MAGNETIC_RESONANCE_IMAGING

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Advances in magnetic nanoparticle-based magnetic resonance imaging contrast agents
《Nano Research》2023年第11期12531-12542,共12页Huan Zhang Xiao Li Liu Hai Ming Fan 
supported by the National Key R&D Program of China(Nos.2021YFA1201401 and 2021YFA1201402);the National Natural Science Foundation of China(Nos.82202306,82150301,82072063,and 31901003);the Guangdong Natural Science Foundation(No.2023A1515012508);the China Postdoctoral Science Foundation(Nos.2022M723700 and 2023T160776).
Magnetic resonance imaging(MRI)has revolutionized medical imaging diagnostics with the advantages of non-invasive nature,absence of ionizing radiation,unrestricted penetration depth,high-resolution imaging of soft tis...
关键词:magnetic resonance imaging magnetic nanoparticle blood pool contrast agents biochemically-targeted contrast agents stimulus-responsive contrast agents 
Gadolinium-containing semiconducting polymer nanoparticles for magnetic resonance/fluorescence dual-modal imaging and photothermal therapy of oral squamous cell carcinoma
《Nano Research》2023年第2期2808-2820,共13页Xiao Pan Antian Gao Yanni Hu Ziyang Hu Chen Xie Zitong Lin 
supported by the National Natural Science Foundation of China(Nos.82201135,22174070,and 61905122);Nanjing Clinical Research Center for Oral Diseases(No.2019060009);General project of Jiangsu Provincial Health Commission(No.M2021077);Scientific research fund of Jiangsu Medical Association(No.SYH-3201150-0007(2021002));the Natural Science Foundation of Jiangsu Province(No.BK20190735).
Oral squamous cell carcinoma(OSCC)is the most common malignant tumor of the oral and maxillofacial region.Due to its unique location,earlier and more accurate diagnosis and more minimally invasive treatment of OSCC is...
关键词:oral squamous cell carcinoma magnetic resonance imaging fluorescence imaging dual-modal imaging photothermal therapy semiconducting polymer nanoparticles 
Manganese-doped mesoporous polydopamine nanoagent for T1-T2 magnetic resonance imaging and tumor therapy
《Nano Research》2023年第2期2991-3003,共13页Xiuqi Hou Xi Yang Yanwen Xu Jiayin Lin Fang Zhang Xiaohui Duan Sitong Liu Jie Liu Jun Shen Xintao Shuai Zhong Cao 
supported by the National Natural Science Foundation of China(Nos.51933011 and 31971296);the Key Areas Research and Development Program of Guangzhou(No.202007020006);Guangdong Basic and Applied Basic Research Foundation(No.2020A1515010523);Guangzhou Science and Technology Bureau(No.202102010181);Guangdong Provincial Key Laboratory of Sensing Technology and Biomedical Instrument(Sun Yat-sen University,No.2020B1212060077);approved by the Institutional Animal Care and Use Committee at Sun Yat-sen University(SYSU-IACUC-2021-000225).
Theranostic nanodrugs combining magnetic resonance imaging(MRI)and cancer therapy have attracted extensive interest in cancer diagnosis and treatment.Herein,a manganese(Mn)-doped mesoporous polydopamine(Mn-MPDA)nanodr...
关键词:mesoporous polydopamine magnetic resonance imaging T1-T2 dual-mode NO gas therapy immunotherapy 
Versatile nanocomposite augments high-intensity focused ultrasound for high-efficacy sonodynamic therapy of glioma被引量:2
《Nano Research》2022年第10期9082-9091,共10页Yingyan Zheng Dejun She Huihui Huang Lin Lin Sunhui Chen Yiping Lu Li Liu Zhiqing Pang Bo Yin 
supported by the Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01);ZJ Lab,Shanghai Center for Brain Inspired Technology,and the Youth Program of National Natural Science Foundation of China(No.81901697).
High-intensity focused ultrasound(HIFU),with inherent advantages of improved ultrasonic depth and low off-target damage,holds the promising capability for glioma treatment,but the relatively long therapeutic time and ...
关键词:GLIOMA sonodynamic therapy high intensity focused ultrasound tumor microenvironment responsive magnetic resonance imaging 
Dual-modality magnetic resonance/optical imaging-guided sonodynamic therapy of pancreatic cancer with metal-organic nanosonosensitizer被引量:1
《Nano Research》2022年第7期6340-6347,共8页Yingli Chen Bo Yin Zhuang Liu Han Wang Zi Fu Xiuru Ji Wei Tang Dalong Ni Weijun Peng 
We greatly acknowledge the financial support from the National Natural Science Foundation of China(No.82102190);Shanghai Municipal Education Commission--Gaofeng Clinical Medicine Grant Support(No.20191805);the Foundation of National Facility for Translational Medicine(Shanghai)(No.TMSK-2021-122);this work was also supported,in part,by China Postdoctoral Science Foundation(No.2020M681326);Shanghai Sailing Program(No.19YF1410100);Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01);ZJ Lab,Shanghai Center for Brain-Inspired Technology.
Sonodynamic therapy(SDT)has been more attractive to carry out oncology treatments in recent years.However,imagingguided sonodynamic therapeutic nanomedicine is still a shortage in SDT development.In this work,we desig...
关键词:pancreatic tumor sonodynamic therapy THERANOSTICS magnetic resonance imaging 
Multifunctional oxygen-enriching nano-theranostics for cancer-specific magnetic resonance imaging and enhanced photodynamic/photothermal therapy被引量:1
《Nano Research》2020年第5期1389-1398,共10页Li Zhang Zhe Yang Jinghua Ren Li Ba Wenshan He Chun-Yuen Wong 
The work described in this paper was supported by the Research Grants Council of Hong Kong SAR(CityU 11228316,11207117,T42-103/16-N);City University of Hong Kong(Nos.7005096 and 7005257);the National Natural Science Foundation of China(No.81874084).
The combination of photodynamic therapy(PDT)and photothermal therapy(PTT)has attracted much interest in recent years,but non-specific distribution of photosensitizers and intrinsic tumor hypoxic microenvironment have ...
关键词:hypoxia relief MnO2 nano-sheet photodynamic therapy photothermal therapy magnetic resonance imaging 
Special interstitial route can transport nanoparticles to the brain bypassing the blood-brain barrier被引量:2
《Nano Research》2019年第11期2760-2765,共6页Nan Hu Xiaoli Shi Qiang Zhang Wentao Liu Yuting Zhu Yuqing Wang Yi Hou Yinglu Ji Yupeng Cao Qian Zeng Zhuo Ao Quanmei Sun Xiaohan Zhou Xiaochun Wu Dong Han 
the Chinese Academy of Sciences(No.ZDKYYQ20190002)。
Nowadays,nanoparticles(NPs)are considered to be ideal tools for bioimaging and drug delivery.Although increasing research has focused on NP biodistribution,transportation in the interstitial architecture has been negl...
关键词:NANOPARTICLES interstitial stream mass transportation blood-brain barrier magnetic resonance imaging 
A facile fabrication route for binary transition metal oxide-based Janus nanoparticles for cancer theranostic applications被引量:2
《Nano Research》2018年第10期5735-5750,共16页M. Zubair Iqbal Wenzhi Ren Madiha Saeed Tianxiang Chen Xuehua Ma Xu Yu Jichao Zhang Lili Zhang Aiguo Li Aiguo Wu 
This project is financially supported by the National Natural Science Foundation of China (Nos. 81550110258 and U1432114), Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund (the second phase) (to Aiguo Wu, under Grant No. U1501501), by the China Postdoctoral Research program (No. 2014M561799), by the Zhejiang Provincial Natural Science Foundation of China (No. BSH1401038), by the Hundred Talents Program of the Chinese Academy of Sciences (No. 2010-735), by the Natural Science Foundation of Ningbo (No. 2015A610080), by the Key Breakthrough Program of the Chinese Academy of Sciences (No. KGZD-EW-T06), and Bureau of Science and Technology of Ningbo Municipality City (Nos. 2014B82010, 2015Bl1002, and 2015C50004). The authors appreciate the cooperation of Ningbo University, Shanghai Niumag Company for their time and help. Dr M. Zubair Iqbal is thankful to Chinese Academy of for awarding a PIFI and CAS- TWAS postdoctoral fellowship (No. 2014FFGB0004). Furthermore, the authors also acknowledged Shanghai Synchrotron Radiation Facility at Line BL15U (No. h15sr0021) used for X-ray fluorescence imaging.
Janus nanoparticles (JNPs) have multiple configurations for molecular imaging, targeting, and therapeutic effects on cancers; these properties have made these particles attractive for biomedical applications. Noneth...
关键词:Janus nanostructures manganese oxide magnetic resonance imaging photodynarnic therapy breast cancer 
Polyethylene glycol-modified cobalt sulfide nanosheets for high-performance photothermal conversion and photoacoustic/magnetic resonance imaging被引量:3
《Nano Research》2018年第5期2436-2449,共14页Zhenglin Li Zhuo Li Lei Chen Ying Hu Shaoshan Hu Zhaohua Miao Ye Sun Flemming Besenbacher Miao Yu 
This work was financially supported by the National Natural Science Foundation of China (NSFC) (Nos. 21473045 and 51401066), the Fundamental Research Funds from the Central University (PIRSOF HIT A201503), and the State Key Laboratory of Urban Water Resource and Environment, the Harbin Institute of Technology (No. 2018DX04).
Theranostic nanoagents that integrate the diagnoses and therapies within a single nanomaterial are compelling in their use for highly precise and efficient antitumor treatments. Herein, polyethylene glycol (PEG)-mod...
关键词:cobalt sulfide nanosheets theranostic agent photoacoustic imaging magnetic resonance imaging photothermal therapy 
Doxorubicin-Ioaded Fe3O4@MoS2-PEG-2DG nanocubes as a theranostic platform for magnetic resonance imaging- guided chemo-photothermal therapy of breast cancer被引量:5
《Nano Research》2018年第5期2470-2487,共18页Wensheng Xie Qin Gao Dan Wang Zhenhu Guo Fei Gao Xiumei Wang Qiang Cai Si-shen Feng Haiming Fan Xiaodan Sun Lingyun Zhao 
This study was supported by the National Natural Science Foundation of China (NSFC) (No. 81671829).
Molybdenum disulfide (MoS2), a typical transition-metal dichalcogenide, has attracted increasing attention in the field of nanomedicine because of its preeminent properties. In this study, magnetic resonance imaging...
关键词:iron oxide nanocubes molybdenum disulfide multimodality therapy photothermal therapy nanotheranostics 
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