This work was supported by the National Funds for Distinguished Young Scientists of China (No. 81325009) and National Nature Science Foundation of China (No. 81270168, No. 81227901), (Feng Cao BWS12J037), Innovation Team granted by Ministry of Education PRC (IRT1053), National Basic Research Program of China (2012CB518101). Shaanxi Province Program (2013K12-02-03, 2014KCT-20). The authors declare no conflict of interest.
Background The induced pluripotent stem cell (iPSC) has shown great potential in cellular therapy of myocardial infarction (MI), while its application is hampered by the low efficiency of cardiomyocyte differentia...
supported by grants from the National Major Project of the People's Republic of China (Nos. 2011ZX08002-004 and 2011ZX08010-004);the Wuhan Science and Technology Project (No. 201260523185);the International Scientific and Technological Cooperation Project of Ministry of Science and Technology of China (No. 2009DFB20290)
Summary: Previous studies have shown that STAT3 plays a vital role in the genesis and progression of cancer. In this study, we investigated the relationship between the JAK2/STAT3 signalling pathway and germacrone-in...