EM EXOCYTOSIS Caenorhabditis elegans 
Zen Meditation and the Neuro-Immuno-Endocrine Axis
《Health》2024年第12期1242-1249,共8页Huijun Z. Ring Ryan Kern 
The Neuro-Immuno-Endocrine axis coordinates interactions between the nervous, immune, and endocrine systems to maintain physiological homeostasis and respond to internal and external stimuli. Dysregulation of this axi...
关键词：Endocrine Balance Immune Modulation Inflammatory Response Neurological Response Neuro-Immuno-Endocrine Axis Stress Reduction Zen Meditation 
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