supported by the National Key R&D Program of China(Nos.2021YFA1201401 and 2021YFA1201402);the National Natural Science Foundation of China(Nos.82202306,82150301,82072063,and 31901003);the Guangdong Natural Science Foundation(No.2023A1515012508);the China Postdoctoral Science Foundation(Nos.2022M723700 and 2023T160776).
Magnetic resonance imaging(MRI)has revolutionized medical imaging diagnostics with the advantages of non-invasive nature,absence of ionizing radiation,unrestricted penetration depth,high-resolution imaging of soft tis...
supported by the National Natural Science Foundation of China(Nos.82201135,22174070,and 61905122);Nanjing Clinical Research Center for Oral Diseases(No.2019060009);General project of Jiangsu Provincial Health Commission(No.M2021077);Scientific research fund of Jiangsu Medical Association(No.SYH-3201150-0007(2021002));the Natural Science Foundation of Jiangsu Province(No.BK20190735).
Oral squamous cell carcinoma(OSCC)is the most common malignant tumor of the oral and maxillofacial region.Due to its unique location,earlier and more accurate diagnosis and more minimally invasive treatment of OSCC is...
supported by the National Natural Science Foundation of China(Nos.51933011 and 31971296);the Key Areas Research and Development Program of Guangzhou(No.202007020006);Guangdong Basic and Applied Basic Research Foundation(No.2020A1515010523);Guangzhou Science and Technology Bureau(No.202102010181);Guangdong Provincial Key Laboratory of Sensing Technology and Biomedical Instrument(Sun Yat-sen University,No.2020B1212060077);approved by the Institutional Animal Care and Use Committee at Sun Yat-sen University(SYSU-IACUC-2021-000225).
Theranostic nanodrugs combining magnetic resonance imaging(MRI)and cancer therapy have attracted extensive interest in cancer diagnosis and treatment.Herein,a manganese(Mn)-doped mesoporous polydopamine(Mn-MPDA)nanodr...
supported by the Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01);ZJ Lab,Shanghai Center for Brain Inspired Technology,and the Youth Program of National Natural Science Foundation of China(No.81901697).
High-intensity focused ultrasound(HIFU),with inherent advantages of improved ultrasonic depth and low off-target damage,holds the promising capability for glioma treatment,but the relatively long therapeutic time and ...
We greatly acknowledge the financial support from the National Natural Science Foundation of China(No.82102190);Shanghai Municipal Education Commission--Gaofeng Clinical Medicine Grant Support(No.20191805);the Foundation of National Facility for Translational Medicine(Shanghai)(No.TMSK-2021-122);this work was also supported,in part,by China Postdoctoral Science Foundation(No.2020M681326);Shanghai Sailing Program(No.19YF1410100);Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01);ZJ Lab,Shanghai Center for Brain-Inspired Technology.
Sonodynamic therapy(SDT)has been more attractive to carry out oncology treatments in recent years.However,imagingguided sonodynamic therapeutic nanomedicine is still a shortage in SDT development.In this work,we desig...
The work described in this paper was supported by the Research Grants Council of Hong Kong SAR(CityU 11228316,11207117,T42-103/16-N);City University of Hong Kong(Nos.7005096 and 7005257);the National Natural Science Foundation of China(No.81874084).
The combination of photodynamic therapy(PDT)and photothermal therapy(PTT)has attracted much interest in recent years,but non-specific distribution of photosensitizers and intrinsic tumor hypoxic microenvironment have ...
the Chinese Academy of Sciences(No.ZDKYYQ20190002)。
Nowadays,nanoparticles(NPs)are considered to be ideal tools for bioimaging and drug delivery.Although increasing research has focused on NP biodistribution,transportation in the interstitial architecture has been negl...
This project is financially supported by the National Natural Science Foundation of China (Nos. 81550110258 and U1432114), Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund (the second phase) (to Aiguo Wu, under Grant No. U1501501), by the China Postdoctoral Research program (No. 2014M561799), by the Zhejiang Provincial Natural Science Foundation of China (No. BSH1401038), by the Hundred Talents Program of the Chinese Academy of Sciences (No. 2010-735), by the Natural Science Foundation of Ningbo (No. 2015A610080), by the Key Breakthrough Program of the Chinese Academy of Sciences (No. KGZD-EW-T06), and Bureau of Science and Technology of Ningbo Municipality City (Nos. 2014B82010, 2015Bl1002, and 2015C50004). The authors appreciate the cooperation of Ningbo University, Shanghai Niumag Company for their time and help. Dr M. Zubair Iqbal is thankful to Chinese Academy of for awarding a PIFI and CAS- TWAS postdoctoral fellowship (No. 2014FFGB0004). Furthermore, the authors also acknowledged Shanghai Synchrotron Radiation Facility at Line BL15U (No. h15sr0021) used for X-ray fluorescence imaging.
Janus nanoparticles (JNPs) have multiple configurations for molecular imaging, targeting, and therapeutic effects on cancers; these properties have made these particles attractive for biomedical applications. Noneth...
This work was financially supported by the National Natural Science Foundation of China (NSFC) (Nos. 21473045 and 51401066), the Fundamental Research Funds from the Central University (PIRSOF HIT A201503), and the State Key Laboratory of Urban Water Resource and Environment, the Harbin Institute of Technology (No. 2018DX04).
Theranostic nanoagents that integrate the diagnoses and therapies within a single nanomaterial are compelling in their use for highly precise and efficient antitumor treatments. Herein, polyethylene glycol (PEG)-mod...
This study was supported by the National Natural Science Foundation of China (NSFC) (No. 81671829).
Molybdenum disulfide (MoS2), a typical transition-metal dichalcogenide, has attracted increasing attention in the field of nanomedicine because of its preeminent properties. In this study, magnetic resonance imaging...