云南高校图书馆联盟文献共享服务平台- MDR

MDR: 作品数：853被引量：3439H指数：17; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杨纯正杨佩满肖和平邢立强史立武更多>>; 相关机构：华中科技大学重庆医科大学大连医科大学中南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金深圳市科技计划项目山东省自然科学基金“九五”国家科技攻关计划更多>>

Structurally diverse sesquiterpenoids with anti-MDR cancer activity from Penicillium roqueforti: 《Chinese Journal of Natural Medicines》2025年第4期504-512,共9页Shuyuan Mo Nanjin Ding Zhihong Huang Jun Yao Weiguang Sun Jianping Wang Yonghui Zhang Zhengxi Hu; supported by the National Natural Science Foundation of China(Nos.82273811,32470417,and U22A20380);the National Program for Support of Top-notch Young Professionals(No.0106514050);the Hubei Provincial Natural Science Foundationof China(No.2024AFA028);the National Key R&D Program of China(No.2021YFA0910500);the Science and Technology Major Project of Hubei Province(Nos.2021ACA012 and 2024BCB021);the Chinese Medicine Research Foundation of the Health Commission of Hubei Province(No.ZY2025Z013)。; Five novel nor-eremophilane-type sesquiterpenoids,peniroqueforins E–H and J(1–4 and 7),two new eremophilane-type sesquiterpenoids,peniroqueforins I and K(5 and 8),and a new eudesmane-type sesquiterpenoid,peniroquefo...; 关键词：Penicillium roqueforti SESQUITERPENOIDS Nor-sesquiterpenoids Anti-MDR cancer activity

美国沙漠科技公司MDRX无托步枪: 《轻兵器》2025年第4期3-3,共1页; 2014年,沙漠科技公司描出无托版MDR(Mcro Dyramic Rifte)步枪,首引起市场关注。2020年。该公司在MDR基础上推出MDRX步枪,其名际中的"X"代表aXtreme(极度的),表明对MDR的大幅改进。相比于MDR步枪,MDRX步枪枪身材料改用更耐冲击的聚合物,...; 关键词：MDR 沙漠耐冲击步枪聚合物

Role of P-Gp in Treatment of Cancer: 《Journal of Cancer Therapy》2025年第1期1-17,共17页Venkata Sai Nithin Reddy Yendapalli Kelley Williams Terry Oroszi; P-glycoprotein (P-gp), a member of the ATP-binding cassette (ABC) family of transporters, plays a crucial role in the development of multi-drug resistance (MDR) in cancer treatment. P-gp actively pumps chemotherapeuti...; 关键词：P-Glycoprotein (P-Gp) Multi-Drug Resistance (MDR) Cancer Treatment ABC Transporters Chemotherapy Resistance P-Gp Inhibitors Drug Efflux Mechanisms Fourth-Generation Inhibitors

Tumor microenvironment-responsive drug self-delivery systems to treat cancer and overcome MDR: 《Rare Metals》2025年第1期1-33,共33页Ling-Mei Li Yi-Pin Xie Yu-Rong Qin Hai-Ping Chu Hui Xie De-Jin Zang Teng Liu; supported by the National Natural Science Foundation of China(No.21907059);Shandong Province Chinese Medicine Science and Technology Development Project(No.M-2022258);the Young Scientist Development Foundation of Shandong First Medical University(No.202201-002);the Academic Promotion Program of Shandong First Medical University(Nos.2019LJ003 and 2019QL011).; Tumor microenvironment-responsive drug self-delivery systems utilize tumor microenvironment-responsive chemical bonds to link anti-tumor drugs,exploiting the hydrophilic and hydrophobic properties of different drugs t...; 关键词：Drug self-delivery system Metal drug Tumor microenvironment response Drug carrier Tumor multidrug resistance

探讨MDR-AB耐药性及耐药基因检测在住院患者中的临床价值: 《中文科技期刊数据库（文摘版）医药卫生》2025年第1期043-046,共4页钟青茹梅江波; 探讨MDR-AB耐药性及耐药基因检测在住院患者中的临床价值。方法收集我院2021年8月-2023年9月住院治疗期间各科室分离出100株多重耐药鲍曼不动杆菌(MDR-AB)作为研究对象,所有患者均进行耐药基因和耐药性检测。分析MDR-AB的耐药性与耐药...; 关键词：住院患者多重耐药鲍曼不动杆菌耐药性耐药基因

复方蜥蜴散对胃癌顺铂耐药裸鼠肠道菌群的影响: 《中成药》2024年第11期3776-3783,共8页李铮程翻娥刘彩月白星师小茜朱西杰李卫强; 国家自然科学基金项目(82260916);宁夏医科大学科学研究资助项目(XZ2023012)。; 目的探讨复方蜥蜴散对胃癌顺铂耐药裸鼠肿瘤的抑制作用及对肠道菌群的影响。方法32只SPF级雄性BALB/c裸鼠随机分为空白组(8只)和造模组(24只),造模组于右侧腋窝皮下注射顺铂耐药的人胃癌MKN45/DDP细胞悬液,制备胃癌裸鼠顺铂耐药模型。...; 关键词：复方蜥蜴散胃癌顺铂耐药肠道菌群多药耐药(MDR)蛋白

Alpha-bisabolol逆转ABCB1介导的肿瘤多药耐药及机制: 《细胞与分子免疫学杂志》2024年第11期968-975,共8页侯鑫妤于涛刘保杰邵旭龙尚子临林瑞惠陆永正王国辉冯卫国; 国家自然科学基金(81802905);山东省自然科学基金(ZR2020MH263)。; 目的研究alpha-红没药醇(alpha-bisabolol)是否能有效逆转ATP结合盒转运体B1(ABCB1)介导的肿瘤多药耐药(MDR)并探讨其机制。方法应用网络药理学技术分析仙鹤草(Agrimonia Eupatoria)的活性成分,预测其靶基因,并进行基因本体论(GO)与京...; 关键词：alpha-红没药醇 ATP结合盒转运体B1(ABCB1) 多药耐药(MDR)

A novel FAK-degrading PROTAC molecule exhibited both anti-tumor activities and efficient MDR reversal effects: 《Acta Pharmacologica Sinica》2024年第10期2174-2185,共12页Ming-shi Xu Xiao-fan Gu Cong Li Li-xuan Pan Zi-xia Zhu Meng Fan Yun Zhao Jian-fang Chen Xuan Liu Xiong-wen Zhang; supported by National Natural Science Foundation of China(No.82373317,882374085 and 82303818);the Science and Technology Commission of Shanghai Municipality(20S11902200);the Natural Science Foundation of Shanghai(23ZR1460500);the China Postdoctoral Science Foundation(2023M731106);Xinjiang Uygur Autonomous Region’s Tianchi Talent-Professor Program.; FAK(focal adhesion kinase)is widely involved in cancer growth and drug resistance development.Thus,FAK inhibition has emerged as an effective strategy for tumor treatment both as a monotherapy or in combination with o...; 关键词：FAK inhibitors PROTAC antitumor activity MDR reversal P-GP

Antimicrobial Resistance of Aeromonas spp.and Vibrio spp.Isolated from Fresh Pangasius Fish in Cambodia: 《Journal of Environmental Science and Engineering(B)》2024年第5期199-209,共11页Duk Seyha Chrun Rithy Nguon Samnang Sudsai Trevanich Nora Navarro-Gonzalez Ségolène Calvez Chea Rortana Venn Vutey; supported by grants from HEIP(Higher Education Improvement Project)Project and Royal University of Agriculture.; The study was conducted to identify Aeromonas spp.and Vibrio spp.from fresh Pangasius fish(n=153)in Cambodia and test their antimicrobial susceptibility to antibiotics.The samples were collected from different wet mar...; 关键词：Aeromonas spp. Vibrio spp. prevalence MDR AMR and Cambodia’s Pangasius.

A comparative study on antimicrobial susceptibility of uroculturome of humans in health and urinary tract infections: 《Infectious Diseases Research》2024年第3期9-21,共13页Bhoj Raj Singh Himani Agri; supported by grants received from CAAST-ACLH(NAHEP/CAAST/2018-19)of ICAR-World Bank-funded National Agricultural Higher Education Project(NAHEP).; Background:The uroculturome indicates the profile of culturable microbes inhabiting the urinary tract,and it is often required to do a urine culture to find an effective antimicrobial to treat urinary tract infections...; 关键词：uro-microbiome UTI antibiotic susceptibility testing herbal antimicrobials ESBL carbapenem resistance MDR multiple herbal drug resistance

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