INFUSION

作品数：399被引量：909H指数：13
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  • 期刊=Signal Transduction and Targeted Therapyx
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A phase 2 pilot study of umbilical cord blood infusion as an adjuvant consolidation therapy in elderly patients with acute myeloid leukemia
《Signal Transduction and Targeted Therapy》2025年第1期384-393,共10页Jinzeng Wang Xiaoyang Li Ping Liu Yao Dai Hongming Zhu Yunxiang Zhang Min Wu Yunying Yao Mingzhu Liu Shuting Yu Fangying Jiang Shuai Wang Haoran Mu Bo Jiao Hua Yan Wen Wu Yang Shen Junming Li Shengyue Wang Ruibao Ren 
supported by the Shanghai Science and Technology Development Funds(No.20Z11900200 to R.R.);Key Project of National Natural Science Foundation of China(No.82230088 to R.R.);National Key Research and Development Program of China(No.2019YFA0905900 to J.L.;No.2019YFA0905902 to S.W.),National Natural Science Foundation of China(No.82170147 to R.R.;No.82370157 to J.L.;No.81970134 and 82170111 to P.L.);Shanghai Collaborative Innovation Program on Regenerative Medicine and Stem Cell Research(No.2019CXJQ01 to R.R.);the Samuel Waxman Cancer Research Foundation(to R.R.).
Acute myeloid leukemia(AML)is an aging-related malignancy,with patients aged≥60 years old facing significantly poorer prognosis.Umbilical cord blood(UCB)has emerged as a promising source with effective anti-aging rol...
关键词：INFUSION PATIENTS ADJUVANT 
Camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and hepatic artery infusion chemotherapy for hepatocellular carcinoma in Barcelona Clinic Liver Cancer stage C (TRIPLET): a phase Ⅱ study被引量：28
《Signal Transduction and Targeted Therapy》2023年第11期5556-5562,共7页Tian-Qi Zhang Zhi-Jun Geng Meng-Xuan Zuo Ji-Bin Li Jin-Hua Huang Zi-Lin Huang Pei-Hong Wu Yang-Kui Gu 
Guangzhou Science and Technology Program Civic Technology Research Plan(No.201903010037);Guangdong Natural Science Foundation(No.2020A1515011539).
Hepatic arterial infusion chemotherapy(HAIC)using a combination of oxaliplatin,fluorouracil,and leucovorin(FOLFOX)has shown promise for hepatocellular carcinoma(HCC)patients classified under Barcelona Clinic Liver Can...
关键词：INFUSION transient BARCELONA 
Anti-BCMA CAR T-cell therapy CT103A in relapsed or refractory AQP4-IgG seropositive neuromyelitis optica spectrum disorders:phase 1 trial interim results被引量：15
《Signal Transduction and Targeted Therapy》2023年第2期683-691,共9页Chuan Qin Dai-Shi Tian Luo-Qi Zhou Ke Shang Liang Huang Ming-Hao Dong Yun-Fan You Jun Xiao Ying Xiong Wen Wang Hao Pang Jing-Jing Guo Song-Bai Cai Di Wang Chun-Rui Li Min Zhang Bi-Tao Bu Wei Wang 
Chimeric antigen receptor(CAR)T-cell therapy that targets B-cell maturation antigen(BCMA)have great potentials in autoimmune diseases and could be novel therapeutics for relapsed/refractory neuromyelitis optica spectr...
关键词：AQP4 BCMA INFUSION 
Human umbilical cord mesenchymal stem cells for psoriasis:a phase 1/2a,single-arm study被引量：11
《Signal Transduction and Targeted Therapy》2022年第9期3512-3522,共11页Lamei Cheng Siqi Wang Cong Peng Xiao Zou Chao Yang Hua Mei Chuang Li Xian Su Na Xiao Qi Ouyang Mi Zhang Qiaolin Wang Yan Luo Minxue Shen Qun Qin Honglin Wang Wu Zhu Guangxiu Lu Ge Lin Yehong Kuang Xiang Chen 
This study was sponsored by The National Key Research and Development Project of China(2020YFA0112900,2018YFC0117004);The National Natural Science Foundation of China(82073447,81573049);The Key Research and Development Program of Hunan Province(2018SK2082);The Research and Development Project of Hunan Guangxiu High-tech Life Technology Co,Ltd(2019RES08).
Psoriasis is a common,chronic immune-mediated systemic disease that had no effective and durable treatment.Mesenchymal stem cells(MSCs)have immunomodulatory properties.Therefore,we performed a phase 1/2a,single-arm cl...
关键词：PSORIASIS INFUSION PHASE 
Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19:a phase 1 clinical trial被引量：26
《Signal Transduction and Targeted Therapy》2020年第1期1010-1016,共7页Fanping Meng Ruonan Xu Siyu Wang Zhe Xu Chao Zhang Yuanyuan Li Tao Yang Lei Shi Junliang Fu Tianjun Jiang Lei Huang Peng Zhao Xin Yuan Xing Fan Ji-Yuan Zhang Jinwen Song Dawei Zhang Yanmei Jiao Limin Liu Chunbao Zhou Markus Maeurer Alimuddin Zumla Ming Shi Fu-Sheng Wang 
supported by The National Key R&D Program of China(2020YFC0841900,2020YFC0844000);The Innovation Groups of the National Natural Science Foundation of China(81721002);The National Science and Technology Major Project(2017YFA0105703);The Military Emergency Research Project for COVID-19(BWS20J006);The Project for Innovation of Military Medicine of China(16CXZ045).
No effective drug treatments are available for coronavirus disease 2019(COVID-19).Host-directed therapies targeting the underlying aberrant immune responses leading to pulmonary tissue damage,death,or long-term functi...
关键词：PATIENTS INFUSION CLINICAL 
Irreversible electroporation plus allogenic Vγ9Vδ2 T cells enhances antitumor effect for locally advanced pancreatic cancer patients被引量：4
《Signal Transduction and Targeted Therapy》2020年第1期402-410,共9页Mao Lin Xiaoyan Zhang Shuzhen Liang Haihua Luo Mohammed Alnaggar Aihua Liu Zhinan Yin Jibing Chen Lizhi Niu Yong Jiang 
supported by grants from the National Natural Science Foundation of China(no.81971895);the NSFC-Guangdong Joint Foundation of China(no.U1601225);the Guangdong Provincial Key Laboratory Construction Project of China(no.2017B030314034).
Immunotherapy has limited efficacy against locally advanced pancreatic cancer(LAPC)due to the presence of an immunosuppressive microenvironment(ISM).Irreversible electroporation(IRE)can not only induce immunogenic cel...
关键词：PATIENTS INFUSION CANCER 
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