Supported by the National Natural Science Foundation of China under Grant Nos 10775038 and 10975045, the Hebei Provincial Natural Science Foundation under Grant Nos C2009000029 and C2009001104, and Subsidization for Construction Term of Key Subjects in Universities and Colleges of Hebei Province.
We perform the density functional theory and Brownian dynamics simulations based on the three-dimensional structure of the WT KcsA channel and its mutants. Our data suggest that the electrostatic interactions between ...