supported by the National Basic Research Program of China(Nos.2020YFA0710700 and 2018YFA0208900);the National Natural Science Foundation of China(Nos.82172758,81873919,and 81801810).
Although transcatheter arterial chemo-embolization(TACE)plays a key role on clinical treatment of hepatocellular carcinoma(HCC),it was greatly limited by the poor synergistic effect between chemotherapeutics and physi...
supported by Key Project of Chinese National Programs for Fundamental Research and Development(973 Program)(No.2009CB522900,No.2015CB554501);the Project of Three-Year Action Plan for development of traditional Chinese medicine in Shanghai(No.ZY(2018-2020)-CCCX-2004-01);Shanghai Clinical Research Center for Acupuncture and Moxibustion(No.20MC1920500)。
Objective:The objective of this study is to systematically review and analyze the efficacy of acupuncture for pain caused by primary liver cancer(PLC).Materials and Methods:We searched databases,including PubMed,Medli...
supported by the National Key Project of Research and Development Program of China(Grant No.2016YFC1302503);the National Key Basic Research Program of China“973 Program”(Grant No.2015CB554000);the State Key Project Specialized for Infectious Diseases of China(Grant Nos.2008ZX10002-015 and 2012ZX10002008-002);the US National Institutes of Health(Grant No.UM1 CA173640).
Objective:This study aimed to determine whether dietary fat intake increased liver cancer risk in Chinese women from a prospective population-based cohort.Methods:A total of 72,704 Chinese women were followed up from ...
financially supported by the National Natural Science Foundation of China(51673189,51973215,51833010and 51520105004);Ministry of Science and Technology of China(Project 2018ZX09711003-012);the Program of Scientific Development of Jilin Province(20170101100JC,20180520207JH,20190103112JH,China);supported by NIH grant CA198999(USA)
Primary bile acids were reported to augment secretion of chemokine(C-X-C motif)ligand16(CXCL16)from liver sinusoidal endothelial cells(LSECs)and trigger natural killer T(NKT)cellbased immunotherapy for liver cancer.Ho...
This work was supported by the Leading Investigator Program of Shanghai municipal government(17XD1401100);the National Key Basic Research Program(973 Program,2015CB554005);the National Natural Science Foundation of China(81372655,81472224 and 81672326)to HCS.
Liver cancer,mostly hepatocellular carcinoma(HCC),is the second leading cause of cancer mortality globally.Most patients were diagnosed at an advanced stage,and systemic therapy is the standard of care.All the approve...
supported by the National Key Project of Research and Development Program of China(No.2016YFC1302503);the National Key Basic Research Program of China“973 Program”(No.2015CB554000);the State Key Project Specialized for Infectious Diseases of China(No.2008ZX10002-015 and No.2012ZX10002008-002).
Aim:To describe the global pattern and trend of liver cancer survival,using data from the population-based studies or cancer registration.Methods:By searching CNKI,Wanfang Data,PubMed,Web of Science,EMBASE and SEER.Al...
This work was supported by the Anhui Natural Science Foundation (No. 1708085QH183), Natural Science Foundation of China (Nos. 81302863, 31390433, and 91542000), and the Ministry of Science and Technology of China (973 Program, No. 2013CB944902).
γδ T cells display unique developmental, distributional, and functional patterns and can rapidly respond to various insults and contribute to diverse diseases. Different subtypes of γδ T cells are produced in the...
supported,in part,by the Precision Medical Research Program from Ministry of Science and Technology of China(Grant No.YL 2017YFC0908400);National Science and Technology Major Project for Infectious Disease and Funding(Grant No.YL 17-163-12-ZT-005-095-01);Science and Technology Commission in Ministry of National Defense of China(Grant No.YL 17-163-12-ZT-005-095-01);Xinwei Wang was supported by the intramural research program of the Center for Cancer Research,National Cancer Institute of the United States;Junfang Ji was supported by the Thousand Young Talents Plan of China,National Natural Science Foundation of China(Grant No.81672905)
Introduction Primary liver cancer, the second most common cause of cancer related death worldwide, presents ethnic, etiological, sex, and geographical diversity2 (Figure 1A). At the histological level, liver cancer ...
supported by grants from the National Key Basic Research Program (Grant No. 2013CB910504);the National Natural Science Foundation of China (Grant No. 81125016 and 81472565)
Liver cancer, primarily hepatocellular carcinoma(HCC), is a major cause of cancer-related death worldwide. HCC is a suitable model of inflammation-induced cancer because more than 90% of HCC cases are caused by liver ...
ACKNOWLEDGEMENTS This work was supported in part by funding from the Ministry of Science and Technology of China (973 grant No. 2015CB553402), National Natural Science Foundation of China (grant No. 31470532), the Tsinghua University-Peking University Center for Life Sciences (CLS), the Tsinghua-Janssen Scholarship and research grant, and the Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases.
Hepatitis B is a well-known risk factor for the development of fiver cancer and is closely associated with patient morbidity and mortality. Viral mutants and variants have the potential to evade immune response and pr...