INTERLEUKIN-2

作品数:156被引量:353H指数:9
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相关领域:医药卫生更多>>
相关作者:鲁亚玲许建峰段梅欣武永利魏雪红更多>>
相关机构:北京中医药大学中国科学技术大学中国科学院上海生命科学研究院宁夏医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家科技重大专项更多>>
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Clinical Relevance of Autoantibodies against Interleukin-2 in Patients with Systemic Lupus Erythematosus被引量:3
《Chinese Medical Journal》2018年第13期1520-1526,共7页Miao Shao Xiao-Lin Sun He Sun Jing He Rui-Jun Zhang Xia Zhang Zhan-Guo Li 
This study was supported by grants from the National Natural Science Foundation of China (No. 31530020, No. 81471601, and No. 81671602) and the Beijing Nova Program (No. Z 171100001117025).
Background: Increased serurn autoantibodies against interleukin-2 (anti-IL-2 autoantibodies) were reported in patients with systemic lupus crythematosus (SLE) and in patients receiving IL-2 therapy. This study ai...
关键词:AUTOANTIBODY INTERLEUKIN-2 Systematic Lupus Erythematosus 
Prognostic Significance of Tumor-infiltrating CD8^+ or CD3^+ T Lymphocytes and Interleukin-2 Expression in Radically Resected Non-small Cell Lung Cancer被引量:11
《Chinese Medical Journal》2015年第1期105-110,共6页Chuntao Tian Shixin Lu Qingxia Fan Weijie Zhang Shunchang Jiao Xiao Zhao Zhiyong Wu Liang Sun Liuxing Wang 
Background:Altered immunoresponse is associated with tumorigenesis and cancer progression.This study assessed the levels of tumor-infiltrating CD3^+ or CD8^+ T lymphocytes and interleukin-2 (IL-2) protein in radi...
关键词:IMMUNOHISTOCHEMISTRY Immunological Parameters Non-small Cell Lung Cancer Prognostic Factors 
Acute interstitial pneumonia caused by interleukin-2 and interferon α-2b therapy for renal cell carcinoma: a case report and clinical study被引量:1
《Chinese Medical Journal》2014年第23期4154-4156,共3页Zhang Hanyu Xie Miaorong 
Interleukins and intert-erons are distinct groups of cytokines that are upregulated after viral infection in humans and have been recogmzed as having antltumor activity. For example, high-dose interleukin-2 (IL-2) h...
关键词:interferon alfa-2b INTERLEUKIN-2 acute interstitial pneumonia 
Gene polymorphisms of interleukin-28, p21-activated protein kinases 4, and response to interferon-α based therapy in Chinese patients with chronic hepatitis B被引量:7
《Chinese Medical Journal》2013年第9期1726-1731,共6页YU Feng-xue ZHANG Xiao-lin WANG Yan-ping MA Ning DU Hong MA Jian-min LIU Dian-wu 
This study was supported by grants from the National Natural Science Foundation of China (No. 30972516), and the Health Department of Hebei Province (No. 20110086 and 20090004).
Background Peg-lnterferon-a treatment is expensive and associated with considerable adverse effects, selection of patients with the highest probability of response is essential for clinical practice. The objective of ...
关键词:chronic hepatitis B gene polymorphisms interleukin-28 interferon-a p21-activated protein kinase 4 
Expression of interleukin-2 in Candidal balanoposthitis and its clinical significance被引量:10
《Chinese Medical Journal》2011年第17期2776-2778,共3页CHEN Jun ZHOU Yun-xiao JIN Xiao-dong CHEN Shan-wen 
Background Candidal balanoposthJtis (CB) is a common male genital infection. Autoimmune mechanisms may play an important role in the pathOgenesis of CB. Interleukin-2 (IL-2) is an important molecule in cell-mediat...
关键词:INTERLEUKIN-2 Candidal balanoposthitis 
Cloning and expression of the fusion protein of interleukin-2 and ESAT6 in Mycobacterium bovis Bacillus Calmette Guérin strain被引量:2
《Chinese Medical Journal》2005年第9期762-765,共4页FANXiong-lin WANGLi-mei LUXian-yu TUZhi-guang SHIChang-hong XUZhi-kai 
ThisworkwassupportedbygrantsfromNationalNaturalScienceFoundationofChina(No. 30170855 ) and863 ProjectProgram(No. 2001AA215201)
Tuberculosis (TB) is the most common cause of death in infectious diseases; it is estimated that approximately 2 million people per year die of TB. The present available TB vaccine is a live attenuated strain, Mycoba...
关键词:Mycobacterium tuberculosis INTERLEUKIN-2 VACCINE Bacillus Calmette Guérin ESAT6 
Apoptosis in human germinal centre B cells by means of CC chemokine receptor 3 expression induced by interleukin-2 and interleukin-4被引量:1
《Chinese Medical Journal》2005年第8期665-670,共6页ZHANGQiu-ping XIELuo-kun ZHANGLi-jun TANJin-quan 
Background CC chemokine receptor 3 (CCR3), expressed on some inflammatory cells, is a member of the chemokine receptor family. Its ligand is eotaxin/CCL11. In this research, we studied the expression and function o...
关键词:apoptosis · B cells · CC chemokine receptor 3 · interleukin-2 · interleukin-4 
Effects of vitamin E on the proliferation and collagen synthesis of rat hepatic stellate cells treated with IL-2 or TNF-α被引量:5
《Chinese Medical Journal》2003年第3期153-155,共3页展玉涛 王宇 魏来 陈红松 
ThisworkwassupportedbyagrantfromNational 863Program(No 2 0 0 1AA2 1715 1)
Objective To study the effects of vitamin E on the proliferation and collagen synthesis of rat hepatic stellate cells treated with interleukin-2 (IL-2 ) or tumor necrosis factor-α (TNF-α).Methods Hepatic stellate ce...
关键词:hepatic stellate cells vitamin E tumor necrosis factor-α. Interleukin-2 
Therapeutic efficacy of tumor-derived heat shock protein 70 immunoth erapy combining interleukin-2 on tumor-bearing mice被引量:2
《Chinese Medical Journal》2003年第2期288-291,共4页傅庆国 孟凡东 沈晓东 郭仁宣 
To investigate the therapeutic efficacy of compound immunotherapy of tumor deri ved heat shock protein 70 (HSP70) and interleukin 2 (IL 2) on tumor bearing m ice, and to provide reference for translating this stra...
关键词:neoplasm  · heat shock protein 70 · i nterleukin 2 
Mechanism of peripheral blood mononuclear cell invasion by HBV on artificial immunization in newborns被引量:4
《Chinese Medical Journal》2002年第9期1380-1382,153-154,共3页岳亚飞 孟金来 张树林 
OBJECTIVE: To study the effect and mechanism of the peripheral blood mononuclear cell (PBMC) invasion by HBV on artificial immunization in newborns. METHODS: Fifty-two newborns of HBsAg positive mothers were immunized...
关键词:DNA  Viral Hepatitis B Surface Antigens Hepatitis B Vaccines Hepatitis B virus Humans IMMUNIZATION IMMUNOGLOBULINS Infant  Newborn INTERLEUKIN-2 Leukocytes  Mononuclear 
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