This study was supported by grants from the National Natural Science Foundation of China (No. 31530020, No. 81471601, and No. 81671602) and the Beijing Nova Program (No. Z 171100001117025).
Background: Increased serurn autoantibodies against interleukin-2 (anti-IL-2 autoantibodies) were reported in patients with systemic lupus crythematosus (SLE) and in patients receiving IL-2 therapy. This study ai...
Background:Altered immunoresponse is associated with tumorigenesis and cancer progression.This study assessed the levels of tumor-infiltrating CD3^+ or CD8^+ T lymphocytes and interleukin-2 (IL-2) protein in radi...
Interleukins and intert-erons are distinct groups of cytokines that are upregulated after viral infection in humans and have been recogmzed as having antltumor activity. For example, high-dose interleukin-2 (IL-2) h...
This study was supported by grants from the National Natural Science Foundation of China (No. 30972516), and the Health Department of Hebei Province (No. 20110086 and 20090004).
Background Peg-lnterferon-a treatment is expensive and associated with considerable adverse effects, selection of patients with the highest probability of response is essential for clinical practice. The objective of ...
Background Candidal balanoposthJtis (CB) is a common male genital infection. Autoimmune mechanisms may play an important role in the pathOgenesis of CB. Interleukin-2 (IL-2) is an important molecule in cell-mediat...
Tuberculosis (TB) is the most common cause of death in infectious diseases; it is estimated that approximately 2 million people per year die of TB. The present available TB vaccine is a live attenuated strain, Mycoba...
Background CC chemokine receptor 3 (CCR3), expressed on some inflammatory cells, is a member of the chemokine receptor family. Its ligand is eotaxin/CCL11. In this research, we studied the expression and function o...
Objective To study the effects of vitamin E on the proliferation and collagen synthesis of rat hepatic stellate cells treated with interleukin-2 (IL-2 ) or tumor necrosis factor-α (TNF-α).Methods Hepatic stellate ce...
To investigate the therapeutic efficacy of compound immunotherapy of tumor deri ved heat shock protein 70 (HSP70) and interleukin 2 (IL 2) on tumor bearing m ice, and to provide reference for translating this stra...
OBJECTIVE: To study the effect and mechanism of the peripheral blood mononuclear cell (PBMC) invasion by HBV on artificial immunization in newborns. METHODS: Fifty-two newborns of HBsAg positive mothers were immunized...